Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Daehae Song"'
Autor:
Min Ji Ko, Daehae Song, Juhee Kim, Jae Yong Kim, Jaehyun Eom, Byungje Sung, Yong-Gyu Son, Young Min Kim, Sang Hoon Lee, Weon-Kyoo You, Jinwon Jung
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Antibody–drug conjugates (ADCs) are targeted therapeutic agents that treat cancers by selective delivery of highly potent cytotoxic drugs to tumor cells via cancer-specific antibodies. However, their clinical benefit is limited by off-target toxici
Externí odkaz:
https://doaj.org/article/2dbd7df1c4d047828bca0a29a4ffbb29
Autor:
Jung-Won Shin, Sungwon An, Dongin Kim, Hyunjoo Kim, Jinhyung Ahn, Jaehyun Eom, Weon-Kyoo You, Hyesu Yun, Bora Lee, Byungje Sung, Jinwon Jung, Sehyun Kim, Yonggyu Son, Eunsil Sung, Hanbyul Lee, Suyeon Lee, Daehae Song, Youngdon Pak, Jagdeep K. Sandhu, Arsalan S. Haqqani, Danica B. Stanimirovic, Jiseon Yoo, Donghwan Kim, Sungho Maeng, Jeonghun Lee, Sang Hoon Lee
Publikováno v:
Cell reports methods. 2(11)
Effective delivery of therapeutics to the brain is challenging. Molecular shuttles use receptors expressed on brain endothelial cells to deliver therapeutics. Antibodies targeting transferrin receptor (TfR) have been widely developed as molecular shu