Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Dag, Kvale"'
Autor:
Erik E. Christensen, MD, Christian H. Prebensen, MD, PhD, Anders B. Martinsen, MD, Elisabeth T. Stiff, MD, Rune Hoff, PhD, Dag Kvale, MD, PhD, Aleksander R. Holten, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 2, p e0865 (2023)
IMPORTANCE:. The Sequential Organ Failure Assessment (SOFA) was chosen in the definition of sepsis due to superior validity in predicting mortality. However, few studies have assessed the contributions of acute versus chronic organ failures to SOFA f
Externí odkaz:
https://doaj.org/article/5a4563793f4241198ac336db42e144c1
Autor:
Synne Jenum, Kristian Tonby, Corina S. Rueegg, Morten Rühwald, Max P. Kristiansen, Peter Bang, Inge Christoffer Olsen, Kjersti Sellæg, Kjerstin Røstad, Tehmina Mustafa, Kjetil Taskén, Dag Kvale, Rasmus Mortensen, Anne Ma Dyrhol-Riise
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Modulating the host immune response during tuberculosis is an emerging and critical advance in the therapeutic approach. Here the authors present data from a first-in-human phase I/II randomised trial on the safety and immunogenicity of adjuvant ther
Externí odkaz:
https://doaj.org/article/6152a3f5e03b4794a0706ed5b7ac2925
Autor:
Magnus Nakrem Lyngbakken, Jan-Erik Berdal, Arne Eskesen, Dag Kvale, Inge Christoffer Olsen, Corina Silvia Rueegg, Anbjørg Rangberg, Christine Monceyron Jonassen, Torbjørn Omland, Helge Røsjø, Olav Dalgard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
The use of hydroxychloroquine therapy for the treatment of Covid-19 is controversial. In this study, Lyngbakken and colleagues present a randomized controlled trial and show that the drug has no antiviral effects in humans infected with SARS-CoV-2.
Externí odkaz:
https://doaj.org/article/d3e72cbb573e47909cf5b6e5c246708b
Autor:
Kristina Berg Lorvik, Malin Holm Meyer-Myklestad, Kushi Kushekar, Charlotte Handeland, Asle Wilhelm Medhus, Marius Lund-Iversen, Birgitte Stiksrud, Dag Kvale, Anne Margarita Dyrhol-Riise, Kjetil Taskén, Dag Henrik Reikvam
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunological non-responders (INR), a subgroup of people living with HIV (PLHIV) who fail to restore CD4+ T cell numbers upon effective antiretroviral treatment, have impaired gut mucosal barrier function and an inferior clinical prognosis compared w
Externí odkaz:
https://doaj.org/article/9df62af0fa0d4195b225b656ba0cd620
Autor:
Magnus Nakrem Lyngbakken, Jan-Erik Berdal, Arne Eskesen, Dag Kvale, Inge Christoffer Olsen, Anbjørg Rangberg, Christine Monceyron Jonassen, Torbjørn Omland, Helge Røsjø, Olav Dalgard
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-3 (2020)
Abstract Objectives The hypothesis of the study is that treatment with hydroxychloroquine sulphate in hospitalised patients with coronavirus disease 2019 (Covid-19) is safe and will accelerate the virological clearance rate for patients with moderate
Externí odkaz:
https://doaj.org/article/ae5f1400634e40a7a8e3abf405e5033d
Autor:
Marthe Jøntvedt Jørgensen, Kristin G. Nore, Hans Christian D. Aass, Emilie Layre, Jérôme Nigou, Rasmus Mortensen, Kjetil Tasken, Dag Kvale, Synne Jenum, Kristian Tonby, Anne Ma Dyrhol-Riise
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
IntroductionEicosanoids and intracellular signaling pathways are potential targets for host-directed therapy (HDT) in tuberculosis (TB). We have explored the effect of cyclooxygenase 2 inhibitor (COX-2i) treatment on eicosanoid levels and signaling p
Externí odkaz:
https://doaj.org/article/7d41700b992d4a0ebe9b7ff00b18c9b4
Autor:
Erik K. Amundsen, PhD, Christina Binde, MD, Erik E. Christensen, MD, Olav Klingenberg, PhD, Dag Kvale, PhD, Aleksander R. Holten, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 7, p e0490 (2021)
OBJECTIVES:. Increase of nucleated RBCs in peripheral blood has been shown to be predictive of mortality in ICU patients. The aim of this study was to explore the prognostic value of nucleated RBCs in the first blood sample taken at admission to the
Externí odkaz:
https://doaj.org/article/a8499630fbb643df9db0e79e754e4d4b
Autor:
Erik E, Christensen, Christina, Binde, Marianne, Leegaard, Kristian, Tonby, Anne-Ma, Dyrhol-Riise, Dag, Kvale, Erik K, Amundsen, Aleksander R, Holten
Publikováno v:
Shock
Background: Biomarkers for early recognition of infection are warranted. The hypothesis of this study was that calprotectin, C-reactive protein (CRP), IL-6 and procalcitonin (PCT), alone or in combination, provide clinically useful information to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1d50a1cb9f1730e00dd11b1e02a497
https://doi.org/10.1097/shk.0000000000001981
https://doi.org/10.1097/shk.0000000000001981
Autor:
Kristian Tonby, Ida Wergeland, Nora V. Lieske, Dag Kvale, Kjetil Tasken, Anne M. Dyrhol-Riise
Publikováno v:
BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-12 (2016)
Abstract Background Tuberculosis (TB) causes a major burden on global health with long and cumbersome TB treatment regimens. Host-directed immune modulating therapies have been suggested as adjunctive treatment to TB antibiotics. Upregulated cyclooxy
Externí odkaz:
https://doaj.org/article/94dc22755203432c8ee222b06f4ec129
Autor:
Christian Prebensen, Marius Trøseid, Thor Ueland, Anders Dahm, Per Morten Sandset, Ingeborg Aaberge, Kristian Waalen, Anne Ma Dyrhol-Riise, Kjetil Taskén, Dag Kvale
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176527 (2017)
Pathologically elevated immune activation and inflammation contribute to HIV disease progression and immunodeficiency, potentially mediated by elevated levels of prostaglandin E2, which suppress HIV-specific T cell responses. We have previously shown
Externí odkaz:
https://doaj.org/article/2df4759ccd9e4de9a640c0f75ea825df