Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Dagmar, Simon"'
Autor:
Christina Bürgler, Danielle Dutoit, Susanne Radonjic‐Hoesli, Kathrin Thormann, Mathias Lehmann, Shida Yousefi, Hans‐Uwe Simon, Dagmar Simon
Publikováno v:
JEADV Clinical Practice, Vol 3, Iss 2, Pp 478-486 (2024)
Abstract Background Atopic dermatitis (AD) is characterized by skin barrier dysfunction and immune dysregulation. Autophagy, which is important for the epidermal differentiation, is impaired in AD. The treatment with dupilumab, an interleukin (IL)‐
Externí odkaz:
https://doaj.org/article/6a435cace1b1481c9e2f281e6735c8c8
Autor:
Nicole L. Bertschi, Oliver Steck, Fabian Luther, Cecilia Bazzini, Leonhard von Meyenn, Stefanie Schärli, Angela Vallone, Andrea Felser, Irene Keller, Olivier Friedli, Stefan Freigang, Nadja Begré, Susanne Radonjic-Hoesli, Cristina Lamos, Max Philip Gabutti, Michael Benzaquen, Markus Laimer, Dagmar Simon, Jean-Marc Nuoffer, Christoph Schlapbach
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract T helper 9 (TH9) cells promote allergic tissue inflammation and express the type 2 cytokines, IL-9 and IL-13, as well as the transcription factor, PPAR-γ. However, the functional role of PPAR-γ in human TH9 cells remains unknown. Here, we
Externí odkaz:
https://doaj.org/article/19e9bace06d847ceba581b56d780dbb5
Autor:
Hélène Aubert, Kathrin Thormann, Sebastien Barbarot, Pavel Chernyshov, Meete Deleuran, Maya El‐Hachem, Jette deGroot, Danielle Marcoux, Dagmar Simon, Florine Raymakers, Jean‐François Stalder
Publikováno v:
JEADV Clinical Practice, Vol 1, Iss 2, Pp 144-149 (2022)
Abstract Background Atopic dermatitis (AD) is a chronic inflammatory skin condition that has a major impact on the quality of life of patients and their families. Therapeutic patient education (TPE) is recommended for all patients with this condition
Externí odkaz:
https://doaj.org/article/7f9d962c5fa24d26a65e8d5d556617b1
Autor:
Kim Klapan, Dagmar Simon, Alexander Karaulov, Marina Gomzikova, Albert Rizvanov, Shida Yousefi, Hans-Uwe Simon
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Autophagy is a highly conserved lysosomal degradation system that involves the creation of autophagosomes, which eventually fuse with lysosomes and breakdown misfolded proteins and damaged organelles with their enzymes. Autophagy is widely known for
Externí odkaz:
https://doaj.org/article/c02be37c36e4406fb64be11551d1d7f1
Autor:
Yan Guex-Crosier, Julie Di-Lucca, Peter Häusermann, Emmanuel Laffitte, Ieva Saulite, Peter Schmid-Grendelmeier, Kaspar Schürch, Kathrin Thormann, Dagmar Simon
Publikováno v:
Swiss Medical Weekly, Vol 151, Iss 3334 (2021)
Atopic dermatitis is a chronic inflammatory skin disease characterised by eczematous skin lesions and intense pruritus. It is often associated with other atopic diseases such as allergic rhinitis and conjunctivitis, bronchial asthma and eosinophilic
Externí odkaz:
https://doaj.org/article/fb9ba93a0d4148c590c7f22cf4947a1f
Autor:
S. Morteza Seyed Jafari, Laurence Feldmeyer, Simon Bossart, Dagmar Simon, Christoph Schlapbach, Luca Borradori
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Bullous pemphigoid (BP) is a blistering autoimmune skin disease. Omalizumab, a monoclonal antibody directed to IgE, showed a beneficial effect in treatment of recalcitrant BP in case series. More recently, dupilumab, an interleukin (IL)-4-receptor al
Externí odkaz:
https://doaj.org/article/349ff6b3fdc6461e90808f2d2c70e839
Autor:
Mathias Lehmann, Simone Cazzaniga, Dagmar Simon, Delphine L. Perruchoud, Luca Borradori, Anna Rammlmair
Publikováno v:
Acta Dermato-Venereologica, Vol 100, Iss 4, p adv00068 (2020)
Chronic pruritus profoundly affects patients’ quality of life. The objective of this retrospective cross-sectional study was to characterize patients with chronic pruritus and identify patterns, in order to delineate a better diagnostic approach. B
Externí odkaz:
https://doaj.org/article/7bbd8e8900414ca7adcb12a02d478f75
Autor:
Simone Cazzaniga, Christina Wiedmer, Živa Frangež, Maziar Shafighi, Helmut Beltraminelli, Benedikt Weber, Dagmar Simon, Luigi Naldi, Hans-uwe Simon, Robert E. Hunger, S. Morteza Seyed Jafari
Publikováno v:
Acta Dermato-Venereologica, Vol 100, Iss 1, p adv00019 (2020)
Abstract is missing (Short communication)
Externí odkaz:
https://doaj.org/article/336436cb50f34fc092c6a038bfbfbd1e
Autor:
Peter Valent, Amy D. Klion, Florence Roufosse, Dagmar Simon, Georgia Metzgeroth, Kristin M. Leiferman, Juliana Schwaab, Joseph H. Butterfield, Wolfgang R. Sperr, Karl Sotlar, Peter Vandenberghe, Gregor Hoermann, Torsten Haferlach, Richard Moriggl, Tracy I. George, Cem Akin, Bruce S. Bochner, Jason Gotlib, Andreas Reiter, Hans‐Peter Horny, Michel Arock, Hans‐Uwe Simon, Gerald J. Gleich
Publikováno v:
Allergy. 78:47-59
Eosinophilia and eosinophil activation are recurrent features in various reactive states and certain hematologic malignancies. In patients with hypereosinophilia (HE), HE-induced organ damage is often encountered and may lead to the diagnosis of a hy
Autor:
Sébastien Holvoet, Sophie Nutten, Lénaïck Dupuis, Dominique Donnicola, Tristan Bourdeau, Betsy Hughes-Formella, Dagmar Simon, Hans-Uwe Simon, Ryan S. Carvalho, Jonathan M. Spergel, Sibylle Koletzko, Carine Blanchard
Publikováno v:
Nutrients, Vol 13, Iss 9, p 3113 (2021)
Specific partially hydrolysed whey-based infant formulas (pHF-W) have been shown to decrease the risk of atopic dermatitis (AD) in infants. Historically, AD has been associated primarily with milk allergy; however, defective skin barrier function can
Externí odkaz:
https://doaj.org/article/65cca7d3a7e34ddfb8606637b3d43f85