Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Dae Ryong Cha"'
Autor:
Do Hyoung Kim, Young Youl Hyun, Jin Joo Cha, Sua Lee, Hyun Kyung Lee, Jong Wook Choi, Su-Hyun Kim, Sang Youb Han, Cheol Whee Park, Eun Young Lee, Dae Ryong Cha, Sung Gyun Kim, Chun Soo Lim, Sun-Hee Park
Publikováno v:
Kidney Research and Clinical Practice, Vol 43, Iss 1, Pp 8-19 (2024)
In response to the increase in the prevalence of chronic kidney disease (CKD) in Korea, the growth of patients requiring renal replacement therapy and the subsequent increase in medical costs, the rapid expansion of patients with end-stage kidney dis
Externí odkaz:
https://doaj.org/article/f913355e7d70406f806f1ab02b857d1e
Publikováno v:
Kidney & Blood Pressure Research, Vol 49, Iss 1, Pp 81-90 (2024)
Introduction: Sodium-glucose cotransporter 2 (SGLT2) inhibitors target SGLT2 in renal proximal tubules and promote glycosuria in type 2 diabetes mellitus in humans and animal models, resulting in reduced blood glucose levels. Although clinical trials
Externí odkaz:
https://doaj.org/article/0c74f7d139b74404a08bd234905a2bfc
Autor:
Jin Joo Cha, Boo Yeon Park, Sung Gi Yoon, Hye Jin Park, Ji Ae Yoo, Jung Yeon Ghee, Dae Ryong Cha, Jae Young Seong, Young Sun Kang
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 187-196 (2023)
ABSTRACTThe spexin-based GALR2 agonist (NS200) is a novel drug, which has shown antidepressant and anxiolytic action in a recent experimental study. In this study, we investigated the effects of NS200 on renal injury in an animal model of type 2 diab
Externí odkaz:
https://doaj.org/article/b3688d217e9346e4a944dfc9797c6973
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 112-119 (2023)
ABSTRACTPuromycin treatment can cause glomerular injury to the kidney, leading to proteinuria. However, the pathogenesis of acute kidney injury and subsequent regeneration after puromycin administration in animal models remain unclear. In this work,
Externí odkaz:
https://doaj.org/article/b5214c4f71b1474aa4f132651da2c9c9
Autor:
Sae Rom Lee, Hye Eun Lee, Jung-Yeon Yoo, Eun Jung An, Soo-Jin Song, Ki-Hwan Han, Dae Ryong Cha, Yun Soo Bae
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108868- (2024)
Summary: Nox4-derived H2O2 generation plays an important role in the pathogenesis of chronic kidney diseases (CKDs) such as diabetic nephropathy (DN). Here, we showed that SH3 domain-containing Ysc84-like 1 (SH3YL1), a Nox4 cytosolic activator, regul
Externí odkaz:
https://doaj.org/article/b4a1e488d3bf452e968bb23c2e9e9a5e
Autor:
Jihyun Yang, Bong Gyun Sun, Hyeon-Jin Min, Young-Bin Son, Tae Bum Kim, Jonghyun Lee, Se Won Oh, Myung-Gyu Kim, Won Yong Cho, Shin Young Ahn, Gang-Jee Ko, Young Joo Kwon, Jin Joo Cha, Young Sun Kang, Dae Ryong Cha, Sang-Kyung Jo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Obstructive uropathy is known to be associated with acute kidney injury (AKI). This study aimed to investigate the etiologies, clinical characteristics, consequences and also assess the impact of AKI on long-term outcomes. This multicenter,
Externí odkaz:
https://doaj.org/article/32b1e064bec5459eb71209ed32f53529
Publikováno v:
Kidney Research and Clinical Practice, Vol 41, Iss Suppl 2, Pp S74-S88 (2022)
Diabetic kidney disease (DKD) is now a pandemic worldwide, and novel therapeutic options are urgently required. Adenosine, an adenosine triphosphate metabolite, plays a role in kidney homeostasis through interacting with four types of adenosine recep
Externí odkaz:
https://doaj.org/article/ca8ef4fb91844615a47348b84b6bda45
Autor:
Dae Ryong Cha
Publikováno v:
Kidney Research and Clinical Practice, Vol 41, Iss Suppl 2, Pp S31-S32 (2022)
Externí odkaz:
https://doaj.org/article/750f17ef239b41b4af9d05e7f1cc1ba5
Publikováno v:
Kidney Research and Clinical Practice, Vol 40, Iss 1, Pp 69-76 (2021)
Background Imbalance of T helper (Th) 1/2 cells has been shown to contribute to the development of immunoglobulin A nephropathy (IgAN). To address the inconsistent results on the role of Th1/Th2 polarization, we evaluated the levels of Th1/Th2 cytoki
Externí odkaz:
https://doaj.org/article/919269d6ffd8465aaa3322b069e21e56
Publikováno v:
Life, Vol 13, Iss 4, p 963 (2023)
NADPH oxidase (NOX)-derived oxidative stress is an important factor in renal progression, with NOX4 being the predominant NOX in the kidney. Recently, Src homology 3 (SH3) domain-containing YSC84-like 1 (SH3YL1) was reported to be a regulator of NOX4
Externí odkaz:
https://doaj.org/article/89628234c9c84b79ad1015747bb9a7bc