Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dafne Franz"'
Autor:
Ornella Chovar-Vera, Ernesto López, Felipe Gálvez-Cancino, Carolina Prado, Dafne Franz, Diego A. Figueroa, Alexandra Espinoza, Claudio Figueroa, Alvaro Lladser, Rodrigo Pacheco
Publikováno v:
Cells, Vol 11, Iss 22, p 3536 (2022)
Dopamine has emerged as an important regulator of immunity. Recent evidence has shown that signalling through low-affinity dopamine receptors exerts anti-inflammatory effects, whilst stimulation of high-affinity dopamine receptors potentiates immunit
Externí odkaz:
https://doaj.org/article/25e7f9794cd24e7f9aa49c2bbc457a7e
Autor:
James Monypenny, Hanna Milewicz, Fabian Flores-Borja, Gregory Weitsman, Anthony Cheung, Ruhe Chowdhury, Thomas Burgoyne, Appitha Arulappu, Katherine Lawler, Paul R. Barber, Jose M. Vicencio, Melanie Keppler, Wahyu Wulaningsih, Sean M. Davidson, Franca Fraternali, Natalie Woodman, Mark Turmaine, Cheryl Gillett, Dafne Franz, Sergio A. Quezada, Clare E. Futter, Alex Von Kriegsheim, Walter Kolch, Borivoj Vojnovic, Jeremy G. Carlton, Tony Ng
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 630-641 (2018)
Summary: The immunosuppressive transmembrane protein PD-L1 was shown to traffic via the multivesicular body (MVB) and to be released on exosomes. A high-content siRNA screen identified the endosomal sorting complexes required for transport (ESCRT)-as
Externí odkaz:
https://doaj.org/article/271d76a1d4d644ff8f8a80c533ecdc3e
Akademický článek
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Autor:
Johannes Sam, Dafne Franz Demane, Estelle Marrer-Berger, Mariana Werner Sunderland, Christophe Boetsch, Dimitrios Zervas, Anne Goubier, Jake Y. Henry, Teresa Marafioti, Chen Qing, Jan Eckmann, Frederick Arce Vargas, Reto Flury, Sara Belli, Hans Koll, Ayse Akarca, Maria Amann, Bjoern Jacobsen, Lea Leibrock, Anna Śledzińska, Roger Sutmuller, Sergio A. Quezada, Josephine Salimu, Joerg Benz, Claudio Murgia, Isabelle Solomon, Joanne Ruth Clancy, Mark Adrian Brown, Karl S. Peggs, Pascal Merchiers, Ehsan Ghorani, Andrew Georgiou
Publikováno v:
Nature Cancer. 1:1153-1166
Intratumoral regulatory T (Treg) cell abundance associates with diminished antitumor immunity and poor prognosis in human cancers. Recent work demonstrates that CD25, the high-affinity receptor subunit for interleukin (IL)-2, is a selective target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c86e7b1e8eb4c4edbef7ab01a2f5de0
https://doi.org/10.1038/s43018-020-00133-0
https://doi.org/10.1038/s43018-020-00133-0
Autor:
Ido Yofe, Tomer Landsberger, Adam Yalin, Isabelle Solomon, Cristobal Costoya, Dafne Franz Demane, Mansi Shah, Eyal David, Chamutal Borenstein, Oren Barboy, Ignacio Matos, Karl S. Peggs, Sergio A. Quezada, Ido Amit
Publikováno v:
Nature cancer. 3(11)
Despite the clinical success of checkpoint inhibitors, a substantial gap still exists in our understanding of their mechanism of action. While antibodies to cytotoxic T lymphocyte-associated protein-4 (CTLA-4) were developed to block inhibitory signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c893254befca96e58ba21395fcb75fb
https://pubmed.ncbi.nlm.nih.gov/36376510
