Výsledky vyhledávání - "Dagmara I Kisiela"

Akademický článek

Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core.

Autor: Dagmara I Kisiela, Pearl Magala, Gianluca Interlandi, Laura A Carlucci, Angelo Ramos, Veronika Tchesnokova, Benjamin Basanta, Vladimir Yarov-Yarovoy, Hovhannes Avagyan, Anahit Hovhannisyan, Wendy E Thomas, Ronald E Stenkamp, Rachel E Klevit, Evgeni V Sokurenko

Publikováno v: PLoS Pathogens, Vol 17, Iss 4, p e1009440 (2021)

Critical molecular events that control conformational transitions in most allosteric proteins are ill-defined. The mannose-specific FimH protein of Escherichia coli is a prototypic bacterial adhesin that switches from an 'inactive' low-affinity state

Externí odkaz: https://doaj.org/article/92724f2113474eaeae020cdd9e9e6a36

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Akademický článek

Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli.

Autor: Dagmara I Kisiela, Hovhannes Avagyan, Della Friend, Aachal Jalan, Shivani Gupta, Gianluca Interlandi, Yan Liu, Veronika Tchesnokova, Victoria B Rodriguez, John P Sumida, Roland K Strong, Xue-Ru Wu, Wendy E Thomas, Evgeni V Sokurenko

Publikováno v: PLoS Pathogens, Vol 11, Iss 5, p e1004857 (2015)

Attachment proteins from the surface of eukaryotic cells, bacteria and viruses are critical receptors in cell adhesion or signaling and are primary targets for the development of vaccines and therapeutic antibodies. It is proposed that the ligand-bin

Externí odkaz: https://doaj.org/article/62ac6508696e4e46905fadab9acd7553

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Akademický článek

Evolution of Salmonella enterica virulence via point mutations in the fimbrial adhesin.

Autor: Dagmara I Kisiela, Sujay Chattopadhyay, Stephen J Libby, Joyce E Karlinsey, Ferric C Fang, Veronika Tchesnokova, Jeremy J Kramer, Viktoriya Beskhlebnaya, Mansour Samadpour, Krzysztof Grzymajlo, Maciej Ugorski, Emily W Lankau, Roderick I Mackie, Steven Clegg, Evgeni V Sokurenko

Publikováno v: PLoS Pathogens, Vol 8, Iss 6, p e1002733 (2012)

Whereas the majority of pathogenic Salmonella serovars are capable of infecting many different animal species, typically producing a self-limited gastroenteritis, serovars with narrow host-specificity exhibit increased virulence and their infections

Externí odkaz: https://doaj.org/article/5718067cd6364802a7764599f2dc22bd

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Pandemic fluoroquinolone resistant Escherichia coli clone ST1193 emerged via simultaneous homologous recombinations in 11 gene loci

Autor: Veronika Tchesnokova, Lydia Larson, Matthew C. Radey, Evgeni V. Sokurenko, Dagmara I. Kisiela, Sujay Chattopadhyay, Jamie Lee Weaver

Publikováno v: Proceedings of the National Academy of Sciences. 116:14740-14748

Global growth in antibiotic resistance is a major social problem. A high level of resistance to fluoroquinolones requires the concurrent presence of at least 3 mutations in the target proteins—2 in DNA gyrase (GyrA) and 1 in topoisomerase IV (ParC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c9ada723f5fdcd9073b8a10c6dbb85
https://doi.org/10.1073/pnas.1903002116

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Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core

Autor: Hovhannes Avagyan, Rachel E. Klevit, Laura A. Carlucci, Evgeni V. Sokurenko, Benjamin Basanta, Dagmara I. Kisiela, Angelo Ramos, Wendy E. Thomas, Ronald E. Stenkamp, Pearl Magala, Veronika Tchesnokova, Vladimir Yarov-Yarovoy, Anahit Hovhannisyan, Gianluca Interlandi

