Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Dae Ghon Kim"'
Autor:
Jong-Hwan Kim, Mi-Jin Lee, Goung-Ran Yu, Sang-Wook Kim, Kyu-Yun Jang, Hee-Chul Yu, Baik-Hwan Cho, Dae-Ghon Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-10 (2018)
Colon cancer: A delicate balance to regulate growth Insights into a signaling protein’s role in cell growth could inform new therapeutic strategies for treating colon cancer. SOCS-2 acts as an ‘off switch’ for cell signaling pathways. It has be
Externí odkaz:
https://doaj.org/article/c9fe6c02bb1747d18780e0243ee69e40
Autor:
Ju-Seog Lee, Yun-Yong Park, Randy L. Johnson, In-Sun Chu, Minse Cha, Manal M. Hassan, Ahmed Kaseb, Sun-Hee Leem, Dae-Ghon Kim, Yoon Jun Kim, Jeonghoon Heo, Eun Sung Park, Sung Soo Kim, Woojin Jeong, Sang-Cheol Kim, Hyun-Sung Lee, Hee-Jin Jang, Jun Eul Hwang, Ji Hoon Kim, Soo Mi Kim, Kyu Yun Jang, Sang-Bae Kim, Jae-Jun Shim, Bo Hwa Sohn
Purpose: The Hippo pathway is a tumor suppressor in the liver. However, the clinical significance of Hippo pathway inactivation in HCC is not clearly defined. We analyzed genomic data from human and mouse tissues to determine clinical relevance of Hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acad76488aad67848e1f80058140eb1
https://doi.org/10.1158/1078-0432.c.6523584.v1
https://doi.org/10.1158/1078-0432.c.6523584.v1
Data from L1 Cell Adhesion Molecule Is a Novel Therapeutic Target in Intrahepatic Cholangiocarcinoma
Autor:
Hyo Jeong Hong, Dae-Ghon Kim, Nam-Kyu Lim, Hong Seo Choi, Yeon Sung Son, Bong-Hui Kim, Young Kwan Lee, Hee Kwan Yoon, Jin Young Kim, Jae-Hyek Lee, Soung Hoo Jeon, Chun Jeih Ryu, Hyunho Yoon, Jung Whoi Lee, Shengjin Li, Jin-Man Kim, Jeong-Ki Min
Purpose: Intrahepatic cholangiocarcinoma (ICC), a highly malignant hepatobiliary cancer, has a poor prognosis and is refractory to conventional therapies. The aim of this study is to discover a novel molecular target for the treatment of ICC.Experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad753a1d43b51201e572a3469243b99
https://doi.org/10.1158/1078-0432.c.6519090.v1
https://doi.org/10.1158/1078-0432.c.6519090.v1
Autor:
Ju-Seog Lee, Yun-Yong Park, Randy L. Johnson, In-Sun Chu, Minse Cha, Manal M. Hassan, Ahmed Kaseb, Sun-Hee Leem, Dae-Ghon Kim, Yoon Jun Kim, Jeonghoon Heo, Eun Sung Park, Sung Soo Kim, Woojin Jeong, Sang-Cheol Kim, Hyun-Sung Lee, Hee-Jin Jang, Jun Eul Hwang, Ji Hoon Kim, Soo Mi Kim, Kyu Yun Jang, Sang-Bae Kim, Jae-Jun Shim, Bo Hwa Sohn
Figure S1: Significant concordance between silence of Hippo signature and YAP1 expression in human hepatocellular carcinoma (HCC); Figure S2: Venn diagram of gene lists from two different gene expression signatures; Table S1: Genes in the SOH signatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bfce4503d6f67765fb9e1523376a22
https://doi.org/10.1158/1078-0432.22457466
https://doi.org/10.1158/1078-0432.22457466
PDF file - 93K, Reagents and antibodies, construction of Cks1- and p27-overexpressing HCC cells, and construction of Cks1-, Skp2-, and IL8-knockdown HCC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf396937cc0c2cce256c86baf2ce205
https://doi.org/10.1158/0008-5472.22391397.v1
https://doi.org/10.1158/0008-5472.22391397.v1