Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Dae-Yeul Yu"'
Autor:
Hyunjoo Kim, Muhah Jeong, Do-Hyeong Na, Shin-Hyeon Ryu, Eun Il Jeong, Kwangmin Jung, Jaemin Kang, Ho-June Lee, Taebo Sim, Dae-Yeul Yu, Hee Chul Yu, Baik-Hwan Cho, Yong-Keun Jung
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-11 (2022)
Abstract The RAS–BRAF signaling is a major pathway of cell proliferation and their mutations are frequently found in human cancers. Adenylate kinase 2 (AK2), which modulates balance of adenine nucleotide pool, has been implicated in cell death and
Externí odkaz:
https://doaj.org/article/fb10c0acc0f142279e3ed6c60c4718e7
Publikováno v:
Annals of Geriatric Medicine and Research, Vol 24, Iss 4, Pp 297-304 (2020)
Background Sestrin2 (Sesn2) is involved in the maintenance of metabolic homeostasis and aging via modulation of the 5' AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) pathway. Methods Wild-type and Sesn2 knockout (KO) mice of t
Externí odkaz:
https://doaj.org/article/07b45251ed8e4b5bb8b08789ff54a68a
Autor:
Inseon Bak, Doo-Jin Kim, Hyoung-Chin Kim, Hye-Jun Shin, Eunhye Yu, Kyeong-Won Yoo, Dae-Yeul Yu
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-11 (2020)
Abstract Genome editing has recently emerged as a powerful tool for generating mutant mice. Small deletions of nucleotides in the target genes are frequently found in CRISPR/Cas9 mediated mutant mice. However, there are very few reports analyzing the
Externí odkaz:
https://doaj.org/article/68674f6206884ab3ac1696a4de81d683
Autor:
Dae-Yeul Yu
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-9 (2020)
Abstract The hepatitis B virus (HBV) infects approximately 240 million people worldwide, causing chronic liver disease (CLD) and liver cancer. Although numerous studies have been performed to date, unfortunately there is no conclusive drug or treatme
Externí odkaz:
https://doaj.org/article/ff63defc45fa445eb7abaceeec412b77
Autor:
Lei Xiong, Feng Wu, Qiong Wu, Liangliang Xu, Otto K. Cheung, Wei Kang, Myth T. Mok, Lemuel L. M. Szeto, Cheuk-Yin Lun, Raymond W. Lung, Jinglin Zhang, Ken H. Yu, Sau-Dan Lee, Guangcun Huang, Chiou-Miin Wang, Joseph Liu, Zhuo Yu, Dae-Yeul Yu, Jian-Liang Chou, Wan-Hong Huang, Bo Feng, Yue-Sun Cheung, Paul B. Lai, Patrick Tan, Nathalie Wong, Michael W. Chan, Tim H. Huang, Kevin Y. Yip, Alfred S. Cheng, Ka-Fai To
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
There are distinct hypermethylation patterns in gene promoters in hepatocellular carcinomas (HCCs). Here, the authors show that the enhancer of C/EBPβ is recurrently hypomethylated in human HCCs, recapitulating this in a transgenic murine model and
Externí odkaz:
https://doaj.org/article/3f6c3461a5c841138bb59978799a70b5
Autor:
John T. Olthoff, Angus Lindsay, Reem Abo-Zahrah, Kristen A. Baltgalvis, Xiaobai Patrinostro, Joseph J. Belanto, Dae-Yeul Yu, Benjamin J. Perrin, Daniel J. Garry, George G. Rodney, Dawn A. Lowe, James M. Ervasti
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In the mdx mouse model of Duchenne muscular dystrophy, muscle contractions lead to force loss, which is attributed to myofibre damage. Here, the authors show that force loss is instead mediated by a redox circuit involving NOX2, PROX1, myoglobin and
Externí odkaz:
https://doaj.org/article/223d776794074fb79b1d4e9d6b3d3b4f
Autor:
Dong Hoon Kang, Doo Jae Lee, Sunmi Lee, So-Young Lee, Yukyung Jun, Yerin Kim, Youngeun Kim, Ju-Seog Lee, Dae-Kee Lee, Sanghyuk Lee, Eek-Hoon Jho, Dae-Yeul Yu, Sang Won Kang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
2-Cys peroxiredoxin (Prx) enzymes are highly expressed in most cancers but how they promote cancer progression is unclear. Here the authors show that in colorectal cancers with APC mutation, PrxII binds to tankyrase and prevents its oxidative inactiv
Externí odkaz:
https://doaj.org/article/e27578deda874e92af1b15fb7b61a1bd
Autor:
Sang Kyum Kim, Honsoul Kim, Gou Young Koh, Dae-Sik Lim, Dae-Yeul Yu, Man Deuk Kim, Mi-Suk Park, Joon Seok Lim
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131687 (2015)
Human hepatocellular carcinoma (HCC) has unique vascular features, which require selective imaging of hepatic arterial perfusion and portal venous perfusion with vascular catheterization for sufficient evaluation. Unlike in humans, vessels in mice ar
Externí odkaz:
https://doaj.org/article/3a359384478740c582775443c60700e1
Autor:
Mark A. Feitelson, Dae-Yeul Yu, Anna Mae Diehl, Guanhua Xie, Steve S. Choi, Marcia M. Clayton, Vaishnavi Sambandam, Alla Arzumanyan
PDF file - 2.3MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6063a0e315336afcb7727ee27f6e266c
https://doi.org/10.1158/0008-5472.22395252
https://doi.org/10.1158/0008-5472.22395252
Autor:
Mark A. Feitelson, Dae-Yeul Yu, Anna Mae Diehl, Guanhua Xie, Steve S. Choi, Marcia M. Clayton, Vaishnavi Sambandam, Alla Arzumanyan
PDF file - 69K, Summary of IHC staining for HBx, Shh, Ihh, Gli2 and PTCH1 among HBV infected patients with HCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc26470238bd47a871b1da4dbd43e042
https://doi.org/10.1158/0008-5472.22395243
https://doi.org/10.1158/0008-5472.22395243