Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Dagmar Meyer, zu Heringdorf"'
Autor:
Shah Alam, Sumaiya Yasmeen Afsar, Maya Anik Wolter, Luisa Michelle Volk, Daniel Nicolae Mitroi, Dagmar Meyer zu Heringdorf, Gerhild van Echten-Deckert
Publikováno v:
Cells, Vol 12, Iss 14, p 1844 (2023)
Astrocytes are critical players in brain health and disease. Brain pathologies and lesions are usually accompanied by astroglial alterations known as reactive astrogliosis. Sphingosine 1-phosphate lyase (SGPL1) catalysis, the final step in sphingolip
Externí odkaz:
https://doaj.org/article/08f9df6a206044d48bc12ef5a27d545d
Autor:
Gergely Imre, Verena Krähling, Madeleine Eichler, Sandra Trautmann, Nerea Ferreirós, M. Javad Aman, Fatah Kashanchi, Krishnaraj Rajalingam, Stefan Pöhlmann, Stephan Becker, Dagmar Meyer zu Heringdorf, Josef Pfeilschifter
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102266- (2021)
Summary: Ebola virus (EBOV) is responsible for outbreaks with case fatality rates of up to 90% and for an epidemic in West Africa with more than ten thousand deaths. EBOV glycoprotein (EBOV-GP) is the only viral surface protein and is responsible for
Externí odkaz:
https://doaj.org/article/a4d3b8fd63584eefb7be8371826ef0f5
Autor:
Thomas Pleli, Antonia Mondorf, Nerea Ferreiros, Dominique Thomas, Karel Dvorak, Ricardo M. Biondi, Dagmar Meyer zu Heringdorf, Stefan Zeuzem, Gerd Geisslinger, Herbert Zimmermann, Oliver Waidmann, Albrecht Piiper
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 6, Pp 2516-2528 (2018)
Background/Aims: Signaling of Gs protein-coupled receptors (GsPCRs) is accomplished by stimulation of adenylyl cyclase, causing an increase of the intracellular cAMP concentration, activation of the intracellular cAMP effectors protein kinase A (PKA)
Externí odkaz:
https://doaj.org/article/0a4e904e6a144be5903bf729f11e5b78
Autor:
Kira Vanessa Blankenbach, Ralf Frederik Claas, Natalie Judith Aster, Anna Katharina Spohner, Sandra Trautmann, Nerea Ferreirós, Justin L. Black, John J. G. Tesmer, Stefan Offermanns, Thomas Wieland, Dagmar Meyer zu Heringdorf
Publikováno v:
Cells, Vol 9, Iss 10, p 2201 (2020)
Diverse extracellular signals induce plasma membrane translocation of sphingosine kinase-1 (SphK1), thereby enabling inside-out signaling of sphingosine-1-phosphate. We have shown before that Gq-coupled receptors and constitutively active Gαq/11 spe
Externí odkaz:
https://doaj.org/article/f549208b4be8498faf967cdaab7c6069
Autor:
Katja Ihlefeld, Hans Vienken, Ralf Frederik Claas, Kira Blankenbach, Agnes Rudowski, Michael ter Braak, Alexander Koch, Paul P. Van Veldhoven, Josef Pfeilschifter, Dagmar Meyer zu Heringdorf
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 1, Pp 60-69 (2015)
Sphingosine 1-phosphate (S1P) is an extra- and intracellular mediator that regulates cell growth, survival, migration, and adhesion in many cell types. S1P lyase is the enzyme that irreversibly cleaves S1P and thereby constitutes the ultimate step in
Externí odkaz:
https://doaj.org/article/f071ef55eb7d497a8e684309cb0a5c67
Autor:
Dagmar Meyer zu Heringdorf, Corina Ratiu, Amro Elgheznawy, Voahanginirina Randriamboavonjy, Anastasia Kyselova, Ingrid Fleming, Mauro Siragusa, Alexander W. Mann, Beate Fisslthaler, Fredy Delgado Lagos
Publikováno v:
Blood. 137:1641-1651
Secreted modular calcium-binding protein 1 (SMOC1) is an osteonectin/SPARC-related matricellular protein, whose expression is regulated by microRNA-223 (miR-223). Given that platelets are rich in miR-223, this study investigated the expression of SMO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcf0b32aeb935a44038d5325894fca8
https://doi.org/10.1182/blood.2020009405
https://doi.org/10.1182/blood.2020009405
Autor:
Robert Brunkhorst, Sandra Trautmann, Dagmar Meyer zu Heringdorf, Rajkumar Vutukuri, Yannick Schreiber, Josef Pfeilschifter, Dominique Thomas, Waltraud Pfeilschifter, Alexander Koch, Franziska Mayser
Publikováno v:
The FASEB Journal. 34:3932-3942
Sphingosine 1-phosphate (S1P) signaling influences numerous cell biological mechanisms such as differentiation, proliferation, survival, migration, and angiogenesis. Intriguingly, our current knowledge is based solely on the role of S1P with an 18-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::672ac02508af3c91111d2627b84f7c2d
https://doi.org/10.1096/fj.201902391r
https://doi.org/10.1096/fj.201902391r
Autor:
Guenter Schultz, Peter Gierschik, Dagmar Meyer zu Heringdorf, Klaus Aktories, Thomas Wieland, Martina Schmidt
Publikováno v:
Naunyn-Schmiedebergs Archives of Pharmacology. 392(8):887-911
Karl H. Jakobs, former editor-in-chief of Naunyn-Schmiedeberg's Archives of Pharmacology and renowned molecular pharmacologist, passed away in April 2018. In this article, his scientific achievements regarding G protein-mediated signal transduction a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee0168eaad3ca10efa35ed328b817a7
https://hdl.handle.net/11370/0e90105a-8fa8-4446-b59c-7e63d0ed34d5
https://hdl.handle.net/11370/0e90105a-8fa8-4446-b59c-7e63d0ed34d5
Autor:
M. Javad Aman, Nerea Ferreirós, Dagmar Meyer zu Heringdorf, Fatah Kashanchi, Josef Pfeilschifter, Sandra Trautmann, Gergely Imre, Krishnaraj Rajalingam, Madeleine Eichler, Stefan Pöhlmann, Verena Krähling, Stephan Becker
Publikováno v:
iScience
iScience, Vol 24, Iss 4, Pp 102266-(2021)
iScience, Vol 24, Iss 4, Pp 102266-(2021)
Summary Ebola virus (EBOV) is responsible for outbreaks with case fatality rates of up to 90% and for an epidemic in West Africa with more than ten thousand deaths. EBOV glycoprotein (EBOV-GP) is the only viral surface protein and is responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae22327c1ed6e75d912268851ef81498
http://europepmc.org/articles/PMC8005759
http://europepmc.org/articles/PMC8005759
