Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dagmara Mohuczy"'
Publikováno v:
Seminars in Interventional Radiology. 25:092-103
The atrophy-hypertrophy complex (AHC) refers to the controlled restoration of liver parenchyma following hepatocyte loss. Different types of injury (e.g., toxins, ischemia/reperfusion, biliary obstruction, and resection) elicit the same hypertrophic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce69e38fbd33b43ce94469566858a4e
https://doi.org/10.1055/s-2008-1076679
https://doi.org/10.1055/s-2008-1076679
Autor:
Kerri A. O’Malley, Takashi Nitta, Kevin E. Behrns, Lyle L. Moldawer, Dagmara Mohuczy, William A. Dunn, Jae-Sung Kim
Publikováno v:
Hepatology. 47:1725-1736
Hepatocyte ischemia during liver transplantation, resection, and shock causes anoxia, depletion of glycolytic substrates, loss of adenosine triphosphate (ATP), and acidosis.1 When blood flow returns to hepatocytes, the normal oxygen concentration and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6717d5c0bdd5ef479a7a668c5fec478f
https://doi.org/10.1002/hep.22187
https://doi.org/10.1002/hep.22187
Publikováno v:
Cancer Chemotherapy and Pharmacology. 59:127-136
Purpose: Aldehyde dehydrogenases class-1A1 (ALDH1A1) and class-3A1 (ALDH3A1) have been associated with resistance to cyclophosphamide (CP) and its derivatives. We have previously reported the downregulation of these enzymes by all-trans retinoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d72e7c06d395739570908003823401
https://doi.org/10.1007/s00280-006-0233-6
https://doi.org/10.1007/s00280-006-0233-6
Autor:
Santosh Gowda, James R. Zucali, Govind R. Vartikar, Dagmara Mohuczy, Jan S. Moreb, Amir A Gabr
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 312:339-345
Multiple prior studies have identified aldehyde dehydrogenases (ALDH) that are capable of oxidizing retinal to retinoic acid. In this study, we test the hypothesis that the accumulation of intracellular retinoic acid may lead to the suppression of AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af79ad6f180c0529b6bbb3b6f45738f7
https://doi.org/10.1124/jpet.104.072496
https://doi.org/10.1124/jpet.104.072496
Autor:
M. Ian Phillips, Dagmara Mohuczy
Publikováno v:
Molecular and Cellular Biochemistry. 212:145-153
Overactive renin-angiotensin system has been indicated in numerous pathological situations. Current treatment is based on pharmaceutical compounds, which work on the proteins level. Undisputedly helpful, it is not, however, flawless. Some of the draw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac2443172bcb23464b1c0061dc3263f
https://doi.org/10.1023/a:1007192624989
https://doi.org/10.1023/a:1007192624989
Autor:
Paulette Mehta, Leping Shen, Dagmara Mohuczy, Hongbin Meng, Jason Mehta, M. I. Phillips, B. C. Yang
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 18:1433-1439
Abstract —Angiotensin II (Ang II) promotes vascular smooth muscle growth and may be involved in the initiation and progression of atherosclerosis. To examine whether Ang II receptor expression in vascular tissues is altered in atherosclerosis, male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c120ac0eaa311197510f32c57bc25e
https://doi.org/10.1161/01.atv.18.9.1433
https://doi.org/10.1161/01.atv.18.9.1433
Publikováno v:
Hepatology (Baltimore, Md.). 48(3)
Hepatocytes that reside in a chronically-injured liver have altered growth responses compared to hepatocytes in normal liver. Transforming growth factor beta (TGFβ) is upregulated in the cirrhotic liver, and cirrhotic hepatocytes, unlike normal hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6577ae92c3594f6a4efac2b316524c2
https://pubmed.ncbi.nlm.nih.gov/18712785
https://pubmed.ncbi.nlm.nih.gov/18712785
Autor:
Kevin E. Behrns, Suzanne Lyman, Takashi Nitta, Dagmara Mohuczy, John J. Lemasters, Jae-Sung Kim, Jay S. Raval
Publikováno v:
Free radical biologymedicine. 41(11)
Hepatocytes from cirrhotic murine livers exhibit increased basal ROS activity and resistance to TGFbeta-induced apoptosis, yet when ROS levels are decreased by antioxidant pretreatment, these cells recover susceptibility to apoptotic stimuli. To furt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8890eb33d147852c24706957125b75
https://pubmed.ncbi.nlm.nih.gov/17145552
https://pubmed.ncbi.nlm.nih.gov/17145552
Autor:
Katherine L. Gaston, Jennifer S. Tromberg, Julie A. Johnson, Hossein Yarandi, Mark J. Chirico, Dagmara Mohuczy, Cassandra D. Waddell, Larry M. Lopez, Taimour Y. Langaee, Christina L. Aquilante
Publikováno v:
Clinical pharmacology and therapeutics. 79(4)
Introduction The primary objective of this study was to determine whether variability in warfarin dose requirements is determined by common polymorphisms in genes whose products are involved in the pharmacodynamics and pharmacokinetics of warfarin, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ebb7c2474b43b442b14ca0a4e9701a
https://pubmed.ncbi.nlm.nih.gov/16580898
https://pubmed.ncbi.nlm.nih.gov/16580898
Autor:
Dagmara Mohuczy, M. Ian Phillips
Antisense inhibition has been developed, particularly in cell-culture applications, to the point where it is being tested in clinical trials for HIV and cancer (1,2). The pros and cons of its use have been reviewed elsewhere (3). Before 1992, however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97b9b2c2e35905c2c60068763cffebad
https://doi.org/10.1385/1-59259-087-x:83
https://doi.org/10.1385/1-59259-087-x:83