https://pubmed.ncbi.nlm.nih.gov/36376510
Autor:
Ido Yofe, Tomer Landsberger, Adam Yalin, Isabelle Solomon, Cristobal Costoya, Dafne Franz Demane, Mansi Shah, Eyal David, Chamutal Borenstein, Oren Barboy, Ignacio Matos, Karl S. Peggs, Sergio A. Quezada, Ido Amit
Publikováno v:
Nature Cancer. 3:1404-1404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9d2df2749d109942105d7ba7bcc5c8
https://doi.org/10.1038/s43018-022-00487-7
https://doi.org/10.1038/s43018-022-00487-7
Autor:
Isabelle, Solomon, Maria, Amann, Anne, Goubier, Frederick, Arce Vargas, Dimitrios, Zervas, Chen, Qing, Jake Y, Henry, Ehsan, Ghorani, Ayse U, Akarca, Teresa, Marafioti, Anna, Śledzińska, Mariana, Werner Sunderland, Dafne, Franz Demane, Joanne Ruth, Clancy, Andrew, Georgiou, Josephine, Salimu, Pascal, Merchiers, Mark Adrian, Brown, Reto, Flury, Jan, Eckmann, Claudio, Murgia, Johannes, Sam, Bjoern, Jacobsen, Estelle, Marrer-Berger, Christophe, Boetsch, Sara, Belli, Lea, Leibrock, Joerg, Benz, Hans, Koll, Roger, Sutmuller, Karl S, Peggs, Sergio A, Quezada
Publikováno v:
Nature cancer. 1(12)
Intratumoral regulatory T cell (Treg) abundance associates with diminished anti-tumor immunity and poor prognosis in human cancers. Recent work demonstrates that CD25, the high affinity receptor subunit for IL-2, is a selective target for Treg deplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e9ea9c92fedf39f7b34d066c9a8585a
https://pubmed.ncbi.nlm.nih.gov/35121936
https://pubmed.ncbi.nlm.nih.gov/35121936
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Dafne Franz, Hugo González, Rodrigo Pacheco, Valentina Ugalde, Daniela Elgueta, Francisco Contreras, Carolina Prado, Alvaro Lladser, Alicia Figueroa, Francisco Osorio-Barrios, Ernesto Lopez, Fabiola Osorio
Publikováno v:
The Journal of Immunology. 196:4143-4149
Dopamine receptor D3 (DRD3) expressed on CD4+ T cells is required to promote neuroinflammation in a murine model of Parkinson’s disease. However, how DRD3 signaling affects T cell–mediated immunity remains unknown. In this study, we report that T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd3f7d7ae9e12ea8b0be34e6b11b00e
https://doi.org/10.4049/jimmunol.1502420
https://doi.org/10.4049/jimmunol.1502420
Autor:
Frederick, Arce Vargas, Andrew J S, Furness, Isabelle, Solomon, Kroopa, Joshi, Leila, Mekkaoui, Marta H, Lesko, Enrique, Miranda Rota, Rony, Dahan, Andrew, Georgiou, Anna, Sledzinska, Assma, Ben Aissa, Dafne, Franz, Mariana, Werner Sunderland, Yien Ning Sophia, Wong, Jake Y, Henry, Tim, O'Brien, David, Nicol, Ben, Challacombe, Stephen A, Beers, Samra, Turajlic, Martin, Gore, James, Larkin, Charles, Swanton, Kerry A, Chester, Martin, Pule, Jeffrey V, Ravetch, Teresa, Marafioti, Karl S, Peggs, Julius, Asante-Siaw
Publikováno v:
Immunity
Summary CD25 is expressed at high levels on regulatory T (Treg) cells and was initially proposed as a target for cancer immunotherapy. However, anti-CD25 antibodies have displayed limited activity against established tumors. We demonstrated that CD25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::50ef4aaee0e030ecc9dea48b5e926cbf
https://eprints.soton.ac.uk/414181/
https://eprints.soton.ac.uk/414181/
