Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dacia, Dimartino"'
Autor:
Theodore Sakellaropoulos, Catherine Do, Guimei Jiang, Giulia Cova, Peter Meyn, Dacia Dimartino, Sitharam Ramaswami, Adriana Heguy, Aristotelis Tsirigos, Jane A. Skok
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Aberrations in the capacity of DNA/chromatin modifiers and transcription factors to bind non-coding regions can lead to changes in gene regulation and impact disease phenotypes. However, identifying distal regulatory elements and connecting
Externí odkaz:
https://doaj.org/article/25fc948f3f434d049d7610ff9b16694c
Autor:
Ralf Duerr, Dacia Dimartino, Christian Marier, Paul Zappile, Guiqing Wang, Fritz François, Mila B. Ortigoza, Eduardo Iturrate, Marie I. Samanovic, Mark J. Mulligan, Adriana Heguy
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104843- (2023)
Summary: Background: High rates of vaccination and natural infection drive immunity and redirect selective viral adaptation. Updated boosters are installed to cope with drifted viruses, yet data on adaptive evolution under increasing immune pressure
Externí odkaz:
https://doaj.org/article/9a42314292244bbf8ac8b08f64d79d3b
Autor:
Simon Dellicour, Samuel L Hong, Verity Hill, Dacia Dimartino, Christian Marier, Paul Zappile, Gordon W Harkins, Philippe Lemey, Guy Baele, Ralf Duerr, Adriana Heguy
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011348 (2023)
Since the latter part of 2020, SARS-CoV-2 evolution has been characterised by the emergence of viral variants associated with distinct biological characteristics. While the main research focus has centred on the ability of new variants to increase in
Externí odkaz:
https://doaj.org/article/9a24d641a1354d4da8ae5335b19a3576
Autor:
Ralf Duerr, Hao Zhou, Takuya Tada, Dacia Dimartino, Christian Marier, Paul Zappile, Guiqing Wang, Jonathan Plitnick, Sara B. Griesemer, Roxanne Girardin, Jessica Machowski, Sean Bialosuknia, Erica Lasek-Nesselquist, Samuel L. Hong, Guy Baele, Meike Dittmann, Mila B. Ortigoza, Prithiv J. Prasad, Kathleen McDonough, Nathaniel R. Landau, Kirsten St George, Adriana Heguy
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106075- (2023)
Summary: The emergence of recombinant viruses is a threat to public health, as recombination may integrate variant-specific features that together result in escape from treatment or immunity. The selective advantages of recombinant SARS-CoV-2 isolate
Externí odkaz:
https://doaj.org/article/585eec9eafc5429bbcaa9a950f5d24d1
Autor:
Adriana Heguy, Dacia Dimartino, Christian Marier, Paul Zappile, Emily Guzman, Ralf Duerr, Guiqing Wang, Jonathan Plitnick, Alexis Russell, Daryl M. Lamson, Kirsten St. George
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 4, Pp 881-883 (2022)
Of 379 severe acute respiratory syndrome coronavirus 2 samples collected in New York, USA, we detected 86 Omicron variant sequences containing Delta variant mutation P681R. Probable explanations were co-infection with 2 viruses or contamination/ampli
Externí odkaz:
https://doaj.org/article/299b66beeb9d4dca94e9be823107f679
The Long Non-coding RNA lnc-31 Interacts with Rock1 mRNA and Mediates Its YB-1-Dependent Translation
Autor:
Dacia Dimartino, Alessio Colantoni, Monica Ballarino, Julie Martone, Davide Mariani, Johannes Danner, Astrid Bruckmann, Gunter Meister, Mariangela Morlando, Irene Bozzoni
Publikováno v:
Cell Reports, Vol 23, Iss 3, Pp 733-740 (2018)
Summary: Cytoplasmic long non-coding RNAs have been shown to act at many different levels to control post-transcriptional gene expression, although their role in translational control is poorly understood. Here, we show that lnc-31, a non-coding RNA
Externí odkaz:
https://doaj.org/article/ec1c0ffdd1764928abb6e827d776c442
Autor:
John I Hogan, Ralf Duerr, Dacia Dimartino, Christian Marier, Sarah E Hochman, Sapna Mehta, Guiqing Wang, Adriana Heguy
Publikováno v:
Clinical Infectious Diseases. 76:342-345
New mutations conferring resistance to SARS-CoV-2 therapeutics have important clinical implications. We describe the first cases of an independently acquired V792I RNA-dependent RNA polymerase mutation developing in renal transplant recipients after
Autor:
Ralf Duerr, Hao Zhou, Takuya Tada, Dacia Dimartino, Christian Marier, Paul Zappile, Guiqing Wang, Jonathan Plitnick, Sara B. Griesemer, Roxanne Girardin, Jessica Machowski, Sean Bialosuknia, Erica Lasek-Nesselquist, Samuel L. Hong, Guy Baele, Meike Dittmann, Mila B. Ortigoza, Prithiv J. Prasad, Kathleen McDonough, Nathaniel R. Landau, Kirsten St. George, Adriana Heguy
Publikováno v:
bioRxiv
SummaryBackgroundThe emergence of recombinant viruses is a threat to public health. Recombination of viral variants may combine variant-specific features that together catalyze viral escape from treatment or immunity. The selective advantages of reco
Autor:
John I, Hogan, Ralf, Duerr, Dacia, Dimartino, Christian, Marier, Sarah E, Hochman, Sapna, Mehta, Guiqing, Wang, Adriana, Heguy
The medical community currently lacks robust data regarding the incidence, prevalence, and clinical significance of mutations associated with resistance to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) therapeutics. This report describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3c84216d6151164001736415226a89
https://doi.org/10.21203/rs.3.rs-1800050/v1
https://doi.org/10.21203/rs.3.rs-1800050/v1
Autor:
Ralf Duerr, Dacia Dimartino, Christian Marier, Paul Zappile, Samuel Levine, Fritz Francois, Eduardo Iturrate, Guiqing Wang, Meike Dittmann, Jennifer Lighter, Brian Elbel, Andrea B. Troxel, Keith S. Goldfeld, Adriana Heguy
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
In 2021, Delta became the predominant SARS-CoV-2 variant worldwide. While vaccines have effectively prevented COVID-19 hospitalization and death, vaccine breakthrough infections increasingly occurred. The precise role of clinical and genomic determin