Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dagmar Bury"'
Autor:
Rianne de Ligt, Joost Westerhout, Dimitri Grossouw, Thomas P Buters, Robert Rissmann, Jacobus Burggraaf, Albert D Windhorst, Sarah Tozer, Gerlinde Pappa, Brian Wall, Dagmar Bury, David R Mason, Wouter H J Vaes
Publikováno v:
Toxicology Research. 11:511-519
A follow-up study was performed in 12 healthy women to evaluate systemic exposure to aluminium following topical application of a representative antiperspirant formulation under real-life use conditions (part A) and to assess the local fate of topica
Autor:
Sebastian Hoffmann, Nathalie Alépée, Nicola Gilmour, Petra S. Kern, Erwin van Vliet, Fanny Boislève, Dagmar Bury, Elodie Cloudet, Martina Klaric, Jochen Kühnl, Jon F. Lalko, Karsten Mewes, Masaaki Miyazawa, Hayato Nishida, Mai Thanh Tam Brami, Mustafa Varçin, Anne Marie Api, Cosmetics Europe
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 131
The assessment of skin sensitisation is a key requirement in all regulated sectors, with the European Union's regulation of cosmetic ingredients being most challenging, since it requires quantitative skin sensitisation assessment based on new approac
Autor:
Rianne, de Ligt, Joost, Westerhout, Dimitri, Grossouw, Thomas P, Buters, Robert, Rissmann, Jacobus, Burggraaf, Albert D, Windhorst, Sarah, Tozer, Gerlinde, Pappa, Brian, Wall, Dagmar, Bury, David R, Mason, Wouter H J, Vaes
Publikováno v:
Toxicology research. 11(3)
A follow-up study was performed in 12 healthy women to evaluate systemic exposure to aluminium following topical application of a representative antiperspirant formulation under real-life use conditions (part A) and to assess the local fate of topica
Publikováno v:
Toxicology Letters. 350:S220-S221
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 123
The Threshold of Toxicological Concern (TTC) is an internationally accepted pragmatic and conservative tool for the safety assessment of substances, which is used in a wide range of regulatory contexts. The TTC approach produces human exposure thresh
Autor:
Gladys Ouedraogo, Camilla Alexander-White, Dagmar Bury, Harvey J. Clewell, Mark Cronin, Tom Cull, Matthew Dent, Bertrand Desprez, Ann Detroyer, Corie Ellison, Stefania Giammanco, Eric Hack, Nicola J. Hewitt, Gerry Kenna, Martina Klaric, Reinhard Kreiling, Cathy Lester, Catherine Mahony, Enrico Mombelli, Jorge Naciff, John O'Brien, Andreas Schepky, Sarah Tozer, Bart van der Burg, Barbara van Vugt-Lussenburg, Sharon Stuard, null Cosmetics Europe
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 132
Parabens are esters of para-hydroxybenzoic acid that have been used as preservatives in many types of products for decades including agrochemicals, pharmaceuticals, food and cosmetics. This illustrative case study with propylparaben (PP) demonstrates
Autor:
Bertrand Desprez, Alicia Paini, Nicola J. Hewitt, Catherine Mahony, Mark T. D. Cronin, Cathy Lester, Eric Hack, Gerry Kenna, Andreas Schepky, James W. Firman, Alina Efremenko, Harvey J. Clewell, Martina Klaric, Camilla Alexander-White, Cosmetics Europe, Dagmar Bury, Ann Detroyer, Gladys Ouedraogo
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 123
This case study on the model substance caffeine demonstrates the viability of a 10-step read-across (RAX) framework in practice. New approach methodologies (NAM), including RAX and physiologically-based kinetic (PBK) modelling were used to assess the
Autor:
Nathalie Alépée, Dirk Petersohn, Sebastian Hoffmann, Elodie Clouet, Petra S. Kern, Martina Klaric, Jochen Kühnl, Hayato Nishida, Dagmar Bury, Morihiko Hirota, Erwin van Vliet, Masaaki Miyazawa, Nicola Gilmour, Anne Osmani, Karsten Rüdiger Mewes, Shuichi Sekine, Fanny Boisleve, Jon F. Lalko
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 116
All cosmetic products placed onto the market must undergo a risk assessment for human health to ensure they are safe for consumers, including an assessment of skin sensitisation risk. Historically, in vivo animal test methods were used to identify an
Autor:
J Wong, R Labib, Dagmar Bury, M Leal, Gary Eichenbaum, Jorge M. Naciff, Fanny Boisleve, S Girard
Publikováno v:
Regulatory Toxicology and Pharmacology. 94:245-251
Salicylic acid (SA) has a long history of safe use as ingredient in topical cosmetic products. In 2016, the Committee for Risk Assessment of the European Chemicals Agency proposed to classify SA as a Category 2 reproductive toxicant based on adverse
Autor:
Dagmar Bury, Erwin van Vliet, Nathalie Alépée, Hind Assaf Vandecasteele, Françoise Gautier, Fleur Tourneix
Publikováno v:
Regulatory Toxicology and Pharmacology. 123:104936
Skin sensitisation is a key adverse health effect to be addressed in the safety assessment of cosmetic ingredients. Regulatory demands have urged the development of Next Generation Risk Assessment (NGRA) using New Approach Methodologies (NAM) and Def