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pro vyhledávání: '"Dahlheim Charles E"'
Autor:
Venkatramana M. Rao, Dahlheim Charles E, Andrew M. Kroetsch, Vikram Sadineni, Atul Saluja, Vishal Nashine, Amol Mungikar
Publikováno v:
Pharmaceutical Research. 31:1575-1587
To enable aggregation rate prediction over a broad temperature range for complex multi-domain proteins at high concentrations. Thermal unfolding, non-isothermal kinetics and storage stability studies were conducted on a model multi-domain protein (MD
Publikováno v:
Journal of Pharmaceutical Sciences. 94:409-422
BMS-188184, an anthracene derivative, has been found to form at least two complexes with β-cyclodextrin. The association/dissociation kinetics of the two complexes were extremely slow, with one complex requiring approximately 24 h, and the other com