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Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

Autor: Fulcher, J, Mihaylova, B, O'Connell, R, Emberson, J, Blackwell, L, Reith, C, Koren, M, Tonkin, A, Ridker, P, Barnes, E, Ford, I, Kean, S, Trompet, S, Macfarlane, P, Cannon, C, Pedersen, TR, Wilhelmsen, L, LaRosa, J, Packard, C, Robertson, M, Young, R, Tobert, J, Flather, M, Goto, S, Kastelein, J, Newman, C, Shear, C, Varigos, J, White, H, Armitage, J, Davies, K, Halls, H, Harper, C, Herrington, W, Holland, L, Kirby, A, Oconnell, R, Preiss, D, Spata, E, Wilson, K, Lonn, E, Wanner, C, Koenig, W, Gotto, A, Kjekshus, J, Yusuf, S, Collins, R, Simes, J, Baigent, C, Keech, A, De Lemos, J, Braunwald, E, Blazing, M, Murphy, S, Downs, JR, Clearfield, M, Holdaas, H, Gordon, D, Davis, B, Dahlof, B, Poulter, N, Sever, P, Knopp, RH, Fellstrom, B, Jardine, A, Schmieder, R, Zannad, F, Colhoun, HM, Betteridge, DJ, Durrington, PN, Hitman, GA, Fuller, J, Neil, A, Sacks, F, Moye, L, Pfeffer, M, Hawkins, CM, Wedel, H, Wikstrand, J, Krane, V, Tavazzi, L, Maggioni, A, Marchioli, R, Tognoni, G, Franzosi, MG, Bowman, L, Landray, MJ, Parish, S, Peto, R, Sleight, P, Ridker, PM, Macmahon, S, Marschner, I, Shaw, J, Serruys, PW, Nakamura, H, Knatterud, G, Furberg, C, Byington, R, Sattar, N, Jukema, JW

Publikováno v: Lancet (London, England)
J Fam Pract
2019, ' Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials ', The Lancet, vol. 393, no. 10170, pp. 407-415 . https://doi.org/10.1016/S0140-6736(18)31942-1

Background: Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203a87637a419ad172911cdd27325c83
http://hdl.handle.net/10044/1/67913

Protocol for prospective collaborative overviews of major randomized trials of blood-pressure-lowering treatments. World Health Organization-International Society of Hypertension Blood Pressure Lowering Treatment Trialists' Collaboration

Autor: Black, H, Boissel, J, Brenner, B, Brown, M, Bulpitt, C, Chalmers, J, Collins, R, Cutler, J, Dahlof, B, Davis, B, Fagard, R, Fletcher, A, Furberg, C, Hansson, L, Kuramoto, K, Lewis, E, MacMahon, S, Mancia, G, Pitt, B, Poulter, N, Remuzzi, G, Sleight, P, Turner, R, Sever, P, Whelton, P

OBJECTIVE: To conduct prospectively planned overviews (meta-analyses) of the ongoing randomized trials of blood-pressure-lowering drugs. These overviews should provide reliable data about the effects of newer classes of blood-pressure-lowering drugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::b5add3224d24d6d90166cdca125783d4
https://ora.ox.ac.uk/objects/uuid:6b261555-8186-4a9c-b3b0-b73dd42784d8

Mitral Annular Calcification and Incident Embolic Stroke in Treated Hypertensive Patients: The LIFE echo-substudy

Autor: DE MARCO, MARINA, DE SIMONE, GIOVANNI, MIGLIORE, TERESA, Gerdts E, Casalnuovo G, Wachtell K, Boman K, Dahlof B, Devereux RB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::11e5785b8064f88bf17c66217a8bf512
http://hdl.handle.net/11588/495806

effects of apsirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention regimen for Effectively Avoiding Second Strokes (Profess) trial: a double-bind, active and placebo controled study

Autor: YUSUF, S, DIENER HC, SACCO RL, COTTON D, OUNPUU S, LAWTON WA PALESCH Y. MARTIN RH ALBERS GW, BATH P, BORNSTEIN N, CHAN BP, CHEN ST, CUNHA L, DAHLOF B, DE KEYSER J, DONNAN GA, ESTOL C, GORELICK P, GU V, HERMANSSON K, HILBRICH L, KASTE M, LU C, MACHNIG T, PAIS P, ROBERTS R, SKVORTSOVA V, TEAL P, TONI D, VANDERMAELEN C, VOIGT T, WEBER M, YOON BW, COMI , GIANCARLO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::e98fda351f881b22f20a2fe8d0becad1