Degranulation of eosinophils mediated by intercellular adhesion molecule-1 and its ligands is involved in adhesion molecule expression on endothelial cells–selective induction of VCAM-1

Autor: Tomokazu Kakazu, Takahiro Yamamoto, Susumu Iwasa, Osamu Urayama, Yoshimi Kobayashi, Hiroyuki Kayaba, Kyoko Iida, Jun Yamamoto, Junichi Chihara, Dai Kurachi

Publikováno v: Journal of Allergy and Clinical Immunology. 103:S452-S456

Background: Adhesion molecules and eosinophils may play an important role in the pathogenesis of allergic inflammatory reactions. Objective: We attempted to clarify eosinophil activation, such as degranulation, by signaling through adhesion molecule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fec118a49bcb1e6e084b85e7cb8e4c6
https://doi.org/10.1016/s0091-6749(99)70161-2

Contents, Vol. 104, Supplement 1, 1994

Autor: Hiroko Nagai, Shimpei Furusawa, Takao Shida, R. Ichimi, Enno Christophers, Yuichi Nakamura, Nobana Hayashi, Ikkou Higashimoto, Minoru Okuda, Dagmar Födinger, Takahiro Yamamoto, Dai Kurachi, Akiyoshi Konno, Akikatsu Kataura, M. Sakurai, Naoko Yoshida, Mahboob Hossain, Akio Mori, Oliver Kilgus, Kenji Tadokoro, Dieter Maurer, Hirokazu Okudaira, Kenichi Ochiai, Kazuyoshi Watanabe, Minoru Miyasato, Daniel G. Tenen, Michiko Ishizaki, Mika Ueno, Setsuya Fukuda, Jean-Pierre Kinet, Koji lto, Naoki Saita, Shigeki Nagashima, Hisao Tomioka, Osamu Kaminuma, Kiyoshi Togawa, Yoji Iikura, Kano Taguchi, Naohisa Kitamura, Takeshi Mishima, Koji Shirotori, Takashi Yamada, Yasuhiro Samejima, Hideo Shishido, Itsuko Miura, Yuji Kikuchi, Matsunobu Suko, Masayuki Ando, Georg Stingl, Kiyoshi Takatsu, Tomokazu Kakazu, Armin Rieger, Yohnosuke Kobayashi, Shigenori Nakajima, Tohru Kimura, Takafumi Etoh, Jun Atsuta, Ryouji Ichimi, Shigeru Takafuji, Fumiko Juji, Shingo Tsuda, Keisuke Masuyama, Yoko Nishizaki, H. Kamiya, Steven J. Ackerman, Hidemi Nakagawa, Mitsuomi Hirashima, Binghe Wang, Hiroya Takashima, Nobuhisa Terada, Shoso Yamamoto, J. Atsuta, Nobuo Tsuruoka, Jens-M. Schröder, Susumu Tsurufuji, Takao Fujisawa, Koji Asakura, Morie Sekiguchi, Go Matsuzaki, Keiko Kato, T. Fujisawa, Yuji Yamaguchi, Clemens A. Dahinden, Takeru Ishikawa, Junichi Chihara, Satoshi Takaki, Hiroko Saito, Hideo Enokihara, Yoshio Okubo, Norihisa Ogata, Yoshikazu Kameyoshi, Makoto Yoshida

Publikováno v: International Archives of Allergy and Immunology. 104:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bee5dba9689426be2a4f2c15daac04cd
https://doi.org/10.1159/000236737

Elevated local production of neopterin from alveolar macrophages in patients with internal lung diseases

Autor: Takahiro Yamamoto, Toshiko Mouri, Dai Kurachi, Mitsuyo Saito, Shigenori Nakajima, Junichi Chihara

Publikováno v: General pharmacology. 27(3)

1. We measured the neopterin level in the supernatant of cultured alveolar macrophages from patients with interstitial lung diseases (ILD patients) as a marker for the activation of alveolar macrophage. 2. In ILD patients, the supernatant neopterin l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adddd995a0bb3205805fd483801f58f
https://pubmed.ncbi.nlm.nih.gov/8723531

Increased eosinophil oxidative metabolism by treatment with soluble intercellular adhesion molecule-1

Autor: Tomokazu Kakazu, Shigenori Nakajima, Ikkou Higashimoto, Takahiro Yamamoto, Dai Kurachi, Junichi Chihara

Publikováno v: International archives of allergy and immunology. 108

Adhesion molecules may play an important role not only in adherence of inflammatory cells (particularly eosinophils) to an inflamed focus but also in activation of these cells. It is therefore of interest to evaluate eosinophil activation via interce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798cc896b98a14ad1eeab017ef64bd07
https://pubmed.ncbi.nlm.nih.gov/7549522

Adhesion to fibronectin augments eosinophil radical oxygen products

Autor: Takahiro Yamamoto, Ikkou Higashimoto, Tomokazu Kakazu, Junichi Chihara, Shigenori Nakajima, Dai Kurachi

Publikováno v: International archives of allergy and immunology. 108

Fibronectin, an extracellular matrix component, is a ligand for very late activation antigen (VLA)-4, which is one of the beta 1-integrin family of molecules expressed by eosinophils. This study examined the effect of adherence to fibronectin on radi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0989a3ddff1c2f1af7fb16514aad47ba
https://pubmed.ncbi.nlm.nih.gov/7549523