Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dagfinn Ekse"'
Autor:
Nhat K. Duong, Yngve Nordbø, Dagfinn Ekse, Hilgegunn Helle, Per Eystein Lønning, Turid Aas, Jürgen Geisler, Dean B. Evans
Publikováno v:
Clinical Cancer Research. 14:6330-6335
Purpose: To evaluate the influence of the third-generation aromatase inhibitor letrozole (Femara) on breast cancer tissue levels of estrone (E1), estradiol (E2), and estrone sulfate (E1S) in postmenopausal women undergoing primary treatment for local
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 109:90-95
Following the introduction of potent aromatase inhibitors for the treatment of breast cancer patients, highly sensitive methods have become mandatory to evaluate the influence of these drugs on plasma estrogen levels. Commercially available kits for
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 104:27-34
The adipocytokine leptin has recently been shown to enhance the expression of aromatase via promoter II and I.3 using an AP-1 motif. Thus, we evaluated the correlation between plasma leptin concentrations and total body aromatization (TBA) as well as
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 81:95-102
Plasma insulin-like growth factor (IGF)-I, free IGF-I and -II, IGF-binding protein (IGFBP)-1, -2, and -3 together with IGFBP-3 protease activity were measured in 114 postmenopausal and 39 premenopausal healthy women. For each parameter, the mathemati
Autor:
Stig S. Frøland, Dagfinn Ekse, P Aukrust, Jeffrey M P Holly, Per Eystein Lønning, Thor Ueland, S.I. Helle
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:227-233
Endocrine dysfunctions have previously been reported in human immunodeficiency virus (HIV) infection. In this study we evaluated the relation of immunological parameters, virus load, clinical stage, and wasting to several parameters of the insulin-li
Publikováno v:
Journal of Endocrinology. 162:265-270
The aim of this study was to determine the impact of the administration route and cigarette smoking on plasma oestrogen levels during oral and parenteral oestrogen replacement therapy (ERT). Fourteen healthy postmenopausal women (six smokers and eigh
Autor:
S.I. Helle, Dagfinn Ekse, Per Eystein Lønning, Jeffrey M P Holly, S Lundgren, Stephanie Geisler
Publikováno v:
European Journal of Cancer. 35:1070-1075
This study was designed to evaluate time and dose dependency of alterations in insulin-like growth factor (IGF)-I, free IGF-I and the functional status of IGF-binding protein (IGFBP)-3 in breast cancer patients during treatment with megestrol acetate
Autor:
Svein Inge Helle, Jeffrey M P Holly, Walter Jonat, Dagfinn Ekse, Per Eystein Lønning, Marius Giurescu
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 66:159-163
The influence of the novel antiprogestin onapristone on the serum insulin-like growth factor (IGF) system was studied in a group of 13 postmenopausal women with metastatic breast cancer. Blood samples were obtained before treatment and subsequently a
Autor:
Asbjørn Svardal, Rolf K. Berge, Dagfinn Ekse, Bjørn Netteland, Dag Clement Johannessen, Per Eystein Lønning, Hildegunn Berntsen
Publikováno v:
Cancer Chemotherapy and Pharmacology. 42:46-52
Purpose: Elevated cellular glutathione has been associated with resistance to cancer chemotherapy. Treatment with the aromatase inhibitor aminoglutethimide increases the concentration of γ-glutamyl transpeptidase (γ-GT) in breast cancer patients. T
Autor:
Per Eystein Lønning, Ernst A. Lien, Dag Clement Johannessen, Theodore Fotsis, Dagfinn Ekse, Herman Adlercreutz
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 52:491-496
Estrone sulphate (E1S) may be an important estrogen source in breast cancers, particularly in postmenopausal women. Recent studies have shown that tamoxifen inhibits the uptake and metabolism of E1S to estradiol (E2) in cell cultures. To evaluate a p