Zobrazeno 1 - 10
of 431
pro vyhledávání: '"Daehee, Hwang"'
Autor:
Seunghan Han, Bomin Kim, Do Young Hyeon, Daeun Jeong, Jaechan Ryu, Jae-Sung Nam, Yoon Ha Choi, Bo-Ram Kim, Sang Chul Park, Youn Wook Chung, Sung Jae Shin, June-Yong Lee, Jong Kyoung Kim, Jihye Park, Sei Won Lee, Tae-Bum Kim, Jae Hee Cheon, Hyung-Ju Cho, Chang-Hoon Kim, Joo-Heon Yoon, Daehee Hwang, Ji-Hwan Ryu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The IL-23-Th17 axis is responsible for neutrophilic inflammation in various inflammatory diseases. Here, we discover a potential pathway to inhibit neutrophilic asthma. In our neutrophil-dominant asthma (NDA) model, single-cell RNA-seq analy
Externí odkaz:
https://doaj.org/article/6f69f526b19943f29b7f815e950a2a02
Autor:
Yaechan Song, Heeju Na, Seung Eon Lee, You Min Kim, Jihyun Moon, Tae Wook Nam, Yul Ji, Young Jin, Jae Hyung Park, Seok Chan Cho, Jaehoon Lee, Daehee Hwang, Sang-Jun Ha, Hyun Woo Park, Jae Bum Kim, Han-Woong Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Obesity has emerged as a prominent risk factor for the development of malignant tumors. However, the existing literature on the role of adipocytes in the tumor microenvironment (TME) to elucidate the correlation between obesity and cancer re
Externí odkaz:
https://doaj.org/article/60d4f93da40e407caff336bcf08b78b1
Autor:
Jeongsoo Kim, Tae-Jin Kim, Sehyun Chae, Hyojeong Ha, Yejin Park, Sunghee Park, Chul Joo Yoon, Seon Ah Lim, Hyemin Lee, Jiyoung Kim, Jungwon Kim, Kyungtaek Im, Kyunghye Lee, Jeongmin Kim, Daham Kim, Eunju Lee, Min Hwa Shin, Serk In Park, Inmoo Rhee, Keehoon Jung, Jeewon Lee, Keun Hwa Lee, Daehee Hwang, Kyung-Mi Lee
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background In the myeloid compartment of the tumor microenvironment, CD244 signaling has been implicated in immunosuppressive phenotype of monocytes. However, the precise molecular mechanism and contribution of CD244 to tumor immunity in mon
Externí odkaz:
https://doaj.org/article/b9d69d09111a49bdb32d80e3ebb65c32
Autor:
Somin Lee, Hyunkyung Kim, Bum Suk Kim, Sehyun Chae, Sangmin Jung, Jung Seub Lee, James Yu, Kyungmin Son, Minhwan Chung, Jong Kyoung Kim, Daehee Hwang, Sung Hee Baek, Noo Li Jeon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Several functions of autophagy associated with proliferation, differentiation, and migration of endothelial cells have been reported. Due to lack of models recapitulating angiogenic sprouting, functional heterogeneity of autophagy in endothe
Externí odkaz:
https://doaj.org/article/aa9f3fd8ad304ab0a6941c90ed022c38
Autor:
Yaechan Song, Heeju Na, Seung Eon Lee, You Min Kim, Jihyun Moon, Tae Wook Nam, Yul Ji, Young Jin, Jae Hyung Park, Seok Chan Cho, Jaehoon Lee, Daehee Hwang, Sang-Jun Ha, Hyun Woo Park, Jae Bum Kim, Han-Woong Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/857dafac0070417eb68e3131fe999e6a
Autor:
Dongyeop Shin, Myung-Jin Kim, Soyeon Chun, Dongchan Kim, Chansu Lee, Kwang-Sung Ahn, Eunyoung Jung, Dayeon Kim, Byung-Chul Lee, Daehee Hwang, Yonghwan Kim, Sung-Soo Yoon
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Osteolytic bone lesion is a major cause of decreased quality of life and poor prognosis in patients with multiple myeloma (MM), but molecular pathogenesis of the osteolytic process in MM remains elusive. Fms-like tyrosine kinase 3 ligand (FLT3L) was
Externí odkaz:
https://doaj.org/article/3e15b6fb3f6c49e08fa02a7501ffeee9
Autor:
Seungbo Yoo, Yun Hee Jeong, Hong-Hee Choi, Sehyun Chae, Daehee Hwang, Sung Jae Shin, Sang-Jun Ha
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 999-1012 (2023)
Abstract Chronic viral infection impairs systemic immunity in the host; however, the mechanism underlying the dysfunction of immune cells in chronic viral infection is incompletely understood. In this study, we studied the lineage differentiation of
Externí odkaz:
https://doaj.org/article/2d70b49057364b869f851817bfc7cd93
Autor:
Seungchul Lee, Jaemyung Choi, Jihwan Park, Chang Pyo Hong, Daeseok Choi, Soeun Han, Kyuha Choi, Tae-Young Roh, Daehee Hwang, Ildoo Hwang
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-30 (2023)
Abstract Background Plants memorize previous pathogen attacks and are “primed” to produce a faster and stronger defense response, which is critical for defense against pathogens. In plants, cytosines in transposons and gene bodies are reported to
Externí odkaz:
https://doaj.org/article/2ffcc6124a1f4b11aa80d6fc2889dcf3
Autor:
Duk Ki Kim, Juhee Jeong, Dong Sun Lee, Do Young Hyeon, Geon Woo Park, Suwan Jeon, Kyung Bun Lee, Jin-Young Jang, Daehee Hwang, Ho Min Kim, Keehoon Jung
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
A desmoplastic stroma, enriched in cancer-associated fibroblasts (CAF), has been associated with resistance to therapy in patients with pancreatic ductal adenocarcinoma (PDAC). Here, after showing that chemotherapy promotes tumor fibrosis by increasi
Externí odkaz:
https://doaj.org/article/5e2b1e579f974795af201af7c8826ca2
Autor:
Eun Jae Yang, Ji Hwan Park, Hyun-Ji Cho, Jeong-A Hwang, Seung-Hwa Woo, Chi Hyun Park, Sung Young Kim, Joon Tae Park, Sang Chul Park, Daehee Hwang, Young-Sam Lee
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Inhibitors to ATM and ROCK kinases increases the proliferation via transcriptional changes in human diploid fibroblasts undergoing replicative senescence in a synergistic manner
Externí odkaz:
https://doaj.org/article/d259d950c47d4d07860606af3f5e4ab3