Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Dagmar Pich"'
Autor:
Johannes Roessler, Dagmar Pich, Verena Krähling, Stephan Becker, Oliver T. Keppler, Reinhard Zeidler, Wolfgang Hammerschmidt
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2892 (2023)
The successful development of effective viral vaccines depends on well-known correlates of protection, high immunogenicity, acceptable safety criteria, low reactogenicity, and well-designed immune monitoring and serology. Virus-neutralizing antibodie
Externí odkaz:
https://doaj.org/article/ed0cf5c608c74d6ea76230c07a70e471
Autor:
Wen-Hsin Liu, Paulina Mrozek-Gorska, Anna-Katharina Wirth, Tobias Herold, Larissa Schwarzkopf, Dagmar Pich, Kerstin Völse, M. Camila Melo-Narváez, Michela Carlet, Wolfgang Hammerschmidt, Irmela Jeremias
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background Clinically relevant methods are not available that prioritize and validate potential therapeutic targets for individual tumors, from the vast amount of tumor descriptive expression data. Methods We established inducible transgene
Externí odkaz:
https://doaj.org/article/959c31577ec848568d189cab46db5c31
Autor:
Narendran Reguraman, Asma Hassani, Pretty S. Philip, Dagmar Pich, Wolfgang Hammerschmidt, Gulfaraz Khan
Publikováno v:
Vaccines, Vol 11, Iss 3, p 540 (2023)
Epstein–Barr virus (EBV) is etiologically associated with a number of malignant and non-malignant conditions. Thus, a prophylactic vaccine against this virus could help to reduce the burden of many EBV-associated diseases. Previously, we reported t
Externí odkaz:
https://doaj.org/article/21ac2aba6b2d41998467eb93e936990e
Autor:
Ezgi Akidil, Manuel Albanese, Alexander Buschle, Adrian Ruhle, Dagmar Pich, Oliver T Keppler, Wolfgang Hammerschmidt
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009117 (2021)
Gene editing is now routine in all prokaryotic and metazoan cells but has not received much attention in immune cells when the CRISPR-Cas9 technology was introduced in the field of mammalian cell biology less than ten years ago. This versatile techno
Externí odkaz:
https://doaj.org/article/a532f190d5ea453cb33f6fc4c2b5bc26
Autor:
Mickaël Bouvet, Stefanie Voigt, Takanobu Tagawa, Manuel Albanese, Yen-Fu Adam Chen, Yan Chen, Devin N. Fachko, Dagmar Pich, Christine Göbel, Rebecca L. Skalsky, Wolfgang Hammerschmidt
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Acute antiviral functions of all nucleated cells rely on type I interferon (IFN-I) pathways triggered upon viral infection. Host responses encompass the sensing of incoming viruses, the activation of specific transcription factors that induce the tra
Externí odkaz:
https://doaj.org/article/5df41ff7727d458eb1c5cf6678139f31
Autor:
Dagmar Pich, Paulina Mrozek-Gorska, Mickaël Bouvet, Atsuko Sugimoto, Ezgi Akidil, Adam Grundhoff, Stephan Hamperl, Paul D. Ling, Wolfgang Hammerschmidt
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Epstein-Barr virus (EBV) infects and activates resting human B lymphocytes, reprograms them, induces their proliferation, and establishes a latent infection in them. In established EBV-infected cell lines, many viral latent genes are express
Externí odkaz:
https://doaj.org/article/44af517b4c2d4cc5aeabf29c7336daf8
Autor:
Johannes Roessler, Dagmar Pich, Manuel Albanese, Paul R. Wratil, Verena Krähling, Johannes Christian Hellmuth, Clemens Scherer, Michael von Bergwelt-Baildon, Stephan Becker, Oliver T. Keppler, Alain Brisson, Reinhard Zeidler, Wolfgang Hammerschmidt
Publikováno v:
PNAS Nexus 1:pgac045 (2022)
PNAS Nexus
PNAS Nexus
Neutralizing antibodies (NAbs), and their concentration in sera of convalescents and vaccinees are a solid correlate of protection from COVID-19. The antibody concentrations in clinical samples that neutralize SARS-CoV-2 are difficult and very cumber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bf4fb9e456049f2d50580b03f04908
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66662
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66662
Autor:
Alexander Buschle, Thomas Schwarzmayr, Dagmar Pich, Wolfgang Hammerschmidt, Ron Fechtner, Paulina Mrozek-Gorska, Antonio Scialdone
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance More than 50 years ago, Epstein–Barr virus (EBV) was found to infect resting human B lymphocytes and to induce their continuous proliferation in vitro. This seminal finding clearly mimics aspects of EBV’s oncogenic potential in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba8bb76a3ebb0814a992df44ef89f99
https://doi.org/10.1073/pnas.1901314116
https://doi.org/10.1073/pnas.1901314116
Epstein-Barr virus (EBV), a member of the large herpesvirus family is a very complex humanγ-herpesvirus. Its complexity with respect to viral gene regulation, its preferred latent life style and technical difficulties are major obstacles, which hind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f85106b4337c4e1993c8ee0109ccbc7
https://doi.org/10.1101/2021.04.26.439973
https://doi.org/10.1101/2021.04.26.439973
Autor:
Tobias Straub, Alexander Buschle, Filippo M. Cernilogar, Helmut Blum, Stefan Krebs, Andreas Ettinger, Wolfgang Hammerschmidt, Gunnar Schotta, Paulina Mrozek-Gorska, Dagmar Pich, Bianca Mocanu
Publikováno v:
Nucleic Acids Research
Epstein-Barr virus (EBV), a herpes virus also termed HHV 4 and the first identified human tumor virus, establishes a stable, long-term latent infection in human B cells, its preferred host. Upon induction of EBV’s lytic phase, the latently infected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912338cdccdfe373dc78b7dfe7cdce1d
https://pubmed.ncbi.nlm.nih.gov/33675667
https://pubmed.ncbi.nlm.nih.gov/33675667