Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dafen Xu"'
Autor:
Bing Chen, Dafen Xu, Zhijun Li, Yafei Jing, Luping Lin, Shaoguang Li, Liying Huang, Xiuwang Huang, Ailin Liu, Xinhua Lin, Hong Yao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/1a9f7212368a438d85d60677d10d0428
Autor:
Bing Chen, Hongbin Luo, Weiying Chen, Qishu Huang, Kaifan Zheng, Dafen Xu, Shaoguang Li, Ailin Liu, Liying Huang, Yanjie Zheng, Xinhua Lin, Hong Yao
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Delicaflavone (DF), a natural active ingredient from Selaginella doederleinii Hieron, has been reported to have favorable anticancer effects and is thus considered a potential anticancer agent. However, its pharmacokinetics and plasma protein binding
Externí odkaz:
https://doaj.org/article/5284f8860df641daaa96a14b61050e52
Autor:
Bing Chen, Xuewen Wang, Yanyan Zhang, Kangping Huang, Hao Liu, Dafen Xu, Shaoguang Li, Qicai Liu, Jianyong Huang, Hong Yao, Xinhua Lin
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 309-322 (2020)
Amentoflavone, robustaflavone, 2″,3″-dihydro-3′,3‴-biapigenin, 3′,3‴-binaringenin, and delicaflavone are five major hydrophobic components in the total biflavonoids extract from Selaginella doederleinii (TBESD) that display favorable anti
Externí odkaz:
https://doaj.org/article/5b2cc319534d4ceabe68ffc9c67d3eb8
Autor:
Shaoguang Li, Xuewen Wang, Gang Wang, Peiying Shi, Shilan Lin, Dafen Xu, Bing Chen, Ailin Liu, Liying Huang, Xinhua Lin, Hong Yao
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Colorectal cancer is one type of cancer with high incidence rate and high mortality worldwide. Thus, developing new chemotherapeutic drugs is important. The Selaginella doederleinii Hieron ethyl acetate (SDEA) extract showed good anti-colon cancer ef
Externí odkaz:
https://doaj.org/article/f810b8c5f87647169805a4670144dc72
Autor:
Xuewen Wang, Dafen Xu, Bing Chen, Dandan Huang, Zhijun Li, Yuxia Sui, Fei Lin, Hong Yao, Huang Yuan Li, Xinhua Lin
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-16
Our previous studies have shown that delicaflavone (DLL), a biocomponent extracted from Selaginella doederleinii Hieron, has antitumor activity. However, the role of DLL in the antitumor immune response is unknown. In this study, we tested the potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c122a9966800f2ea9207f7cae0ab3dc
https://doi.org/10.1155/2022/8619275
https://doi.org/10.1155/2022/8619275
Autor:
Dandan Huang, Dafen Xu, Wenxin Chen, Ruimei Wu, Yujuan Wen, Ailin Liu, Liqing Lin, Xinhua Lin, Xuewen Wang
Background: Hepatocellular carcinoma (HCC) seriously threatens human health and life due to its high mortality. Ferroptosis is an emerging therapeutic based on accumulating the abnormal reactive oxygen species (ROS) of cancer cells. However, the ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd059c0e9d3126994f5237bcb2464805
https://doi.org/10.21203/rs.3.rs-2358203/v1
https://doi.org/10.21203/rs.3.rs-2358203/v1
Publikováno v:
Journal of Ethnopharmacology. 311:116441
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf90f0273b3b37493f0b2947e83ded0a
https://doi.org/10.1016/j.jep.2023.116441
https://doi.org/10.1016/j.jep.2023.116441
Publikováno v:
Journal of ethnopharmacology. 286
Ethnopharmacological relevance Previously, the total bioflavonoids extract from Selaginella doederleinii (SDTBE) presented favorable in vitro and in vivo activities against non-small cell lung cancer (NSCLC), hinting at its medicinal potential. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5037417c3cb0c4b7bae0b986c4e760
https://pubmed.ncbi.nlm.nih.gov/34793885
https://pubmed.ncbi.nlm.nih.gov/34793885
Autor:
Hong Yao, Dafen Xu, Xinhua Lin, Shaoguang Li, Bing Chen, Shaohuang Weng, Yanjie Zheng, Zhen Lin, Jianyong Huang, Xuewen Wang, Dan Lin
Publikováno v:
International Journal of Nanomedicine. 14:6691-6706
Purpose Amentoflavone, robustaflavone, 2'',3''-dihydro-3',3'''-biapigenin, 3',3'''-binaringenin and delicaflavone are five major active ingredients in the total biflavonoids extract from Selaginella doederleinii (TBESD) with favorable anticancer prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff98a74d78cc92b2548c43a18d7f59d
https://doi.org/10.2147/ijn.s214686
https://doi.org/10.2147/ijn.s214686
Autor:
Xuewen Wang, Hao Liu, Bing Chen, Kangping Huang, Hong Yao, Zhengjun Huang, Dafen Xu, Xinhua Lin, Zhijun Li
Publikováno v:
British journal of pharmacologyREFERENCES. 178(6)
Here, we review the molecular mechanism and pharmacokinetics of flavonoids in the treatment of resistant EGF receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) and particularly the possible mechanism(s) of delicaflavone, a biflavonoid extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318852ff35bca00577a6e04c3d3401e6
https://pubmed.ncbi.nlm.nih.gov/33450055
https://pubmed.ncbi.nlm.nih.gov/33450055