Bovine milk somatic cell transcriptomic response to Staphylococcus aureus is dependent on strain genotype

Autor: Dagmara A. Niedziela, Paul Cormican, Gilles Foucras, Finola C. Leonard, Orla M. Keane

Publikováno v: BMC Genomics, Vol 22, Iss 1, Pp 1-20 (2021)

Abstract Background Mastitis is an economically important disease of dairy cows with Staphylococcus aureus a major cause worldwide. Challenge of Holstein-Friesian cows demonstrated that S. aureus strain MOK124, which belongs to Clonal Complex (CC)151

Externí odkaz: https://doaj.org/article/f85878dc818e4bd491d6656e62eba73b

Multiclonal human origin and global expansion of an endemic bacterial pathogen of livestock

Autor: Gonzalo Yebra, Joshua D. Harling-Lee, Samantha Lycett, Frank M. Aarestrup, Gunhild Larsen, Lina M. Cavaco, Keun Seok Seo, Sam Abraham, Jacqueline M. Norris, Tracy Schmidt, Marthie M. Ehlers, Daniel O. Sordelli, Fernanda R. Buzzola, Wondwossen A. Gebreyes, Juliano L. Gonçalves, Marcos V. dos Santos, Zunita Zakaria, Vera L. M. Rall, Orla M. Keane, Dagmara A. Niedziela, Gavin K. Paterson, Mark A. Holmes, Tom C. Freeman, J. Ross Fitzgerald

Publikováno v: Yebra, G, Harling-Lee, J D, Lycett, S, Aarestrup, F M, Larsen, G, Cavaco, L M, Seo, K S, Abraham, S, Norris, J M, Schmidt, T, Ehlers, M M, Sordelli, D O, Buzzola, F R, Gebreyes, W A, Gonçalves, J L, dos Santos, M V, Zakaria, Z, Rall, V L M, Keane, O M, Niedziela, D A, Paterson, G K, Holmes, M A, Freeman, T C & Fitzgerald, J R 2022, ' Multiclonal human origin and global expansion of an endemic bacterial pathogen of livestock ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 50, e2211217119 . https://doi.org/10.1073/pnas.2211217119

Peer reviewed: True
Most new pathogens of humans and animals arise via switching events from distinct host species. However, our understanding of the evolutionary and ecological drivers of successful host adaptation, expansion, and dissemination

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe3e98ff202f3f665ce8225b4cf664e
https://pubmed.ncbi.nlm.nih.gov/36469788

A study of the correlation between phenotypic antimicrobial susceptibility testing methods and the associated genotypes determined by whole genome sequencing for a collection of Escherichia coli of bovine origin

Autor: Emmanuel Cuinet, Séamus Fanning, Frédérique Woehrlé, Scott V. Nguyen, Farid El Garach, Christine Miossec, Dagmara A. Niedziela, Thomas J Maunsell

Antimicrobial resistance (AMR) has increased at an alarming pace in the recent years. Molecular-based methods such as whole genome sequencing (WGS) offer a potential alternative to the conventional labour-intensive methods traditionally used to chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a02df49b1e733c7ee5c6d15eaf6f843
https://doi.org/10.1101/2021.07.16.452668

Clinical presentation and immune characteristics in first-lactation Holstein-Friesian cows following intramammary infection with genotypically distinct Staphylococcus aureus strains

Autor: Jim Grant, Finola C. Leonard, Dagmara A. Niedziela, Orla M. Keane, Mark P. Murphy

Publikováno v: Journal of dairy science. 103(9)

Staphylococcus aureus is an important cause of bovine mastitis, and intramammary infections caused by this pathogen are often characterized as mild, chronic, or persistent. The strains of Staph. aureus associated with mastitis belong to several disti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710d444ff9d3aee7fdd8fe5a86b5a240
https://pubmed.ncbi.nlm.nih.gov/32622604