Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dacia Leon"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007348 (2018)
Key innovations are disruptive evolutionary events that enable a species to escape constraints and rapidly diversify. After 15 years of the Lenski long-term evolution experiment with Escherichia coli, cells in one of the twelve populations evolved th
Externí odkaz:
https://doaj.org/article/8ef42b3361914b5884d579a1aa1f8f93
Publikováno v:
Journal of Microbiology & Biology Education, Vol 19, Iss 2 (2018)
Lack of access to reagents and equipment can make performing microbiology experiments difficult in K-12 classrooms and do-it-yourself (DIY) science settings. We demonstrate how the bacterium Sphingomonas paucimobilis can be used to synthesize gellan
Externí odkaz:
https://doaj.org/article/3145de69c90548b281dd5a403ba311c6
Autor:
Jeffrey M Skerker, Dacia Leon, Morgan N Price, Jordan S Mar, Daniel R Tarjan, Kelly M Wetmore, Adam M Deutschbauer, Jason K Baumohl, Stefan Bauer, Ana B Ibáñez, Valerie D Mitchell, Cindy H Wu, Ping Hu, Terry Hazen, Adam P Arkin
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-21 (2013)
Abstract The efficient production of biofuels from cellulosic feedstocks will require the efficient fermentation of the sugars in hydrolyzed plant material. Unfortunately, plant hydrolysates also contain many compounds that inhibit microbial growth a
Externí odkaz:
https://doaj.org/article/5b27a545429d4b08976dc36c2769d249
Publikováno v:
Nucleic Acids Research
Unwanted evolution of designed DNA sequences limits metabolic and genome engineering efforts. Engineered functions that are burdensome to host cells and slow their replication are rapidly inactivated by mutations, and unplanned mutations with unpredi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822f142a56248009606434cc99f548d9
https://doi.org/10.1101/301382
https://doi.org/10.1101/301382
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007348 (2018)
PLoS Genetics
PLoS Genetics
Key innovations are disruptive evolutionary events that enable a species to escape constraints and rapidly diversify. After 15 years of the Lenski long-term evolution experiment with Escherichia coli, cells in one of the twelve populations evolved th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c421c04df2c81654a3dc3504155ecb27
http://europepmc.org/articles/PMC5918244?pdf=render
http://europepmc.org/articles/PMC5918244?pdf=render
After 15 years of the Lenski experiment one of twelveEscherichia colipopulations evolved the ability to utilize an abundant but previously untapped carbon source, citrate. Mutations responsible for the appearance of rudimentary citrate utilization (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcea094fca8d1ddbfecb936e103b4a2c
https://doi.org/10.1101/249110
https://doi.org/10.1101/249110
Autor:
Kelly A. Markham, John Blazeck, Nijia Zhou, Hal S. Alper, Leqian Liu, Dacia Leon, Peter B. Otoupal
Publikováno v:
Metabolic Engineering. 31:102-111
Lipogenic organisms represent great starting points for metabolic engineering of oleochemical production. While previous engineering efforts were able to significantly improve lipid production in Yarrowia lipolytica, the lipogenesis landscape, especi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904b390c86740b3c256d210f5f43f2d2
https://doi.org/10.1016/j.ymben.2015.07.004
https://doi.org/10.1016/j.ymben.2015.07.004
Autor:
Sean P. Leonard, Gabriel A. Suárez, Jeffrey E. Barrick, Brian A. Renda, Benjamin R. Jack, Dacia Leon, Dennis M. Mishler
Publikováno v:
ACS Synthetic Biology. 4:939-943
Unwanted evolution can rapidly degrade the performance of genetically engineered circuits and metabolic pathways installed in living organisms. We created the Evolutionary Failure Mode (EFM) Calculator to computationally detect common sources of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a4efd3166c8401de684538e1499c88
https://doi.org/10.1021/acssynbio.5b00068
https://doi.org/10.1021/acssynbio.5b00068
Publikováno v:
Journal of Bacteriology. 197:872-881
Acinetobacter baylyi ADP1 has the potential to be a versatile bacterial host for synthetic biology because it is naturally transformable. To examine the genetic reliability of this desirable trait and to understand the potential stability of other en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9c7b5b187bcaed70918ff9c1b4511b
https://doi.org/10.1128/jb.02263-14
https://doi.org/10.1128/jb.02263-14
Autor:
Wenjun Shao, Kelly M. Wetmore, Dacia Leon, Daniel R. Tarjan, Adam P. Arkin, Jeffrey M. Skerker, Zhuchen Xu, Adam M. Deutschbauer, Morgan N. Price
Publikováno v:
Journal of bacteriology, vol 196, iss 20
Mutant phenotypes provide strong clues to the functions of the underlying genes and could allow annotation of the millions of sequenced yet uncharacterized bacterial genes. However, it is not known how many genes have a phenotype under laboratory con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557e6094ebbc325d01f1cccd44744a1c
https://escholarship.org/uc/item/78s6x9q5
https://escholarship.org/uc/item/78s6x9q5