Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dafydd Alwyn Dart"'
Publikováno v:
Biology, Vol 13, Iss 9, p 734 (2024)
Prostate cancer is the second most common neoplasia and fifth-leading cause of cancer death in men worldwide. Electromagnetic and magnetic fields have been classified as possible human carcinogens, but current understanding of molecular and cellular
Externí odkaz:
https://doaj.org/article/5f45cc6c40a2408ca823751d2b8dda6b
Autor:
Ben Lanning, Jason Webber, Pinar Uysal-Onganer, Wen Guo Jiang, Aled Clayton, Dafydd Alwyn Dart
Publikováno v:
Biology, Vol 10, Iss 4, p 318 (2021)
Skeletal metastases are the most common form of secondary tumour associated with prostate cancer (PCa). The aberrant function of bone cells neighbouring these tumours leads to the devel-opment of osteoblastic lesions. Communication between PCa cells
Externí odkaz:
https://doaj.org/article/7a393119a4c74e8e9d70c6cf1cc1954c
Autor:
Wen Guo Jiang, Aled Clayton, Ben.E Lanning, Jason P. Webber, Pinar Uysal-Onganer, Dafydd Alwyn Dart
Publikováno v:
Biology
Volume 10
Issue 4
Biology, Vol 10, Iss 318, p 318 (2021)
Volume 10
Issue 4
Biology, Vol 10, Iss 318, p 318 (2021)
Simple Summary Prostate cancer frequently metastasizes to the bone, where it forms primarily osteoblastic lesions. Currently there is no real therapeutic option for this late stage of disease, and understanding prostate cancer-bone interaction and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5aab7cc7f5948716772ccc5168901d2
http://europepmc.org/articles/PMC8069461
http://europepmc.org/articles/PMC8069461
Publikováno v:
Genes, Vol 10, Iss 11, p 921 (2019)
Genes
Volume 10
Issue 11
Genes
Volume 10
Issue 11
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer, proving difficult to manage clinically. Wnt-11, a developmentally regulated gene producing a secreted protein, has been associated with various carcinomas but has not pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45b3cbebaf05cd9331d19d40dfbc902
http://hdl.handle.net/10044/1/75139
http://hdl.handle.net/10044/1/75139
Publikováno v:
Anticancer research. 37(7)
Aim: To examine the expression and function of activin receptor-like kinase 7 (ALK7) in breast cancer, its association with disease prognosis, and its impact on breast cancer cell function. Patients and Methods: A cohort of patients with breast cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6136b136757a22cce7beff852488e1eb
https://pubmed.ncbi.nlm.nih.gov/28668833
https://pubmed.ncbi.nlm.nih.gov/28668833
Autor:
Wen Guo Jiang, Xiaofang Xing, Xiaojing Cheng, Hong Du, Meng Xie, Jiafu Ji, Ting Guo, Dafydd Alwyn Dart, Xian-Zi Wen
Publikováno v:
Gastric Cancer
Background We recently reported that miR-1 was one of the most significantly downregulated microRNAs in gastric cancer (GC) patients from The Cancer Genome Atlas microRNA sequencing data. Here we aim to elucidate the role of miR-1 in gastric carcinog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5791e1f74639c0ef11b8d01847163ef0
https://pubmed.ncbi.nlm.nih.gov/28493075
https://pubmed.ncbi.nlm.nih.gov/28493075
Publikováno v:
R429
R409
R409
Hormones are key drivers of cancer development. To date, interest has largely been focussed on the classical model of hormonal gene regulation, but there is increasing evidence for a role of hormone signalling pathways in post-translational regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea0921a4e9f92057d77cc6d5cf33e93
https://doi.org/10.1530/erc-14-0208
https://doi.org/10.1530/erc-14-0208
Autor:
Dafydd Alwyn Dart, Charlotte L. Bevan
Publikováno v:
Methods in Molecular Biology ISBN: 9781493937226
Nuclear receptors drive key processes during development, reproduction, metabolism, and disease. In order to understand and analyze, as well as manipulate, their actions it is imperative that we are able to study them in whole animals and in a spatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::536b6c43ca9e5d20df55aba7cec2fe81
https://doi.org/10.1007/978-1-4939-3724-0_13
https://doi.org/10.1007/978-1-4939-3724-0_13
Publikováno v:
Oncology reports. 36(3)
Gastric cancer (GC) remains the third most common cause of cancer deaths worldwide and carries a high rate of metastatic risk contributing to the main cause of treatment failure. An accumulation of data has resulted in a better understanding of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d03e74038262e3ca088e36a13a57fda
https://pubmed.ncbi.nlm.nih.gov/27349337
https://pubmed.ncbi.nlm.nih.gov/27349337
Abstract 5468: Neratinib significantly inhibits responses to androgen in human prostate cancer cells
Autor:
Dafydd Alwyn Dart, Wen Guo Jiang, Alshad S. Lalani, Francesca Avogadri-Connors, Richard P. Bryce
Publikováno v:
Cancer Research. 78:5468-5468
Background: Prostate cancer (PCa) is the most commonly diagnosed male cancer in the Western world. Tumor growth is initially androgen dependent - and driven by the androgen receptor (AR). The mainstays of prostate cancer treatment are androgen ablati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b9758d032d7d5b27963c2518c89873b
https://doi.org/10.1158/1538-7445.am2018-5468
https://doi.org/10.1158/1538-7445.am2018-5468