Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dagmar Schumacher"'
Autor:
Susanne Gaul, Khurrum Shahzad, Rebekka Medert, Ihsan Gadi, Christina Mäder, Dagmar Schumacher, Angela Wirth, Saira Ambreen, Sameen Fatima, Jes-Niels Boeckel, Hamzah Khawaja, Jan Haas, Maik Brune, Peter P. Nawroth, Berend Isermann, Ulrich Laufs, Marc Freichel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveAtherosclerosis, the main pathology underlying cardiovascular diseases is accelerated in diabetic patients. Genetic mouse models require breeding efforts which are time-consuming and costly. Our aim was to establish a new nongenetic model of
Externí odkaz:
https://doaj.org/article/56c5ef21b0ed4df3b798f8eedcf9f944
Autor:
Dagmar Schumacher, Jakob Morgenstern, Yoko Oguchi, Nadine Volk, Stefan Kopf, Jan Benedikt Groener, Peter Paul Nawroth, Thomas Fleming, Marc Freichel
Publikováno v:
Molecular Metabolism, Vol 18, Iss , Pp 143-152 (2018)
Objectives: The deficit of Glyoxalase I (Glo1) and the subsequent increase in methylglyoxal (MG) has been reported to be one the five mechanisms by which hyperglycemia causes diabetic late complications. Aldo-keto reductases (AKR) have been shown to
Externí odkaz:
https://doaj.org/article/ab909cb76d024a0a9c7acda54454efcc
Autor:
Julia Hermann, Melanie Bender, Dagmar Schumacher, Marcel S. Woo, Artem Shaposhnykov, Sina C. Rosenkranz, Vladimir Kuryshev, Chris Meier, Andreas H. Guse, Manuel A. Friese, Marc Freichel, Volodymyr Tsvilovskyy
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger that evokes calcium release from intracellular organelles by the engagement of calcium release channels, including members of the Transient Receptor Potential (TRP) family, s
Externí odkaz:
https://doaj.org/article/f05989ec816e4f3484804e0ab602b2d8
Autor:
Robin Sachdeva, Andrea Schlotterer, Dagmar Schumacher, Christin Matka, Ilka Mathar, Nadine Dietrich, Rebekka Medert, Ulrich Kriebs, Jihong Lin, Peter Nawroth, Lutz Birnbaumer, Thomas Fleming, Hans-Peter Hammes, Marc Freichel
Publikováno v:
Molecular Metabolism, Vol 9, Iss , Pp 156-167 (2018)
Objective: Diabetic retinopathy (DR) is induced by an accumulation of reactive metabolites such as ROS, RNS, and RCS species, which were reported to modulate the activity of cation channels of the TRPC family. In this study, we use Trpc1/4/5/6−/−
Externí odkaz:
https://doaj.org/article/6e5ee3b073824294af4b0ed7ec6a90ef
Autor:
Veit Flockerzi, Martin Busch, Patrick Most, Rebekka Medert, Dirk Grimm, Staffan Hildebrand, Dagmar Schumacher, Oliver J. Müller, Andreas Jungmann, Marc Freichel
Publikováno v:
Pflugers Archiv
The cation channel transient receptor potential melastatin 4 (TRPM4) is a calcium-activated non-selective cation channel and acts in cardiomyocytes as a negative modulator of the L-type Ca2+ influx. Global deletion of TRPM4 in the mouse led to increa
Autor:
Ayse Sanlialp, Shirin Doroudgar, Leon Kiper, Frank Zimmermann, Agnieszka A. Gorska, Sascha Dlugosz, Hugo A. Katus, Mirko Völkers, Jana Burghaus, Eshita Varma, Dagmar Schumacher, Juan E. Camacho Londoño, Marc Freichel, Eva Riechert, Vivien Kmietczyk, Angela Wirth, Thanh Cao Ho, Christoph Hofmann
Publikováno v:
Journal of Molecular and Cellular Cardiology. 141:30-42
Pathological cardiac hypertrophy is an independent risk for heart failure (HF) and sudden death. Deciphering signaling pathways regulating intracellular Ca2+ homeostasis that control adaptive and pathological cardiac growth may enable identification
Autor:
Hamzah Khawaja, Khurrum Shahzad, Maik Brune, Peter P. Nawroth, Berend Isermann, Ishan Gadi, Marc Freichel, Susanne Gaul, Jes-Niels Boeckel, Saira Ambreen, Angela Wirth, Dagmar Schumacher, Christina Meader, Sameen Fatima, Ulrich Laufs, Rebekka Medert, Jan Haas
ObjectiveAtherosclerosis, the main pathology underlying cardiovascular diseases is accelerated in diabetic patients. Genetic mouse models require breeding efforts which are time-consuming and costly. Our aim was to establish a new nongenetic model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cefa96dad34e8a297689130e90087e54
https://doi.org/10.1101/2021.11.11.468191
https://doi.org/10.1101/2021.11.11.468191
Autor:
Volodymyr Tsvilovskyy, Andreas H. Wagner, Thomas Fleming, Franziska Mohr, Dagmar Schumacher, Ilka Mathar, Kathrin Stilz, Sarah Homberg, Marc Freichel, Robin Sachdeva
Publikováno v:
Cell Calcium. 78:66-75
Methylglyoxal (MG) is a by-product of glucose metabolism and its accumulation has been linked to the development of diabetic complications such as retinopathy and nephropathy by affecting multiple signalling pathways. However, its influence on the in
Autor:
Stephen Wyler, Dagmar Schumacher, Hak Hong Keo, Dai Do Do, Christian Regli, Heinz Schoenhofen, Lorenz Räber, Stefanie Marggi, Nicolas Diehm, Tilmann Moeltgen, Martin C. Schumacher, Yasushi Ueki, Philipp Grimsehl
Publikováno v:
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 26(2)
Purpose: To report the 1-year outcomes of a single-center, all-comers registry aimed to assess effectiveness and safety of endovascular revascularization for atherosclerotic erectile dysfunction (ED) in an unselected patient cohort. Materials and Met
Autor:
Marc Freichel, Dagmar Schumacher, Lutz Birnbaumer, Rebekka Medert, Andreas Draguhn, Alexei V. Egorov
Publikováno v:
Hippocampus. 2019, 29(11)
Hippocampus
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Hippocampus
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Fil: Egorov, Alexei V. Heidelberg University. Institute of Physiology and Pathophysiology; Alemania Fil: Schumacher, Dagmar. Heidelberg University. Institute of Pharmacology; Alemania Fil: Medert, Rebekka. Heidelberg University. Institute of Pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed326ecde04d6c8d6ccc84c064b0192
https://repositorio.uca.edu.ar/handle/123456789/9470
https://repositorio.uca.edu.ar/handle/123456789/9470