Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Dae Soo Kim"'
Autor:
Ohman Kwon, Hana Lee, Jaeeun Jung, Ye Seul Son, Sojeong Jeon, Won Dong Yoo, Naeun Son, Kwang Bo Jung, Eunho Choi, In-Chul Lee, Hyung-Jun Kwon, Chuna Kim, Mi-Ok Lee, Hyun-Soo Cho, Dae Soo Kim, Mi-Young Son
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Three-dimensional human intestinal organoids (hIO) are widely used as a platform for biological and biomedical research. However, reproducibility and challenges for large-scale expansion limit their applicability. Here, we establish a human
Externí odkaz:
https://doaj.org/article/6f5d70098bfd4eaabe1920746c0323fc
Publikováno v:
Crystals, Vol 9, Iss 7, p 364 (2019)
Polymer-dispersed liquid crystals (PDLCs) refer to nematic liquid crystals, which are embedded in a polymer matrix. A conventional PDLC device is fabricated by phase separation. However, this method leads to non-uniform electro-optical characteristic
Externí odkaz:
https://doaj.org/article/e6bb2363634c4bca826e62931fd0efe0
Autor:
Anna Park, Kwang-eun Kim, Isaac Park, Sang Heon Lee, Kun-Young Park, Minkyo Jung, Xiaoxu Li, Maroun Bou Sleiman, Su Jeong Lee, Dae-Soo Kim, Jaehoon Kim, Dae-Sik Lim, Eui-Jeon Woo, Eun Woo Lee, Baek Soo Han, Kyoung-Jin Oh, Sang Chul Lee, Johan Auwerx, Ji Young Mun, Hyun-Woo Rhee, Won Kon Kim, Kwang-Hee Bae, Jae Myoung Suh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of generating heat via uncoupled respiration. Mitochondrial uncoupling protein 1 (UCP1) is activated in BAT during cold stress and dissipates mitochondrial proto
Externí odkaz:
https://doaj.org/article/8abfab449c994b11bb6233d6bda9aba7
Autor:
Kwangho Kim, Tae Young Ryu, Eunsun Jung, Tae-Su Han, Jinkwon Lee, Seon-Kyu Kim, Yu Na Roh, Moo-Seung Lee, Cho-Rok Jung, Jung Hwa Lim, Ryuji Hamamoto, Hye Won Lee, Keun Hur, Mi-Young Son, Dae-Soo Kim, Hyun-Soo Cho
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 952-964 (2023)
Abstract Epigenetic alterations, especially histone methylation, are key factors in cell migration and invasion in cancer metastasis. However, in lung cancer metastasis, the mechanism by which histone methylation regulates metastasis has not been ful
Externí odkaz:
https://doaj.org/article/27c0d4a625994a9cb996c9922caa7bad
Autor:
Ye Seul Son, Naeun Son, Won Dong Yu, Aruem Baek, Young-Jun Park, Moo-Seung Lee, Seon-Jin Lee, Dae-Soo Kim, Mi-Young Son
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundA growing body of evidence suggests that particulate matter (PM10) enters the gastrointestinal (GI) tract directly, causing the GI epithelial cells to function less efficiently, leading to inflammation and an imbalance in the gut microbiome
Externí odkaz:
https://doaj.org/article/17bc48fa6c944d408a5e812e721e49ac
Autor:
Hana Lee, Kwang Bo Jung, Ohman Kwon, Ye Seul Son, Eunho Choi, Won Dong Yu, Naeun Son, Jun Hyoung Jeon, Hana Jo, Haneol Yang, Yeong Rak Son, Chan-Seok Yun, Hyun-Soo Cho, Sang Kyu Kim, Dae-Soo Kim, Doo-Sang Park, Mi-Young Son
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Little is known about the modulatory capacity of the microbiota in early intestinal development. We examined various intestinal models that respond to gut microbial metabolites based on human pluripotent stem cell-derived human intestinal organoids (
Externí odkaz:
https://doaj.org/article/bcedc8c3adae41f9bf2188ec7de1d48b
Publikováno v:
Organoid, Vol 2 (2022)
Background Epigenetic regulation of oncogenes and tumor suppressor genes by histone methyltransferases is an important process for colon cancer growth and metastasis. Although various epigenetic modifiers have been recognized as attractive therapeuti
Externí odkaz:
https://doaj.org/article/7559a3032f3e4e43b00983b41db20659
Autor:
Mi-Ok Lee, Su-gi Lee, Cho-Rok Jung, Ye Seul Son, Jae-Woon Ryu, Kwang Bo Jung, Jun-Ho Ahn, Jung-Hwa Oh, Hyang-Ae Lee, Jung Hwa Lim, Janghwan Kim, Insu Jang, Jinhyuk Choi, Jaeeun Jung, Kunhyang Park, Byungwook Lee, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Quantitative methods to assess the quality of hPSC-derived organoids have not been developed. Here they present a prediction algorithm to assess the transcriptomic similarity between hPSC-derived organoids and the corresponding human target organs an
Externí odkaz:
https://doaj.org/article/27708e935ee5482783e2d1c6359a3d60
Autor:
Ilkyu Park, Jaeeun Jung, Sugi Lee, Kunhyang Park, Jea-Woon Ryu, Mi-Young Son, Hyun-Soo Cho, Dae-Soo Kim
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Inflammatory bowel disease (IBD) is a chronic and idiopathic inflammatory disorder of the gastrointestinal tract and comprises ulcerative colitis (UC) and Crohn’s disease (CD). Crohn’s disease can affect any part of the gastro
Externí odkaz:
https://doaj.org/article/4fd50a57e4104765b68d5778ea797f4e
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 2639-2646 (2020)
Papillary renal cell carcinoma (pRCC), which accounts for 10–15% of renal cell carcinomas, is the second most frequent renal cell carcinoma. pRCC patient classification is difficult because of disease heterogeneity, histologic subtypes, and variati
Externí odkaz:
https://doaj.org/article/0d0782ede7d541e6b5a089266e3a4e3c