Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Dae-Hyun Roh"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Neuroactive steroids (NASs) directly affect neuronal excitability. Despite their role in the nervous system is intimately linked to pain control, knowledge is currently limited. This study investigates the peripheral involvement of NASs in c
Externí odkaz:
https://doaj.org/article/fe90905015074b948e50cf878a98bb44
Publikováno v:
Japanese Dental Science Review, Vol 59, Iss , Pp 253-262 (2023)
Metagenomics and metatranscriptomics have enhanced our understanding of the oral microbiome and its impact on oral health. However, these approaches have inherent limitations in exploring individual cells and the heterogeneity within mixed microbial
Externí odkaz:
https://doaj.org/article/4b94a89b6eb744e2814bf499a58e07cb
Autor:
Hyunjin Shin, Jaehyuk Kim, Sheu-Ran Choi, Dong-Wook Kang, Ji-Young Moon, Dae-Hyun Roh, Miok Bae, Jungmo Hwang, Hyun-Woo Kim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract It has been suggested that stress responses induced by fasting have analgesic effects on nociception by elevating the levels of stress-related hormones, while there is limited understanding of pain control mechanisms. Here, we investigated w
Externí odkaz:
https://doaj.org/article/6d6f43d5414d4ae692af9eb9f4778d41
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Progesterone has been shown to have neuroprotective capabilities against a wide range of nervous system injuries, however there are negative clinical studies that have failed to demonstrate positive effects of progesterone therapy. Specifically, we l
Externí odkaz:
https://doaj.org/article/0dcf3c2a87194afea0bf72826b8b8bd0
Publikováno v:
Integrative Medicine Research, Vol 12, Iss 4, Pp 100999- (2023)
Background: Peripheral hypersensitivities develop in the face and hindpaws of mice with nitroglycerin (NTG)-induced migraine. We evaluated whether diluted bee venom (DBV) injections at acupoints prevented these peripheral hypersensitivities and c-Fos
Externí odkaz:
https://doaj.org/article/773fe2d423ce40b79ab66e2a9a134b7f
Autor:
Ji-Hee Yeo, Dae-Hyun Roh
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. We previously demonstrated that the mammalian target of rapamycin (mTOR) inhibitor rapamyc
Externí odkaz:
https://doaj.org/article/afa18130a0a243e1b8be52554a7e6cc5
Publikováno v:
Life, Vol 12, Iss 9, p 1294 (2022)
The pathophysiological mechanism underlying migraine-associated peripheral hypersensitivity remains unclear. Acid-sensing ion channels (ASICs) and transient receptor potential ankyrin 1 (TRPA1) are known to be causative pathogenic factors of mechanic
Externí odkaz:
https://doaj.org/article/4f8347ca958447dcb3008cd6bb7ddd86
Autor:
Ji-Hee Yeo, Dae-Hyun Roh
Publikováno v:
Life, Vol 12, Iss 2, p 215 (2022)
Administration of dexmedetomidine significantly induces sedation and anti-nociception in several nociceptive models, but clinical trials are restricted due to adverse side effects, including lethargy, hypotension, and bradycardia. Herein, we investig
Externí odkaz:
https://doaj.org/article/7ce56cde721c4456bfdbb68156872baf
Publikováno v:
Toxins, Vol 7, Iss 7, Pp 2571-2585 (2015)
The administration of diluted bee venom (DBV) into an acupuncture point has been utilized traditionally in Eastern medicine to treat chronic pain. We demonstrated previously that DBV has a potent anti-nociceptive efficacy in several rodent pain model
Externí odkaz:
https://doaj.org/article/ab2e7a2011704091b752adc317ead8a2
Publikováno v:
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
The mammalian target of rapamycin (mTOR) plays a role in various cellular phenomena, including autophagy, cell proliferation, and differentiation. Although recent studies have reported its involvement in nociceptive responses in several pain models,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa283534b102e715031b40ac3d3b6050
https://doi.org/10.4196/kjpp.2021.25.4.365
https://doi.org/10.4196/kjpp.2021.25.4.365