Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dagmar Oette"'
Autor:
Pierre L. Triozzi, Shailendra Verma, John Holcenberg, James A. Neldhart, David G. Mayernik, Jonathan C. Yau, John Nemunaitis, Dagmar Oette, Ann F. Hayes, Donald Quick
Publikováno v:
American Journal of Hematology. 51:289-295
This is a double-blind randomized placebo-controlled trial to evaluate the efficacy and safety of granulocyte-macrophage colony-stimulating-factor (GM-CSF) after dose-intensive cyclophosphamide, etoposide, and cisplatin (DICEP). Fifty-six patients wi
Autor:
Michael L. Graham, Darell D. Bigner, Beverly Hockenberger, Abbe Sue Rubin, Mark Brown, Herb Fuchs, Joanne Kurtzberg, Gary J. Felsberg, Ruth Fredericks, O. Michael Colvin, Albert Moghrabi, Margaret Duncan-Brown, Dagmar Oette, Henry S. Friedman, Daniel H. Lachance, S. Clifford Schold, Frances Ann Hayes, Barry Golembe, Elizabeth S. Stewart, Iley Browning, Robert D. Tien, Lee Ferrell, Tracy Kerby
Publikováno v:
Medical and Pediatric Oncology. 24:241-247
We conducted a dose escalation trial of cyclophosphamide plus Sargramostim in the therapy of patients with newly diagnosed or recurrent central nervous system tumors. Cyclophosphamide was administered at doses ranging between 1.0 and 2.5 g/m2 daily f
Publikováno v:
International Journal of Immunopharmacology. 16:75-90
The purpose of these studies was to examine the biodistribution and pharmacokinetics of radiolabeled human CHO cell-derived rHuGM-CSF in normal Rhesus monkeys (Macaca mulatta) following intravenous (i.v.) and subcutaneous (s.c.) injection. A dual rad
Autor:
Diane Variakojis, Cheryl A. Arce, Hillard M. Lazarus, Martin M. Oken, Edward G. Mansour, Michael G. Chen, Dagmar Oette, Janet Andersen, Stanton L. Gerson
Publikováno v:
Blood. 78:830-837
Sixteen patients with relapsed non-Hodgkin's lymphoma underwent autologous bone marrow transplantation and infusion of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF). Treatment consisted of involved-field radiotherapy,
Autor:
Lee M. Nadler, Dagmar Oette, C. Dean Buckner, Morris S. Gold, John Nemunaitis, Arnold S. Freedman, Frederick R. Appelbaum, SN Rabinowe, Nicole Onetto, Jerome Ritz, John A. Hansen, Jack W. Singer, S Gillis, James O. Armitage, Julie M. Vose, Philip J. Bierman
Publikováno v:
New England Journal of Medicine. 324:1773-1778
The period of neutropenia after autologous bone marrow transplantation results in substantial morbidity and mortality. The results of previous phase I-II clinical trials suggest that recombinant human granulocyte-macrophage colony-stimulating factor
Autor:
Sharon M. Wahl, Laura E. Shay, James M. Pluda, Samuel Broder, Mary Maha, Charles E. Myers, Robert Yarchoan, Nanette McAtee, Phillip D. Smith, Dagmar Oette
Publikováno v:
Blood. 76:463-472
We investigated the effects of recombinant human granulocyte-macrophage colony-stimulating factor (rGM-CSF) administered by the subcutaneous route, first alone and then alternating with azidothymidine (AZT), in leukopenic patients with severe human i
Autor:
Tracy Kerby, Joanne Kurtzberg, Daniel H. Lachance, S. Clifford Schold, Robert D. Tien, Lee Ferrell, Gary J. Felsberg, Michael L. Graham, Albert Moghrabi, Elizabeth S. Stewart, Herb Fuchs, Margaret Duncan-Brown, O. Michael Colvin, Dagmar Oette, Mark Brown, Darell D. Bigner, Henry S. Friedman, Beverly Hockenberger, Gary J. Allegretta
Publikováno v:
Medical and pediatric oncology. 25(3)
Thirteen patients with recurrent medulloblastoma were treated with cyclophosphamide in association with Sargramostim. Cyclophosphamide was given at doses ranging between 1.0-2.5 g/m2 daily for two doses. Sargramostim was given at a fixed dose of 250
Autor:
Dagmar Oette, Laura Gelpke, Carolyn D. Runowicz, Scott Wadler, Howard W. Bruckner, James L. Speyer, Erin P. Demakos, John Mandeli, Robert C. Wallach, Carmel J. Cohen, James F. Holland, Joan Sorich, Howard S. Hochster, Gary L. Goldberg
Publikováno v:
Gynecologic oncology. 56(3)
The hematopoietic growth factor, recombinant human interleukin-3 (rhu IL-3), stimulates production of both leukocytes and platelets, and thus potentially has greater utility than growth factors that solely stimulate leukocytes production when employe
Autor:
Roy B. Jones, Colleen J. Gilbert, Robert C. Bast, Joanne Kurtzberg, Elizabeth J. Shpall, William P. Peters, Stephen J. Brandt, Susan K. Atwater, Dagmar Oette, Michael J. Borowitz
Publikováno v:
New England Journal of Medicine. 318:869-876
Recombinant human granulocyte-macrophage colony-stimulating factor (rHuGM-CSF) has been reported to increase the leukocyte count in subhuman primates subjected to total-body irradiation and in patients with the acquired immunodeficiency syndrome. We
Publikováno v:
New England Journal of Medicine. 317:593-598
We administered recombinant (biosynthetic) human granulocyte-macrophage colony-stimulating factor (GM-CSF) to 16 patients with the acquired immunodeficiency syndrome (AIDS) and leukopenia (2225 +/- 614 cells per microliter [mean +/- SD]). Each patien