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The protein kinase LKB1 promotes self‐renewal and blocks invasiveness in glioblastoma.

Autor: Caja, Laia, Dadras, Mahsa Shahidi, Mezheyeuski, Artur, Rodrigues‐Junior, Dorival Mendes, Liu, Sijia, Webb, Anna Taylor, Gomez‐Puerto, Maria Catalina, ten Dijke, Peter, Heldin, Carl‐Henrik, Moustakas, Aristidis

Publikováno v: Journal of Cellular Physiology; Jan2022, Vol. 237 Issue 1, p743-762, 20p

The protein kinase SIK downregulates the polarity protein Par3

Autor: Vanlandewijck, Michael, Dadras, Mahsa Shahidi, Lomnytska, Marta, Mahzabin, Tanzila, Miller, Martin Lee, Busch, Christer, Brunak, Søren, Heldin, Carl-Henrik, Moustakas, Aristidis

Publikováno v: Vanlandewijck, M, Dadras, M S, Lomnytska, M, Mahzabin, T, Miller, M L, Busch, C, Brunak, S, Heldin, C-H & Moustakas, A 2018, ' The protein kinase SIK downregulates the polarity protein Par3 ', OncoTarget, vol. 9, no. 5, pp. 5716-5735 . https://doi.org/10.18632/oncotarget.23788

The multifunctional cytokine transforming growth factor β (TGFβ) controls homeostasis and disease during embryonic and adult life. TGFβ alters epithelial cell differentiation by inducing epithelial-mesenchymal transition (EMT), which involves down

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2751::19431a859620055f00b0128be3337b60
https://curis.ku.dk/portal/da/publications/the-protein-kinase-sik-downregulates-the-polarity-protein-par3(b7b09980-4482-4938-bfa3-82335b173771).html

The protein kinase SIK downregulates the polarity protein Par3.

Autor: Vanlandewijck M; Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Integrated Cardio Metabolic Center, Novum, Karolinska Institute, Huddinge, Sweden., Dadras MS; Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lomnytska M; Department of Oncology and Pathology, Karolinska Biomics Center, Karolinska Institute, Stockholm, Sweden.; Department of Obstetrics and Gynaecology, Academic Uppsala Hospital, Uppsala, Sweden., Mahzabin T; Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; School of Anatomy, Physiology and Human Biology, The University of Western Australia, Crawley, WA, Australia., Lee Miller M; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.; Cancer Research UK, Cambridge Institute, University of Cambridge, Li Ka Shing Center, Cambridge, UK., Busch C; Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden., Brunak S; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Heldin CH; Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Moustakas A; Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

Publikováno v: Oncotarget [Oncotarget] 2017 Dec 31; Vol. 9 (5), pp. 5716-5735. Date of Electronic Publication: 2017 Dec 31 (Print Publication: 2018).