Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dahong, Long"'
Autor:
Ying Lyu, Zhongqiang Su, Guosheng Ye, Xiulan He, Yue Liu, Qiao Yin, Fanbing Xie, Liping Xu, Yuncai Chen, Dahong Long
Publikováno v:
Experimental Gerontology, Vol 179, Iss , Pp 112243- (2023)
The differentiation of human induced pluripotent stem cells (hiPSCs) into functional dopaminergic neural precursors is the basis of cell therapy for Parkinson's disease (PD). However, the use of small molecule inhibitors/activators in the differentia
Externí odkaz:
https://doaj.org/article/3234bff69bcc43ddbb1b4f75773f0f90
Autor:
Zhuo Gong, Jingyi Huang, Biao Xu, Zhenri Ou, Le Zhang, Xiaohong Lin, Xiujuan Ye, Xuejian Kong, Dahong Long, Xiangdong Sun, Xiaosong He, Liping Xu, Qingqing Li, Aiguo Xuan
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation, and impaired neurogenesis. Urolithin A (UA), a gut-microbial metaboli
Externí odkaz:
https://doaj.org/article/b0c99ea370e64368b59421d4f2a0b91e
Autor:
Xiaosong He, Yanqun Liu, Xiaohong Lin, Falei Yuan, Dahong Long, Zhijun Zhang, Yongting Wang, Aiguo Xuan, Guo-Yuan Yang
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)
Abstract Background Netrin-1 functions largely via combined receptors and downstream effectors. Evidence has shown that astrocytes express netrin-1 receptors, including DCC and UNC5H2. However, whether netrin-1 influences the function of astrocytes w
Externí odkaz:
https://doaj.org/article/ad5644e7f3564f1d92ea316ff196f7b0
Autor:
Xi Zhang, Xiaosong He, Qingqing Li, Xuejian Kong, Zhenri Ou, Le Zhang, Zhuo Gong, Dahong Long, Jianhua Li, Meng Zhang, Weidong Ji, Wenjuan Zhang, Liping Xu, Aiguo Xuan
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1256-1269 (2017)
Although valproic acid (VPA), has been shown to induce neuronal differentiation of neural stem cells (NSCs), the underlying mechanisms remain poorly understood. Here we investigated if and how mammalian target of rapamycin (mTOR) signaling is involve
Externí odkaz:
https://doaj.org/article/aae458a3787b424793023366f3903f07
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
The effects of prolonged physical training on memory performance and underlying presynaptic mechanisms were investigated in old C57BL/6 mice. Training via voluntary running wheels was initiated at 16 months of age and continued for 5 months (1 h per
Externí odkaz:
https://doaj.org/article/8973ed0530cf4dd68b9a491100069239
Autor:
Lian Liu, Lulu Chen, Yuncai Chen, Qingning Wang, Michael Chen, Yun He, Dahong Long, Benke Xu, Guosheng Ye
Publikováno v:
Aging and disease, vol 13, iss 4
Background: Memory loss is the key symptom of Alzheimer's disease (AD). As successful drug treatments have not yet been identified, non-pharmaceutical intervention, such as physical exercise has been recognized as an effective strategy to improve mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e580b85d1325229d85da76ee2a97e58d
https://escholarship.org/uc/item/9zv061rt
https://escholarship.org/uc/item/9zv061rt
Autor:
Michael Chen, Lulu Chen, Yun He, Yuncai Chen, Qingning Wang, Guosheng Ye, Lian Liu, Benke Xu, Dahong Long
Background: Memory loss is the key symptom of Alzheimer's disease (AD). As successful drug treatments have not yet been identified, non-pharmaceutical intervention, such as physical exercise has been recognized as an effective strategy to improve mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11b4bc6f2ff55c9a679cef6407066189
https://doi.org/10.21203/rs.3.rs-864660/v1
https://doi.org/10.21203/rs.3.rs-864660/v1
The Effects of Physical Running on Dendritic Spines and Amyloid-beta Pathology in 3xTg-AD Male Mice.
Autor:
Benke Xu, Yun He, Lian Liu, Guosheng Ye, Lulu Chen, Qingning Wang, Chen, Michael, Yuncai Chen, Dahong Long
Publikováno v:
Aging & Disease; Aug2022, Vol. 13 Issue 4, p1293-1310, 18p
Publikováno v:
Brain structurefunction. 226(2)
The effects of early-life adversity (ELA) on dendritic differentiation of striatal neurons were investigated in the dorsal striatum including the dorsomedial striatum and dorsolateral striatum (DMS and DLS, respectively). An animal model of ELA was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ecebea706a8a46437d2d907cde8b851
https://pubmed.ncbi.nlm.nih.gov/33386419
https://pubmed.ncbi.nlm.nih.gov/33386419
Autor:
Yan Chen, Nianping Zhang, Huicong Lu, Rongrong Jiang, Aiguo Xuan, Dahong Long, Nan Hu, Qing Zhu
Publikováno v:
Molecular Medicine Reports
Alzheimer's disease (AD) is the most prevalent age-related neurodegenerative disorder. It is featured by the progressive accumulation of β-amyloid (Aβ) plaques and neurofibrillary tangles. This can eventually lead to a decrease of cholinergic neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaccf67e353e4f12bcbcc7f1d86deae
https://doi.org/10.3892/mmr.2020.10918
https://doi.org/10.3892/mmr.2020.10918