Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Dagmar Zeuschner"'
Publikováno v:
Advanced Science, Vol 11, Iss 16, Pp n/a-n/a (2024)
Abstract Weibel Palade bodies (WPB) are lysosome‐related secretory organelles of endothelial cells. Commonly known for their main cargo, the platelet and leukocyte receptors von‐Willebrand factor (VWF) and P‐selectin, WPB play a crucial role in
Externí odkaz:
https://doaj.org/article/925af5699cd448a886c87e868c414711
Autor:
Lampros Mavrommatis, Hyun-Woo Jeong, Urs Kindler, Gemma Gomez-Giro, Marie-Cecile Kienitz, Martin Stehling, Olympia E Psathaki, Dagmar Zeuschner, M Gabriele Bixel, Dong Han, Gabriela Morosan-Puopolo, Daniela Gerovska, Ji Hun Yang, Jeong Beom Kim, Marcos J Arauzo-Bravo, Jens C Schwamborn, Stephan A Hahn, Ralf H Adams, Hans R Schöler, Matthias Vorgerd, Beate Brand-Saberi, Holm Zaehres
Publikováno v:
eLife, Vol 12 (2023)
In vitro culture systems that structurally model human myogenesis and promote PAX7+ myogenic progenitor maturation have not been established. Here we report that human skeletal muscle organoids can be differentiated from induced pluripotent stem cell
Externí odkaz:
https://doaj.org/article/2882c4b7b3864986853c1bc24996070e
Autor:
Simone Rey, Henrike Ohm, Frederieke Moschref, Dagmar Zeuschner, Marit Praetz, Christian Klämbt
Publikováno v:
eLife, Vol 12 (2023)
Neuronal information conductance often involves the transmission of action potentials. The spreading of action potentials along the axonal process of a neuron is based on three physical parameters: the axial resistance of the axon, the axonal insulat
Externí odkaz:
https://doaj.org/article/1fba3ed44618406395436f4c01bc53ef
Autor:
Nikita Raj, Lilo Greune, Martin Kahms, Karina Mildner, Rico Franzkoch, Olympia Ekaterini Psathaki, Thomas Zobel, Dagmar Zeuschner, Jürgen Klingauf, Volker Gerke
Publikováno v:
Advanced Science, Vol 10, Iss 13, Pp n/a-n/a (2023)
Abstract The plasma membrane of a cell is subject to stresses causing ruptures that must be repaired immediately to preserve membrane integrity and ensure cell survival. Yet, the spatio‐temporal membrane dynamics at the wound site and the source of
Externí odkaz:
https://doaj.org/article/aa493a636a924d8e9c05972c84759dcb
Autor:
Hatice O. Ozguldez, Niraimathi Govindasamy, Rui Fan, Hongyan Long, Karina Mildner, Dagmar Zeuschner, Britta Trappmann, Adrian Ranga, Ivan Bedzhov
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112313- (2023)
Summary: The extra-embryonic tissues that form the placenta originate from a small population of trophectoderm cells with stem cell properties, positioned at the embryonic pole of the mouse blastocyst. During the implantation stages, the polar trophe
Externí odkaz:
https://doaj.org/article/9a1b8f52eb104a7696873ecda0c63af1
Autor:
Binyamin Duethorn, Fabian Groll, Bettina Rieger, Hannes C. A. Drexler, Heike Brinkmann, Ludmila Kremer, Martin Stehling, Marie-Theres Borowski, Karina Mildner, Dagmar Zeuschner, Magdalena Zernicka-Goetz, Marc P. Stemmler, Karin B. Busch, Juan M. Vaquerizas, Ivan Bedzhov
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
How pluripotency transcription factors regulate the cellular architecture and energetics has remained largely unknown. Here the authors identify Lima1 as a key effector that mediates the pluripotency control of membrane dynamics and cellular metaboli
Externí odkaz:
https://doaj.org/article/ec59b98c93f041c9b516251c4f4d904c
Autor:
Kishor K. Sivaraj, Paul-Georg Majev, Hyun-Woo Jeong, Backialakshmi Dharmalingam, Dagmar Zeuschner, Silke Schröder, M. Gabriele Bixel, Melanie Timmen, Richard Stange, Ralf H. Adams
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Developmental and regenerative bone formation require the removal of chondrocytes and matrix. Here the authors show that these processes involve mesenchymal stromal cell-derived septoclasts, which disappear after the completion of development but re-
Externí odkaz:
https://doaj.org/article/87e8bb520b23402b80417daafdf1bb0e
Autor:
Jifeng Liu, Hongyan Long, Dagmar Zeuschner, Andreas F. B. Räder, William J. Polacheck, Horst Kessler, Lydia Sorokin, Britta Trappmann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Current tissue engineering strategies lack materials that promote angiogenesis. Here the authors develop a microfluidic in vitro model in which chemokine-guided endothelial cell sprouting into a tunable hydrogel is followed by the formation of perfus
Externí odkaz:
https://doaj.org/article/44b2977179d84acea256312132cf8fe7
Autor:
Rui Fan, Yung Su Kim, Jie Wu, Rui Chen, Dagmar Zeuschner, Karina Mildner, Kenjiro Adachi, Guangming Wu, Styliani Galatidou, Jianhua Li, Hans R. Schöler, Sebastian A. Leidel, Ivan Bedzhov
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Embryonic diapause is a state of dormancy with poorly understood mechanisms of embryo intrinsic regulation. Here, the authors show that murine diapause is a dynamic process, where tissue-scale reorganization of the pluripotent lineage is controlled i
Externí odkaz:
https://doaj.org/article/8ca51a4f837f4e888adc4dfe1fda8fa3
Autor:
Gemma Gomez-Giro, Jonathan Arias-Fuenzalida, Javier Jarazo, Dagmar Zeuschner, Muhammad Ali, Nina Possemis, Silvia Bolognin, Rashi Halder, Christian Jäger, Willemijn F. E. Kuper, Peter M. van Hasselt, Holm Zaehres, Antonio del Sol, Herman van der Putten, Hans R. Schöler, Jens C. Schwamborn
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-19 (2019)
Abstract The juvenile form of neuronal ceroid Lipofuscinosis (JNCL) is the most common form within this group of rare lysosomal storage disorders, causing pediatric neurodegeneration. The genetic disorder, which is caused by recessive mutations affec
Externí odkaz:
https://doaj.org/article/e28ca03024ec42bf892e968c69946796