Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Dahish Ajarim"'
Autor:
Hisham Alquaydheb, Abrar Alharbi, Ahmed Badran, Bader Alshamsan, Ghada Algwaiz, Mahmoud A Elshenawy, Dahish Ajarim
Publikováno v:
Clinical Medicine Insights: Case Reports, Vol 16 (2023)
SARS-CoV-2 infection induces myocardiopathy in 19% of severe cases, with a mortality rate of up to 51%. The mainstay of treatment is supportive care, steroids, and tocilizumab (anti-IL-6). This is a case of a 43-year-old woman diagnosed with hormone-
Externí odkaz:
https://doaj.org/article/9c172cb5089842babda82ce2a6df4b01
Autor:
Abdul K. Siraj, Rong Bu, Sandeep Kumar Parvathareddy, Kaleem Iqbal, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Wael Haqawi, Mark Diaz, Ingrid G. Victoria, Ismail A. Al-Badawi, Asma Tulbah, Fouad Al-Dayel, Dahish Ajarim, Khawla S. Al-Kuraya
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract The PALB2 gene is a breast cancer (BC) and ovarian cancer (OC) predisposition gene involved in the homologous recombination repair pathway. However, the prevalence and clinicopathological association of PALB2 pathogenic/likely pathogenic (PV
Externí odkaz:
https://doaj.org/article/0c97e2f47b824050854ac2fed92effc0
Autor:
Ahmed Badran, Saad Salman Ali, Tarek Ziad Arabi, Abdullaah Khaleel Hinkston, Abdullah Shaik, Mahmoud A Elshenawy, Dahish Ajarim
Publikováno v:
Clinical Medicine Insights: Case Reports, Vol 16 (2023)
Human epidermal growth factor receptor-positive breast cancer is an aggressive cancer which represents approximately a quarter of all breast cancers worldwide. Recent advances have led to the development of targeted therapies, such as trastuzumab (H)
Externí odkaz:
https://doaj.org/article/20370b27a9bf4f7085e2b7453d651670
Autor:
Abdul Khalid Siraj, Tariq Masoodi, Rong Bu, Sandeep Kumar Parvathareddy, Kaleem Iqbal, Saud Azam, Maha Al-Rasheed, Dahish Ajarim, Asma Tulbah, Fouad Al-Dayel, Khawla Sami Al-Kuraya
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 19, Iss 1, Pp 1-9 (2021)
Abstract Background The data on prevalence and clinical relevance of TP53 germline mutations in early onset Middle-Eastern breast cancer (BC) is limited. Methods We determined TP53 germline mutations in a cohort of 464 early onset BC patients from Sa
Externí odkaz:
https://doaj.org/article/69aadafd781648d29b443baea330bfaf
Autor:
Hazem Ghebeh, Adher Al-Sayed, Riham Eiada, Leilani Cabangon, Dahish Ajarim, Kausar Suleman, Asma Tulbah, Taher Al-Tweigeri
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Therapeutic anti-PD-L1 antibodies are safe as a monotherapy, albeit with minimal efficacy in triple-negative breast cancer (TNBC). This trial aimed to test the safety and efficacy of Durvalumab and Paclitaxel in metastatic TNBC. In this open
Externí odkaz:
https://doaj.org/article/4082da344ce44ce6b8b8a7859e11152b
Autor:
Azhar R. Hussain, Abdul Khalid Siraj, Maqbool Ahmed, Rong Bu, Poyil Pratheeshkumar, Alanood M. Alrashed, Zeeshan Qadri, Dahish Ajarim, Fouad Al-Dayel, Shaham Beg, Khawla S. Al-Kuraya
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Breast cancer is the most common cancer in females and is ranked second in cancer-related deaths all over the world in women. Despite improvement in diagnosis, the survival rate of this disease has still not improved. X-linked Inh
Externí odkaz:
https://doaj.org/article/a0f64280cf4344bcbfc09b5c2ba7c060
Autor:
Sandeep Kumar Parvathareddy, Abdul K. Siraj, Saeeda O. Ahmed, Laila Omar Ghazwani, Saud M. Aldughaither, Fouad Al-Dayel, Asma Tulbah, Dahish Ajarim, Khawla S. Al-Kuraya
Publikováno v:
Cells, Vol 10, Iss 2, p 229 (2021)
Programmed cell-death ligand 1 (PD-L1) has been shown to induce potent T-cell mediated anti-tumoral immunity. The significance of PD-L1 expression in the prognosis of breast cancer (BC) remains controversial and its prevalence and prognostic value in
Externí odkaz:
https://doaj.org/article/216ec82ead264630a5da9d690488c04e
Autor:
Hazem Ghebeh, Shamayel Mohammed, Abeer Al-Omair, Amal Qattant, Cynthia Lehe, Ghofran Al-Qudaihi, Naser Elkum, Mohamed Alshabanah, Suad Bin Amer, Asma Tulbah, Dahish Ajarim, Taher Al-Tweigeri, Said Dermime
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 3, Pp 190-198 (2006)
B7-H1 molecule increases the apoptosis of tumorreactive T lymphocytes and reduces their immunogenicity. Breast cancer is the second most common cause of mortality after lung cancer. Direct evidence linking B7-H1 with cancer has been shown in several
Externí odkaz:
https://doaj.org/article/6426c66bcdcc45a8b972ad2e1c875400
Autor:
Dilek Colak, Asmaa Nofal, Albandary Albakheet, Maimoona Nirmal, Hatim Jeprel, Abdelmoneim Eldali, Taher Al-Tweigeri, Asma Tulbah, Dahish Ajarim, Osama Al Malik, Mehmet S Inan, Namik Kaya, Ben H Park, Suad M Bin Amer
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63204 (2013)
Breast cancer in young women is more aggressive with a poorer prognosis and overall survival compared to older women diagnosed with the disease. Despite recent research, the underlying biology and molecular alterations that drive the aggressive natur
Externí odkaz:
https://doaj.org/article/9e7734d777dc40e89c18983a62fde4ef
Autor:
Monther Al-Alwan, Safiah Olabi, Hazem Ghebeh, Eman Barhoush, Asma Tulbah, Taher Al-Tweigeri, Dahish Ajarim, Chaker Adra
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27339 (2011)
The actin-bundling protein, fascin, is a member of the cytoskeletal protein family that has restricted expression in specialized normal cells. However, many studies have reported the induction of this protein in various transformed cells including br
Externí odkaz:
https://doaj.org/article/db6063dfabfd4160b6734f1e900dc24e