Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dae-Jin Cho"'
Autor:
Suji Baek, Seung Hae Kwon, Joo Yeong Jeon, Gong Yeal Lee, Hyun Soo Ju, Hyo Jung Yun, Dae Jin Cho, Kang Pa Lee, Myung Hee Nam
Publikováno v:
BMC Pharmacology and Toxicology, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Tyrosine kinase (TK) plays a crucial role in the pathogenesis of idiopathic pulmonary fibrosis. Here, we aimed to investigate whether radotinib (Rb) could inhibit pulmonary fibrosis by inhibiting TK in vitro and in vivo. Methods T
Externí odkaz:
https://doaj.org/article/56d195ea472a4b0e88ed014a5c5a29e2
Autor:
Sung-Hyun Kim, Hari Menon, Saengsuree Jootar, Tapan Saikia, Jae-Yong Kwak, Sang-Kyun Sohn, Joon Seong Park, Seong Hyun Jeong, Hyeoung Joon Kim, Yeo-Kyeoung Kim, Suk Joong Oh, Hawk Kim, Dae Young Zang, Joo Seop Chung, Ho Jin Shin, Young Rok Do, Jeong-A Kim, Dae-Young Kim, Chul Won Choi, Sahee Park, Hye Lin Park, Gong Yeal Lee, Dae Jin Cho, Jae Soo Shin, Dong-Wook Kim
Publikováno v:
Haematologica, Vol 99, Iss 7 (2014)
Radotinib (IY5511HCL), a novel and selective BCR-ABL1 tyrosine kinase inhibitor, has shown pre-clinical and phase I activity and safety in chronic myeloid leukemia. This phase II study investigated the efficacy and safety of radotinib in Philadelphia
Externí odkaz:
https://doaj.org/article/45f225b4d63943de86f74f1a0441e958
Autor:
Jeongmin Park, Dong Yeon Kim, Daeho Cho, Dae Jin Cho, Kyung Eun Kim, Hyun Jeong Park, Sunyoung Park, Dae Young Hur, Soyoung Cheon
Publikováno v:
Journal of Immunology Research
Radotinib (Supect™) was developed to treat chronic myeloid leukemia (CML) as a BCR-ABL1 tyrosine kinase inhibitor (TKI). Other TKIs, including imatinib and nilotinib, were also developed for treatment of CML, and recent studies were increasing abou
Autor:
Hyun Soo Ju, Sehee Park, Mee Sook Park, Dong Yeon Kim, Kiwon Ok, Jun Heo, Jae Soo Shin, Hong Youb Kim, Youngjoo Byun, Chung Am Ahn, Hae Un Lee, Hye Jin Bang, Joon Yong Bae, Man Seong Park, Dae Jin Cho, Sangmoo Lee, Jin Il Kim, Seok Hun Woo, Gong Yeal Lee
Publikováno v:
Journal of Virology. 93
Combating influenza is one of the perennial global public health issues to be managed. Antiviral drugs are useful for the treatment of influenza in the absence of an appropriate vaccine. However, the appearance of resistant strains necessitates a con
Autor:
Eun Ah Jung, Wonjoong Richard Kim, Han Seok Ko, Jae Soo Shin, Dong-Hoon Kim, Hyun Soo Ju, Dae Jin Cho, Seung-Hwan Kwon, Jae Hong Park, Seung Pil Yun, Saebom Lee, Gong Yeal Lee, Hyo Jung Yun, Yong Joo Park, Seulki Lee, Sangjune Kim, Dong Yeon Kim
Publikováno v:
Human molecular genetics. 27(13)
Accumulating evidence suggests that the non-receptor tyrosine kinase c-Abl plays an important role in the progression of Parkinson's disease (PD) and c-Abl inhibition could be neuroprotective in PD and related α-synucleinopathies. Nilotinib, a c-Abl
Publikováno v:
Atomization and Sprays. 20:639-652
Autor:
Min Soo Park, Dae Young Zang, Hayeon Noh, Hye Lin Park, Sukjoong Oh, Jangik I. Lee, Sung-Hyun Kim, Dong-Wook Kim, Dae Jin Cho
Publikováno v:
Leukemialymphoma. 57(8)
A fixed dose regimen for tyrosine kinase inhibitors (TKIs) is postulated to be responsible for variable safety outcomes in the treatment of chronic myelogenous leukemia (CML). The objective of this study was to explore an optimal dosing regimen for a
Autor:
Young Hoon Jung, Won Hun Ham, Sun Yong Jin, Dae Jin Cho, Nam-Tae Woo, Jee-Hyung Jung, Eun Hyung Bae, Nam Sun Kim
Publikováno v:
Archives of Pharmacal Research. 20:176-179
Purine nucleosides were chlorinated by the reaction of acyl chloride in DMF with MCPBA under mild conditions with moderate yields. And, satisfactory method for the synthesis of ribonucleoside-3',5'-cyclic phosphates and its characterization by(1)H an
Autor:
Nam-Tae Woo, Sun Yong Jin, Ducky Han, Nam Sun Kim, Byung Hoon Han, Young-Hwa Kang, Eun Hyung Bae, Dae Jin Cho
Publikováno v:
Archives of Pharmacal Research. 20:80-84
Substituted cinnamoyl-tyramine derivatives were synthesized by DCC-coupling of substituted cinnamic acid with tyramine or tyramine methyl-1-ether to evaluate PAF-receptor binding antagonistic activities and inhibitory activities on PAF-induced platel
Autor:
Saebom Lee, Sangjune Kim, Yong Joo Park, Seung Pil Yun, Seung-Hwan Kwon, Donghoon Kim, Dong Yeon Kim, Jae Soo Shin, Dae Jin Cho, Gong Yeal Lee, Hyun Soo Ju, Hyo Jung Yun, Jae Hong Park, Wonjoong Richard Kim, Eun Ah Jung, Seulki Lee, Han Seok Ko
Publikováno v:
Human Molecular Genetics; 7/1/2018, Vol. 27 Issue 13, p2344-2356, 13p