Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Dae-Seog Lim"'
Publikováno v:
Journal of Immunology Research, Vol 2024 (2024)
Dendritic cells (DCs) are specialized antigen-presenting cells that are crucial for maintaining self-tolerance, initiating immune responses against pathogens, and patrolling body compartments. Despite promising aspects, DC-based immunotherapy faces c
Externí odkaz:
https://doaj.org/article/934ee944b99f45158edcba8e826a961d
Autor:
Ji-Soo Oh, Sung-Uk Hwang, Kyung-Eun Noh, Jun-Ho Lee, So-Yeon Choi, Ji-Hee Nam, Min-Seon Song, Nam-Chul Jung, Jie-Young Song, Han Geuk Seo, Younghwa Na, Dae-Seog Lim
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 9, Pp 3809-3821 (2022)
The newly synthesized compound TGF-β signaling agonist (T74) is a small molecule associated with the TGF-β receptor signaling pathway. Tolerogenic dendritic cells (tDCs) have been used to examine immunosuppressive and anti-inflammatory effects in m
Externí odkaz:
https://doaj.org/article/4bcc0dc6c6a946c0995802e69def93d3
Autor:
Ji-Hee Nam, Jun-Ho Lee, Hyun-Ji Choi, So-Yeon Choi, Kyung-Eun Noh, Nam-Chul Jung, Jie-Young Song, Jinjung Choi, Han Geuk Seo, Sang Youn Jung, Dae-Seog Lim
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5650 (2022)
Mitophagy is a selective form of autophagy that removes damaged mitochondria. Increasing evidence indicates that dysregulated mitophagy is implicated in numerous autoimmune diseases, but the role of mitophagy in rheumatoid arthritis (RA) has not yet
Externí odkaz:
https://doaj.org/article/1fc19df6cba24e8eb3a574e4802bd8aa
Publikováno v:
Translational Oncology, Vol 11, Iss 3, Pp 686-690 (2018)
As a treatment for solid tumors, dendritic cell (DC)-based immunotherapy has not been as effective as expected. Here, we review the reasons underlying the limitations of DC-based immunotherapy for solid tumors and ask what can be done to improve immu
Externí odkaz:
https://doaj.org/article/22d792e14daf4605999d0f959efffcb4
Autor:
Jun-Ho Lee, So-Yeon Choi, Soo-Yeoun Park, Nam-Chul Jung, Kyung-Eun Noh, Ji-Hee Nam, Ji-Soo Oh, Hyun-Ji Choi, Ji-Su Jang, Ji-Young Yoo, Jie-Young Song, Han Geuk Seo, Dae-Seog Lim
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1727 (2021)
Enpp2 is an enzyme that catalyzes the conversion of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), which exhibits a wide variety of biological functions. Here, we examined the biological effects of Enpp2 on dendritic cells (DCs), which
Externí odkaz:
https://doaj.org/article/513bdf9b0c1c48bb8aa4ec6be5b96d04
Autor:
Kyung-Eun Noh, Jun-Ho Lee, So-Yeon Choi, Nam-Chul Jung, Ji-Hee Nam, Ji-Soo Oh, Jie-Young Song, Han Geuk Seo, Yu Wang, Hyun Soo Lee, Dae-Seog Lim
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8706 (2021)
Chimeric antigen receptor (CAR)-T cells are effective in the treatment of hematologic malignancies but have shown limited efficacy against solid tumors. Here, we demonstrated an approach to inhibit recurrence of B cell lymphoma by co-expressing both
Externí odkaz:
https://doaj.org/article/0e911226de254fbab44a6d43f35d8abf
Autor:
Jung Seok Hwang, Jinwoo Hur, Won Jin Lee, Jun Pil Won, Hyuk Gyoon Lee, Dae-Seog Lim, Eunsu Kim, Han Geuk Seo
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1223 (2021)
Hypertrophy of myocytes has been implicated in cardiac dysfunctions affecting wall stress and patterns of gene expression. However, molecular targets potentially preventing cardiac hypertrophy have not been fully elucidated. In the present study, we
Externí odkaz:
https://doaj.org/article/2dfe6a4700ee46a493be9d682ff41682
Autor:
Eun Sil Kang, Jung Seok Hwang, Won Jin Lee, Gyeong Hee Lee, Mi-Jung Choi, Kyung Shin Paek, Dae-Seog Lim, Han Geuk Seo
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210482 (2019)
We investigated the effect of peroxisome proliferator-activated receptor δ (PPARδ) on angiotensin II (Ang II)-triggered hypertrophy of vascular smooth muscle cells (VSMCs). Activation of PPARδ by GW501516, a specific ligand of PPARδ, significantl
Externí odkaz:
https://doaj.org/article/353cffe9a4184f249c0c4b4631e744b6
Autor:
Ji-Hee Nam, Jun-Ho Lee, So-Yeon Choi, Nam-Chul Jung, Jie-Young Song, Han-Geuk Seo, Dae-Seog Lim
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4430 (2021)
Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs) and inducers of T cell-mediated immunity. Although DCs play a central role in promoting adaptive immune responses against growing tumors, they also establish and m
Externí odkaz:
https://doaj.org/article/6aa3b26f23814b8084330aece815d69b
Autor:
Jung Seok Hwang, Eun Sil Kang, Sung Gu Han, Dae-Seog Lim, Kyung Shin Paek, Chi-Ho Lee, Han Geuk Seo
Publikováno v:
PeerJ, Vol 6, p e4208 (2018)
Background The release of high mobility group box 1 (HMGB1) induced by inflammatory signals acts as a cellular alarmin to trigger a chain of inflammatory responses. Although the inflammatory actions of HMGB1 are well studied, less is known about the
Externí odkaz:
https://doaj.org/article/f663d79f21984620bd5ba2cdc5ca589a