Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Dae‐Soo Kim"'
Autor:
Jinkwon Lee, Gyeonghwa Kim, Tae‐Su Han, Eunsun Jung, Taesang Son, Kwangho Kim, Kiyoon Kwon, Yuna Roh, Tae Young Ryu, In Hwan Tae, Yunsang Kang, Byungheon Lee, Yu Rim Lee, Soo Young Park, Won Young Tak, Dae‐Soo Kim, Mi‐Young Son, Keun Hur, Hyun‐Soo Cho
Publikováno v:
Cancer Communications, Vol 44, Iss 6, Pp 705-709 (2024)
Externí odkaz:
https://doaj.org/article/e5c38409e5f94a57a6fca739ae93c61a
Autor:
Seon Ju Mun, Yeon-Hwa Hong, Yongbo Shin, Jaeseo Lee, Hyun-Soo Cho, Dae-Soo Kim, Kyung-Sook Chung, Myung Jin Son
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Genetic liver disease modeling is difficult because it is challenging to access patient tissue samples and to develop practical and relevant model systems. Previously, we developed novel proliferative and functional liver organoids from plur
Externí odkaz:
https://doaj.org/article/642e2912486f4595a8dd329a309d912c
Autor:
Anna Park, Kwang-eun Kim, Isaac Park, Sang Heon Lee, Kun-Young Park, Minkyo Jung, Xiaoxu Li, Maroun Bou Sleiman, Su Jeong Lee, Dae-Soo Kim, Jaehoon Kim, Dae-Sik Lim, Eui-Jeon Woo, Eun Woo Lee, Baek Soo Han, Kyoung-Jin Oh, Sang Chul Lee, Johan Auwerx, Ji Young Mun, Hyun-Woo Rhee, Won Kon Kim, Kwang-Hee Bae, Jae Myoung Suh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of generating heat via uncoupled respiration. Mitochondrial uncoupling protein 1 (UCP1) is activated in BAT during cold stress and dissipates mitochondrial proto
Externí odkaz:
https://doaj.org/article/8abfab449c994b11bb6233d6bda9aba7
Autor:
Kwangho Kim, Tae Young Ryu, Eunsun Jung, Tae-Su Han, Jinkwon Lee, Seon-Kyu Kim, Yu Na Roh, Moo-Seung Lee, Cho-Rok Jung, Jung Hwa Lim, Ryuji Hamamoto, Hye Won Lee, Keun Hur, Mi-Young Son, Dae-Soo Kim, Hyun-Soo Cho
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 952-964 (2023)
Abstract Epigenetic alterations, especially histone methylation, are key factors in cell migration and invasion in cancer metastasis. However, in lung cancer metastasis, the mechanism by which histone methylation regulates metastasis has not been ful
Externí odkaz:
https://doaj.org/article/27c0d4a625994a9cb996c9922caa7bad
Autor:
Ye Seul Son, Naeun Son, Won Dong Yu, Aruem Baek, Young-Jun Park, Moo-Seung Lee, Seon-Jin Lee, Dae-Soo Kim, Mi-Young Son
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundA growing body of evidence suggests that particulate matter (PM10) enters the gastrointestinal (GI) tract directly, causing the GI epithelial cells to function less efficiently, leading to inflammation and an imbalance in the gut microbiome
Externí odkaz:
https://doaj.org/article/17bc48fa6c944d408a5e812e721e49ac
Autor:
Hana Lee, Kwang Bo Jung, Ohman Kwon, Ye Seul Son, Eunho Choi, Won Dong Yu, Naeun Son, Jun Hyoung Jeon, Hana Jo, Haneol Yang, Yeong Rak Son, Chan-Seok Yun, Hyun-Soo Cho, Sang Kyu Kim, Dae-Soo Kim, Doo-Sang Park, Mi-Young Son
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Little is known about the modulatory capacity of the microbiota in early intestinal development. We examined various intestinal models that respond to gut microbial metabolites based on human pluripotent stem cell-derived human intestinal organoids (
Externí odkaz:
https://doaj.org/article/bcedc8c3adae41f9bf2188ec7de1d48b
Autor:
Jinkwon Lee, Kwangho Kim, Tae Young Ryu, Cho‐Rok Jung, Moo‐Seung Lee, Jung Hwa Lim, Kunhyang Park, Dae‐Soo Kim, Mi‐Young Son, Ryuji Hamamoto, Hyun‐Soo Cho
Publikováno v:
Molecular Oncology, Vol 15, Iss 11, Pp 2989-3002 (2021)
Dozens of histone methyltransferases have been identified and biochemically characterized, but the pathological roles of their dysfunction in human diseases such as cancer remain largely unclear. Here, we demonstrate the involvement of EHMT1, a histo
Externí odkaz:
https://doaj.org/article/fee3d286b52b48efa9d8e2ec7d01ea5b
Publikováno v:
Organoid, Vol 2 (2022)
Background Epigenetic regulation of oncogenes and tumor suppressor genes by histone methyltransferases is an important process for colon cancer growth and metastasis. Although various epigenetic modifiers have been recognized as attractive therapeuti
Externí odkaz:
https://doaj.org/article/7559a3032f3e4e43b00983b41db20659
Autor:
Mi-Ok Lee, Su-gi Lee, Cho-Rok Jung, Ye Seul Son, Jae-Woon Ryu, Kwang Bo Jung, Jun-Ho Ahn, Jung-Hwa Oh, Hyang-Ae Lee, Jung Hwa Lim, Janghwan Kim, Insu Jang, Jinhyuk Choi, Jaeeun Jung, Kunhyang Park, Byungwook Lee, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Quantitative methods to assess the quality of hPSC-derived organoids have not been developed. Here they present a prediction algorithm to assess the transcriptomic similarity between hPSC-derived organoids and the corresponding human target organs an
Externí odkaz:
https://doaj.org/article/27708e935ee5482783e2d1c6359a3d60
Autor:
Ilkyu Park, Jaeeun Jung, Sugi Lee, Kunhyang Park, Jea-Woon Ryu, Mi-Young Son, Hyun-Soo Cho, Dae-Soo Kim
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Inflammatory bowel disease (IBD) is a chronic and idiopathic inflammatory disorder of the gastrointestinal tract and comprises ulcerative colitis (UC) and Crohn’s disease (CD). Crohn’s disease can affect any part of the gastro
Externí odkaz:
https://doaj.org/article/4fd50a57e4104765b68d5778ea797f4e