Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Dag H, Yasui"'
Autor:
Osman Sharifi, Viktoria Haghani, Kari E. Neier, Keith J. Fraga, Ian Korf, Sophia M. Hakam, Gerald Quon, Nelson Johansen, Dag H. Yasui, Janine M. LaSalle
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Dominant X-linked diseases are uncommon due to female X chromosome inactivation (XCI). While random XCI usually protects females against X-linked mutations, Rett syndrome (RTT) is a female neurodevelopmental disorder caused by heterozygous M
Externí odkaz:
https://doaj.org/article/27f2deea1c084c859913e45acdf66dda
Autor:
Yihui Zhu, J. Antonio Gomez, Benjamin I. Laufer, Charles E. Mordaunt, Julia S. Mouat, Daniela C. Soto, Megan Y. Dennis, Kelly S. Benke, Kelly M. Bakulski, John Dou, Ria Marathe, Julia M. Jianu, Logan A. Williams, Orangel J. Gutierrez Fugón, Cheryl K. Walker, Sally Ozonoff, Jason Daniels, Luke P. Grosvenor, Heather E. Volk, Jason I. Feinberg, M. Daniele Fallin, Irva Hertz-Picciotto, Rebecca J. Schmidt, Dag H. Yasui, Janine M. LaSalle
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-32 (2022)
Abstract Background Autism spectrum disorder (ASD) involves complex genetics interacting with the perinatal environment, complicating the discovery of common genetic risk. The epigenetic layer of DNA methylation shows dynamic developmental changes an
Externí odkaz:
https://doaj.org/article/f6d35ff30916481bbb358c37ec11e956
Autor:
Kari Neier, Tianna E. Grant, Rebecca L. Palmer, Demario Chappell, Sophia M. Hakam, Kendra M. Yasui, Matt Rolston, Matthew L. Settles, Samuel S. Hunter, Abdullah Madany, Paul Ashwood, Blythe Durbin-Johnson, Janine M. LaSalle, Dag H. Yasui
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Using a mouse model for Rett syndrome (RTT), Neier et al analyze gut microbiome and metabolome profiles during disease progression. They show that pathophysiology and progression of RTT is different in females than in males and suggest that changes i
Externí odkaz:
https://doaj.org/article/c1d9cbe8712d4cf99e5108bdab6417d3
Autor:
Mojgan Rastegar, Dag H. Yasui
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/5c0db84a2c70403a9cea49e26e1ac9ae
Autor:
Osman Sharifi, Dag H. Yasui
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
MeCP2 protein, encoded by the MECP2 gene, binds to DNA and affects transcription. Outside of this activity the true range of MeCP2 function is still not entirely clear. As MECP2 gene mutations cause the neurodevelopmental disorder Rett syndrome in 1
Externí odkaz:
https://doaj.org/article/8e8c306469344f8f9e1ba6464607965e
Autor:
Rochelle L. Coulson, Dag H. Yasui, Keith W. Dunaway, Benjamin I. Laufer, Annie Vogel Ciernia, Yihui Zhu, Charles E. Mordaunt, Theresa S. Totah, Janine M. LaSalle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Many genes have oscillating gene expression pattern in circadian centers of the brain. This study shows cortical diurnal DNA methylation oscillation in a mouse model of Prader-Willi syndrome, and describes corresponding changes in gene expression and
Externí odkaz:
https://doaj.org/article/d481882ef53445478adf7400b2b40b3f
Autor:
Annie Vogel Ciernia, Benjamin I . Laufer, Keith W. Dunaway, Charles E. Mordaunt, Rochelle L. Coulson, Theresa S. Totah, Danielle S. Stolzenberg, Jaime C. Frahm, Akanksha Singh-Taylor, Tallie Z. Baram, Janine M. LaSalle, Dag H. Yasui
Publikováno v:
Epigenetics, Vol 13, Iss 3, Pp 318-330 (2018)
Augmented maternal care during the first postnatal week promotes life-long stress resilience and improved memory compared with the outcome of routine rearing conditions. Recent evidence suggests that this programming commences with altered synaptic c
Externí odkaz:
https://doaj.org/article/227c1ee5f52246338f871058fd440733
Autor:
H. Tomas Rube, Wooje Lee, Miroslav Hejna, Huaiyang Chen, Dag H. Yasui, John F. Hess, Janine M. LaSalle, Jun S. Song, Qizhi Gong
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
MeCP2 is critical for proper brain development, and mutations in the gene encoding MeCP2 are responsible for several neurological disorders. Here, the authors show that the previously reported genome-wide preference of MeCP2 to methylated CpGs is in
Externí odkaz:
https://doaj.org/article/1be597bf744b49939e33398defbd03c2
Autor:
Benjamin I. Laufer, Kari Neier, Anthony E. Valenzuela, Dag H. Yasui, Rebecca J. Schmidt, Pamela J. Lein, Janine M. LaSalle
Publikováno v:
Cell reports, vol 38, iss 9
Polychlorinated biphenyls (PCBs) are developmental neurotoxicants implicated as environmental risk factors for neurodevelopmental disorders (NDDs). Here, we report the effects of prenatal exposure to a human-relevant mixture of PCBs on the DNA methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820205b6b7beba254c576515d3a64d52
https://escholarship.org/uc/item/93q4g7z7
https://escholarship.org/uc/item/93q4g7z7
Autor:
Malaika K. Singleton, Michael L. Gonzales, Karen N. Leung, Dag H. Yasui, Diane I. Schroeder, Keith Dunaway, Janine M. LaSalle
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 1, Pp 190-200 (2011)
Mutations in MECP2, encoding methyl CpG binding protein 2, cause the neurodevelopmental disorder Rett syndrome. MeCP2 is an abundant nuclear protein that binds to chromatin and modulates transcription in response to neuronal activity. Prior studies o
Externí odkaz:
https://doaj.org/article/74a7c1dbf40a48d98acaa0ac631b3437