Publikováno v: PLoS pathogens, vol 17, iss 4
PLoS Pathogens, Vol 17, Iss 4, p e1009440 (2021)
PLoS Pathogens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76213e01c3c0afb912f1ba322843b6b0
https://escholarship.org/uc/item/0j29f4b5

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Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-Cov-2 variants

Autor: Kai Deng, Elena Rechkina, Evgeni V. Sokurenko, Veronika Tchesnokova, Mansour Samadpour, Lydia Larson, James D. Ralston, Curtis Fowler, Kirthi K. Kutumbaka, Dagmara I. Kisiela, Hao Geng, Victoria Bowers, Yulia Sledneva, Dina N. Greene, Debarati Choudhury, Iryna Maslova, Hemantha Kulasekara

Publikováno v: Journal of Clinical Microbiology
bioRxiv

The recent rise in mutational variants of SARS-CoV-2, especially with changes in the Spike protein, is of significant concern due to the potential ability for these mutations to increase viral infectivity, virulence and/or ability to escape protectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c60ee10e35e5a0b5d5fa735fe64005
https://doi.org/10.1101/2021.02.22.432189

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FimH as a scaffold for regulated molecular recognition

Autor: Shivani Gupta Ludwig, Casey L. Kiyohara, Laura A. Carlucci, Wendy E. Thomas, Dagmara I. Kisiela, Evgeni V. Sokurenko

Publikováno v: Journal of Biological Engineering
Journal of Biological Engineering, Vol 15, Iss 1, Pp 1-12 (2021)

BackgroundRecognition proteins are critical in many biotechnology applications and would be even more useful if their binding could be regulated. The current gold standard for recognition molecules, antibodies, lacks convenient regulation. Alternativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea542f465311cdc7b2336b3f0967da9
http://europepmc.org/articles/PMC7805223

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Escherichia coli Clonobiome: Assessing the Strain Diversity in Feces and Urine by Deep Amplicon Sequencing

Autor: Sofiya Shevchenko, Dagmara I. Kisiela, Veronika Tchesnokova, Evgeni V. Sokurenko, Matthew C. Radey

Publikováno v: Appl Environ Microbiol

While microbiome studies have focused on diversity on the species or higher level, bacterial species in microbiomes are represented by different, often multiple strains. These strains could be clonally and phenotypically very different, making assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cfb1c1cf341091108cbc7e8a0070ea
https://pubmed.ncbi.nlm.nih.gov/31540992

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Inactivation of Transcriptional Regulators during Within-Household Evolution of Escherichia coli

Autor: Stephen B. Porter, Lance B. Price, Sofiya Shevchenko, Evgeni V. Sokurenko, Kseniya Polukhina, Diana Chan, Veronika Tchesnokova, Maliha Aziz, Matthew C. Radey, Dagmara I. Kisiela, Timothy J. Johnson, Sandip Paul, James R. Johnson

Publikováno v: Journal of Bacteriology. 199

We analyzed the within-household evolution of two household-associated Escherichia coli strains from pandemic clonal group ST131- H 30, using isolates recovered from five individuals within two families, each of which had a distinct strain. Family 1'

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d20cf25a64edec0472820e58d3d6ed
https://doi.org/10.1128/jb.00036-17

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Structural and Population Characterization of MrkD, the Adhesive Subunit of Type 3 Fimbriae

Autor: Carsten Struve, Steven Clegg, Dagmara I. Kisiela, Evgeni V. Sokurenko, Karen A. Krogfelt, Steen Gustav Stahlhut, Kristian Hvidtfeldt, Sujay Chattopadhyay

Publikováno v: Journal of Bacteriology. 195:5602-5613

Type 3 fimbriae are adhesive organelles found in enterobacterial pathogens. The fimbriae promote biofilm formation on biotic and abiotic surfaces; however, the exact identity of the receptor for the type 3 fimbriae adhesin, MrkD, remains elusive. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9439a0438cf89f9c007a0ad77ffde566
https://doi.org/10.1128/jb.00753-13

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