Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dadu Huang"'
The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth
Autor:
Dongmei Bai, Jinfang Zhang, Tingting Li, Runlai Hang, Yong Liu, Yonglu Tian, Dadu Huang, Linglong Qu, Xiaofeng Cao, Jiafu Ji, Xiaofeng Zheng
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Perturbations in ribosome biogenesis affect development and increase cancer susceptibility. Here, the authors show that hCINAP is required for 18S rRNA processing, is highly expressed in cancers, and promotes cancer cell growth by upregulating the tr
Externí odkaz:
https://doaj.org/article/70202b76d3064669a4032452fc93fbae
The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth
Autor:
Xiaofeng Zheng, Xiaofeng Cao, Yonglu Tian, Jiafu Ji, Jinfang Zhang, Runlai Hang, Linglong Qu, Dadu Huang, Tingting Li, Yong Liu, Dongmei Bai
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Dysfunctions in ribosome biogenesis cause developmental defects and increased cancer susceptibility; however, the connection between ribosome assembly and tumorigenesis remains unestablished. Here we show that hCINAP (also named AK6) is required for