Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dae Hee Cheon"'
Autor:
Yuri Choi, Ji Su Park, Jinshil Kim, Kyungjin Min, Kiran Mahasenan, Choon Kim, Hye-Jin Yoon, Sewon Lim, Dae Hee Cheon, Yan Lee, Sangryeol Ryu, Shahriar Mobashery, B. Moon Kim, Hyung Ho Lee
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Peptidoglycan hydrolase 3 (Pgp3) inhibitors are designed that can change the helical morphology of Campylobacter jejuni to rod-shaped and decrease its virulence.
Externí odkaz:
https://doaj.org/article/14a44cf5a1054c018de8b0c7a7924892
Autor:
Jaehoon Yu, Yan Lee, Joon Hyung Ahn, Soonsil Hyun, So Hee Nam, Joomyung Jang, Seung-Eun Chong, Dae Hee Cheon
Publikováno v:
Journal of Controlled Release. 330:898-906
We developed a pH-activatable cell-penetrating peptide dimer LH2 with histidine residues, which can penetrate cells, specifically in weak acidic conditions, even at few tens of nanomolar concentrations. LH2 effectively delivered paclitaxel into tripl
Autor:
Wanki Yoo, Doyeon Jo, Dae Hee Cheon, Su-Jin Park, Seo-Yeon Kim, Soonsil Hyun, Tae Woo Park, Yoonhwa Choi, Seolah Choo, Rekha Arya, Yang Soo Kim, Jaehoon Yu, Kyeong Kyu Kim, Sun Mi Jin, So-Hyun Park, Yong Pil Chong, Yan Lee, Seonju Lee
Publikováno v:
Journal of Medicinal Chemistry. 63:14937-14950
Gram-negative bacteria are becoming resistant to almost all currently available antibiotics. Systemically designed antimicrobial peptides (AMPs) are attractive agents to enhance the activities of antibiotics. We constructed a small Pro-scanning libra
Publikováno v:
Chemical communications (Cambridge, England). 57(19)
In an effort designed to discover superior inhibitors of cyclophilin D (CypD), we identified and screened members of a one-bead-one-compound (OBOC) library of cyclic peptoid analogues of cyclosporin A (CsA). The results show that the one member of th
Autor:
Dae Hee Cheon, Yan Lee, Yaejin Yun, Joon Hyung Ahn, Hojoon Song, Jae Hoon Oh, Dahyun Chun, Sohee Nam, Seung-Eun Chong, Sejong Choi, Sunah Kang, So-Hyun Park
Publikováno v:
Biomacromolecules. 21(9)
In this study, we propose a reversible covalent conjugation method for peptides, proteins, and even live cells based on specific recognition between natural amino acid sequences. Two heptad sequences can specifically recognize each other and induce t
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1869:140604
The penetration of biological membranes is a prime obstacle for the delivery of pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver various cargos across the biological membranes. Since the discovery, CPPs ha