Zobrazeno 1 - 10
of 1 252
pro vyhledávání: '"Dafna D, Gladman"'
Autor:
Joseph F Merola, Philip J Mease, Dafna D Gladman, M Elaine Husni, Nadine Goldammer, Jason Coarse, William Tillett, Vanessa Taieb, Jeremy Lambert, Barbara Ink
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Objectives To assess impact of bimekizumab treatment on patient-reported outcomes and health-related quality of life (HRQoL) in patients with active psoriatic arthritis (PsA), using 16-week data from two phase 3 studies.Methods BE OPTIMAL (NCT0389520
Externí odkaz:
https://doaj.org/article/6b47e439da8445b083e973aca1ddd188
Autor:
Lars Erik Kristensen, Atul Deodhar, Ying-Ying Leung, Ivana Vranic, Mahta Mortezavi, Lara Fallon, Arne Yndestad, Cassandra D. Kinch, Dafna D. Gladman
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 3, Pp 487-499 (2024)
Abstract In this commentary, we review clinical data which helps inform individualized benefit–risk assessment for tofacitinib in patients with psoriatic arthritis (PsA) and ankylosing spondylitis (AS). ORAL Surveillance, a safety trial of patients
Externí odkaz:
https://doaj.org/article/0dfdf61802f742879087a07fe9f0706d
Autor:
Vinod Chandran, Louis Bessette, Carter Thorne, Maqbool Sheriff, Proton Rahman, Dafna D. Gladman, Sabeen Anwar, Jennifer Jelley, Anne-Julie Gaudreau, Manprit Chohan, John S. Sampalis
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 2, Pp 443-455 (2024)
Abstract Introduction The APPRAISE study was conducted to better understand the 12-month effectiveness, tolerability, and patient satisfaction with apremilast treatment for patients with psoriatic arthritis (PsA) in real-world settings. Methods APPRA
Externí odkaz:
https://doaj.org/article/e0c68fb386474728b01333870b8c7130
Autor:
Jeffrey R. Curtis, Iain B. McInnes, Proton Rahman, Dafna D. Gladman, Steven Peterson, Feifei Yang, Oluwakayode Adejoro, Alexa P. Kollmeier, Natalie J. Shiff, Chenglong Han, May Shawi, William Tillett, Philip J. Mease
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 2, Pp 425-441 (2024)
Abstract Introduction To evaluate the effect of guselkumab on work productivity and nonwork daily activity impairment and general health status through 2 years in patients who were biologic-naïve with active psoriatic arthritis (PsA) in the phase 3
Externí odkaz:
https://doaj.org/article/0fe4fa79267340eca6264c7603694203
Autor:
Dafna D Gladman, Murray Urowitz, Zahi Touma, Joan Wither, Laura Patricia Whittall-Garcia, Farnoosh Naderinabi, Ana Konvalinka
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Objective To determine if the serum levels of neutrophil extracellular trap (NET) remnants (Elastase-DNA and HMGB1-DNA complexes) at the time of a lupus nephritis (LN) flare predict renal outcomes in the following 24 months.Methods This was a retrosp
Externí odkaz:
https://doaj.org/article/31164ad9369b41fdb314882859b6d20d
Autor:
Joan T Merrill, Ronald F van Vollenhoven, Daniel J Wallace, Susan Manzi, Cynthia Aranow, Anca Askenase, Michelle A Petri, Jill Buyon, Rosalind Ramsey-Goldman, Ian N Bruce, Guillermo Ruiz-Irastorza, Ellen M Ginzler, Graciela S Alarcón, John G Hanly, Murray B Urowitz, Juanita Romero-Diaz, Caroline Gordon, Sang-Cheol Bae, Anisur Rahman, Mary Anne Dooley, Paul R Fortin, Dafna D Gladman, Meggan Mackay, Andreas Jönsen, Sam Lim, Murat Inanc, Diane L Kamen, Christine A Peschken, Søren Jacobsen, Jorge Sanchez-Guerrero, David Isenberg, Marvin J Fritzler, Ann E Clarke, Sasha Bernatsky, Kenneth C Kalunian, Eugene Krustev, May Y Choi, Katherine A Buhler, Ricky Chin
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Background Cranial neuropathies (CN) are a rare neuropsychiatric SLE (NPSLE) manifestation. Previous studies reported that antibodies to the kinesin family member 20B (KIF20B) (anti-KIF20B) protein were associated with idiopathic ataxia and CN. We as
Externí odkaz:
https://doaj.org/article/9208cd215f174ca8b2697b5bb89d40f3
Autor:
Philip J. Mease, Dafna D. Gladman, Denis Poddubnyy, Soumya D. Chakravarty, May Shawi, Alexa P. Kollmeier, Xie L. Xu, Stephen Xu, Atul Deodhar, Xenofon Baraliakos
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 6, Pp 1637-1653 (2023)
Abstract Introduction Guselkumab previously showed greater improvements versus placebo in axial symptoms in patients with psoriatic arthritis (PsA) (assessed by Bath Ankylosing Spondylitis Disease Activity Index [BASDAI] and Ankylosing Spondylitis Di
Externí odkaz:
https://doaj.org/article/78e3cd32eadf45c68aebb23a5cc1f2fa
Autor:
Robert Landewé, Joseph F Merola, Laure Gossec, Frank Behrens, Ana-Maria Orbai, Philip J Mease, Iain B McInnes, Dafna D Gladman, Laura C Coates, Alice B Gottlieb, Vishvesh Shende, Jason Coarse, Christopher T Ritchlin, Richard B Warren, Akihiko Asahina, Barbara Ink, Rajan Bajracharya
Publikováno v:
RMD Open, Vol 10, Iss 1 (2024)
Objectives To assess 52-week safety and efficacy of bimekizumab in patients with active psoriatic arthritis (PsA) and prior inadequate response/intolerance to tumour necrosis factor inhibitors.Methods Patients completing the 16-week phase III double-
Externí odkaz:
https://doaj.org/article/8c6f7873019c4474b1623173fd071db0
Autor:
Laure Gossec, Ana-Maria Orbai, Maarten de Wit, Dafna D Gladman, Laura C Coates, Alexis Ogdie, Vanessa Taieb, Jeremy Lambert, Barbara Ink, Christopher G Pelligra, Valérie Ciaravino
Publikováno v:
RMD Open, Vol 10, Iss 1 (2024)
Objectives To investigate psychometric performance of the 12-item Psoriatic Arthritis Impact of Disease (PsAID-12) total and individual item scores in patients with psoriatic arthritis (PsA) and to estimate score change thresholds and scores correspo
Externí odkaz:
https://doaj.org/article/aa2336a6b90d4afeb287bfb5c55eaac9
Autor:
Carolina Muñoz-Grajales, Michelle L. Barraclough, Juan P. Diaz-Martinez, Jiandong Su, Kathleen Bingham, Mahta Kakvan, Roberta Pozzi Kretzmann, Maria Carmela Tartaglia, Lesley Ruttan, May Y. Choi, Simone Appenzeller, Sherief Marzouk, Dennisse Bonilla, Patricia Katz, Dorcas Beaton, Robin Green, Dafna D. Gladman, Joan Wither, Zahi Touma
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
ObjectiveCognitive impairment (CI) is one of the most common manifestations of Neuropsychiatric Systemic Lupus Erythematosus (NPSLE). Despite its frequency, we have a limited understanding of the underlying immune mechanisms, resulting in a lack of p
Externí odkaz:
https://doaj.org/article/b1f2c06105f248018500a9273e93cd0e