Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dagmar Blöcker"'
Autor:
Luciana Berod, Dagmar Blöcker, Klaus Aktories, Marco Idzko, Joachim W. Fluhr, Johannes Norgauer, Joachim H. C. Orth
Publikováno v:
International Immunology. 18:459-464
Dendritic cells (DCs) are considered as one of the principal initiators of immune responses. In their immature state, they migrate into peripheral tissue in order to uptake antigen and to patrol for danger signals. Upon maturation, they acquire the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8cdbce82dfa66e858bf9f429d70674
https://doi.org/10.1093/intimm/dxh386
https://doi.org/10.1093/intimm/dxh386
Autor:
Dagmar Blöcker, Kathrin Pohlmann, Christoph Bachmeyer, Gerd Haug, Klaus Aktories, Holger Barth, Roland Benz
Publikováno v:
Journal of Biological Chemistry. 278:37360-37367
The binary Clostridium botulinum C2 toxin consists of two individual proteins, the transport component C2II (80 kDa) and the enzyme component C2I, which ADP-ribosylates G-actin in the cytosol of cells. Trypsin-activated C2II (C2IIa) forms heptamers t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d167fb1b8c6156d8f0ff2ab32e86a1a1
https://doi.org/10.1074/jbc.m305849200
https://doi.org/10.1074/jbc.m305849200
The C Terminus of Component C2II of Clostridium botulinum C2 Toxin Is Essential for Receptor Binding
Publikováno v:
Infection and Immunity. 68:4566-4573
The binary Clostridium botulinum C2 toxin consists of two separate proteins, the binding component C2II (80.5 kDa) and the actin-ADP-ribosylating enzyme component C2I (49.4 kDa). For its cytotoxic action, C2II binds to a cell membrane receptor and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9248f15e73bec5431f098761f5d4ea23
https://doi.org/10.1128/iai.68.8.4566-4573.2000
https://doi.org/10.1128/iai.68.8.4566-4573.2000
Publikováno v:
Biochemistry. 42(18)
The binding component (C2II) of the binary Clostridium botulinum C2 toxin mediates transport of the actin ADP-ribosylating enzyme component (C2I) into the cytosol of target cells. C2II (80 kDa) is activated by trypsin cleavage, and proteolytically ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f02644051c9086d2e0523b27cc0a03
https://pubmed.ncbi.nlm.nih.gov/12731878
https://pubmed.ncbi.nlm.nih.gov/12731878
Publikováno v:
Biochemistry. 42(17)
Pasteurella multocida produces a 146-kDa protein toxin (PMT), which activates multiple cellular signal-transduction pathways, resulting in the activation of PLCbeta, Rho, JNK, and ERK. In addition to an essential cysteine residue at position 1165, PM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc46222281bd649c326c04ecef7620e
https://pubmed.ncbi.nlm.nih.gov/12718539
https://pubmed.ncbi.nlm.nih.gov/12718539
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 40(8)
Clostridium botulinum C2 enterotoxin consists of two unlinked proteins designated as C2II, which recognizes a cell-surface glycoprotein and translocates an ADP-ribosyltransferase, C2I, into the cytosol of a targeted cell. Fluorescence-activated cytom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c55fc54e8543ff21d4149f61b1eecf
https://pubmed.ncbi.nlm.nih.gov/12165316
https://pubmed.ncbi.nlm.nih.gov/12165316
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 366(6)
Several bacterial protein toxins, including Clostridium botulinum C2 toxin, Clostridum perfringens iota toxin, Clostridium difficile ADP-ribosyltransferase, and the Bacillus-produced vegetative insecticidal proteins, target the cytoskeleton by ADP-ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374b394b8c1494b4a02ac0667c7b4f60
https://pubmed.ncbi.nlm.nih.gov/12444490
https://pubmed.ncbi.nlm.nih.gov/12444490
Publikováno v:
Infection and immunity. 69(5)
The binary iota-toxin is produced by Clostridium perfringens type E strains and consists of two separate proteins, the binding component iota b (98 kDa) and an actin-ADP-ribosylating enzyme component iota a (47 kDa). Iota b binds to the cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc643f4872d9a893ad301d3ca9da380
https://pubmed.ncbi.nlm.nih.gov/11292715
https://pubmed.ncbi.nlm.nih.gov/11292715
Autor:
Dagmar Blöcker, Joachim Behlke, Klaus Aktories, Holger Barth, Wilma Bergsma-Schutter, Roland Benz, Alain Brisson
Publikováno v:
The Journal of Biological Chemistry, 275(25), 18704-18711. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
The actin-ADP-ribosylating binary Clostridium botulinum C2 toxin consists of two individual proteins, the binding/translocation component C2II and the enzyme component C2I. To elicit its cytotoxic action, C2II binds to a receptor on the cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33956bfd71e1bbe587540d66692a3a4b
https://research.rug.nl/en/publications/eeb64556-b38f-466d-8927-94da56c30005
https://research.rug.nl/en/publications/eeb64556-b38f-466d-8927-94da56c30005
Publikováno v:
The Plant journal : for cell and molecular biology. 21(2)
The Chlamydomonas reinhardtii HSP70A promoter can be induced by both heat shock and light. Several characteristics of this promoter suggest its usefulness as a tool for improved transgene expression in this alga. (i) It may by itself confer high indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d2068a21df379969cb83ee1910b50c
https://pubmed.ncbi.nlm.nih.gov/10743653
https://pubmed.ncbi.nlm.nih.gov/10743653