Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dai Ihara"'
Autor:
Takahiro Sogo, Shu Nakao, Tasuku Tsukamoto, Tomoe Ueyama, Yukihiro Harada, Dai Ihara, Tomoaki Ishida, Masato Nakahara, Koji Hasegawa, Yuka Akagi, Yasuyuki S. Kida, Osamu Nakagawa, Teruyuki Nagamune, Masahiro Kawahara, Teruhisa Kawamura
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-17 (2023)
Abstract Background Canonical Wnt signaling is involved in a variety of biological processes including stem cell renewal and differentiation, embryonic development, and tissue regeneration. Previous studies reported the stage-specific roles of the Wn
Externí odkaz:
https://doaj.org/article/a50927d4e15c4b8793a2df472c93b698
Autor:
Tomoaki Ishida, Tomoe Ueyama, Dai Ihara, Yukihiro Harada, Sae Nakagawa, Kaho Saito, Shu Nakao, Teruhisa Kawamura
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1737 (2023)
Induced pluripotent stem cells (iPSCs) are promising cell sources for regenerative medicine and disease modeling. iPSCs are commonly established by introducing the defined reprogramming factors Oct4, Sox2, Klf4, and c-Myc. However, iPSC reprogramming
Externí odkaz:
https://doaj.org/article/e25b61c3b24b49168f836a9b46715b20
Publikováno v:
European Cardiology Review, Vol 15, Iss , Pp - (2020)
Induced pluripotent stem cells (iPSCs) are derived from reprogrammed somatic cells by the introduction of defined transcription factors. They are characterised by a capacity for self-renewal and pluripotency. Human (h)iPSCs are expected to be used ex
Externí odkaz:
https://doaj.org/article/a4356f951c42478085d04105768d19b4
Autor:
Kawamura, Tomoaki Ishida, Tomoe Ueyama, Dai Ihara, Yukihiro Harada, Sae Nakagawa, Kaho Saito, Shu Nakao, Teruhisa
Publikováno v:
Biomedicines; Volume 11; Issue 6; Pages: 1737
Induced pluripotent stem cells (iPSCs) are promising cell sources for regenerative medicine and disease modeling. iPSCs are commonly established by introducing the defined reprogramming factors Oct4, Sox2, Klf4, and c-Myc. However, iPSC reprogramming
Autor:
Yasuaki Ikuno, Koichiro Watanabe, Yumi Kakeya, Shinsuke Ikeno, Toshimasa Nakabo, Ayano Narumoto, Yukie Kande, Tomoki Hayashi, Kahori Minami, Kasumi Nobuhiro, Yo Mabuchi, Shiho Nakamura, Hideyuki Okano, Dai Ihara, Hayato Naka-Kaneda
Molecular mechanisms of aging specific to each stem cell (SC) are being elucidated. However, the common molecular basis for senescence in various SCs remains largely unexplored. Here, we have shown that the dysregulation of DNA damage response (DDR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f19f5848acbf5e87290fd297759bb21e
https://doi.org/10.21203/rs.3.rs-2204556/v3
https://doi.org/10.21203/rs.3.rs-2204556/v3
Autor:
Munkhsoyol Erkhembaatar, Iroha Yamamoto, Fuduki Inoguchi, Kosuke Taki, Satoru Yamagishi, Leanne Delaney, Nishibe Mariko, Takaya Abe, Hiroshi Kiyonari, Carina Hanashima, Hayato Naka‐kaneda, Dai Ihara, Yu Katsuyama
Publikováno v:
Development, growth & differentiation.
When the regulation of axonal and dendritic growth is altered, the neuronal network becomes disordered, which may contribute to the development of psychiatric disorders. Some genome analyses have suggested relationships between mutations in strawberr
Publikováno v:
Development, Growth & Differentiation. 63:82-92
A basic helix-loop-helix transcription factor Hey2 is expressed in the ventricular myocardium and endocardium of mouse embryos, and Hey2 null mice die perinatally showing ventricular septal defect, dysplastic tricuspid valve and hypoplastic right ven
Autor:
Atsushi Kubo, Dai Ihara, Osamu Nakagawa, Yuji Arai, Toshihiko Ogura, Yusuke Watanabe, Yoshie Isomoto, Daiki Seya, Teruhisa Kawamura, Atsushi Nakano
Publikováno v:
Developmental Biology. 461:124-131
Development of multi-chambered heart is associated with spatio-temporal regulation of gene expression. A basic helix-loop-helix transcription factor Hey2 is specifically expressed in the embryonic mouse ventricles and is indispensable for ventricular
Autor:
Mayo Shigeta, Dai Ihara, Atsushi Kubo, Yoshie Isomoto, Yoshihiko Saito, Takaya Abe, Teruhisa Kawamura, Shuhei Ishii, Atsushi Nakano, Osamu Nakagawa, Taiki Uemoto, Yusuke Watanabe, Yuji Arai, Daiki Seya, Toshihiko Ogura
Publikováno v:
The Journal of Biological Chemistry
Thoracic great vessels such as the aorta and subclavian arteries are formed through dynamic remodeling of embryonic pharyngeal arch arteries (PAAs). Previous work has shown that loss of a basic helix-loop-helix transcription factor Hey1 in mice cause