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pro vyhledávání: '"Daeun Noh"'
Publikováno v:
ACS Chem Biol
The neuropancreatic polypeptide hormone amylin forms pancreatic islet amyloid in type-2 diabetes. Islet amyloid formation contributes to β-cell death in the disease and to the failure of islet transplants, but the features which influence amylin amy
Autor:
Aisha Ben-Younis, Konstantinos Thalassinos, Charles Eldrid, Daniel P. Raleigh, Zachary Ridgway, Daeun Noh, Alexander Zhyvoloup
Publikováno v:
Biochemistry, vol 59, iss 6
Biochemistry
Biochemistry
Pancreatic amyloid formation by the polypeptide IAPP contributes to β-cell dysfunction in type 2 diabetes. There is a 1:1 correspondence between the ability of IAPP from different species to form amyloid in vitro and the susceptibility of the organi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02caeff4ff79413fdb6db8147d32f41d
https://escholarship.org/uc/item/5sn1r2z0
https://escholarship.org/uc/item/5sn1r2z0
Publikováno v:
Biochemistry
Biochemistry, vol 59, iss 4
Biochemistry, vol 59, iss 4
Amyloid formation by amylin contributes to β-cell dysfunction in type 2 diabetes. The features that control the amyloidogenicity and toxicity of amylin are not understood. Not all species form islet amyloid, and its presence or absence correlates wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8a896231eccf7b0e1ec70f67ef6140
https://europepmc.org/articles/PMC8254015/
https://europepmc.org/articles/PMC8254015/