Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dace Hartmane"'
l-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function
Autor:
Angelika K. Sawicka, Dace Hartmane, Patrycja Lipinska, Ewa Wojtowicz, Wieslawa Lysiak-Szydlowska, Robert A. Olek
Publikováno v:
Nutrients, Vol 10, Iss 2, p 255 (2018)
Skeletal muscle wasting, associated with aging, may be regulated by the inflammatory cytokines as well as by insulin-like growth factor 1 (IGF-1). l-carnitine possesses anti-inflammatory properties and increases plasma IGF-1 concentration, leading to
Externí odkaz:
https://doaj.org/article/6e5ae58c402c4eb9b577df53e9519a86
Autor:
Joanna J. Samulak, Solveiga Grinberga, Osvalds Pugovics, Robert A. Olek, Dace Hartmane, Wieslawa Lysiak-Szydlowska, Angelika K. Sawicka
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Increased plasma trimethylamine N-oxide (TMAO) levels have been associated with cardiovascular diseases (CVD). L-carnitine induces TMAO elevation in human blood, and thus, it has been suggested as developing atherosclerosis. The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6605599190b82365563ef7150b84180d
Autor:
Dace Hartmane, Ieva Strele, Solveiga Grinberga, Maija Dambrova, Andrejs Erglis, Osvalds Pugovics, Gustavs Latkovskis, Edgars Liepinsh, Janis Kuka, Ilze Konrade
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 124:251-256
Recent studies have revealed strong associations between systemic trimethylamine N-oxide (TMAO) levels, atherosclerosis and cardiovascular risk. In addition, plasma L-carnitine levels in patients with high TMAO concentrations predicted an increased r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dc08eb5dc9a19f3fbbe78cb0cccd4d
https://doi.org/10.1055/s-0035-1569330
https://doi.org/10.1055/s-0035-1569330
Autor:
M. Dambrova, Solveiga Grinberga, Andrejs Erglis, Helena Cirule, E. Liepinsh, E. Makarova, L. Bondare, M. Mazule, Gustavs Latkovskis, Dace Hartmane
Aims Trimethylamine-N-oxide (TMAO) is a novel cardiovascular risk marker. We explored the association of commonly used cardiovascular medications with TMAO levels in patients and validated the identified associations in mice. Methods Detailed history
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9393b2dcec07370f72385858ed2ccac
https://europepmc.org/articles/PMC6177719/
https://europepmc.org/articles/PMC6177719/
Autor:
Maija Dambrova, Dace Hartmane, Edgars Liepinsh, Eduards Sevostjanovs, Ilze Konrade, Ieva Strele, Gustavs Latkovskis, Osvalds Pugovics, Solveiga Grinberga
Publikováno v:
Biomedical Chromatography. 29:1670-1674
An ultra-high-performance liquid chromatography-mass spectrometry (UPLC/MS/MS) method was developed and validated for the quantification of trimethylamine-N-oxide (TMAO) simultaneously with TMAO-related molecules L-carnitine and γ-butyrobetaine (GBB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::644f34a074971cee5f305256a3ddefae
https://doi.org/10.1002/bmc.3477
https://doi.org/10.1002/bmc.3477
Autor:
M. Mazule, L. Bondare, Andrejs Erglis, Maija Dambrova, E. Liepins, Dace Hartmane, A. Racicka, E. Makarova, Ilze Konrade, Gustavs Latkovskis
Publikováno v:
European Heart Journal. 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee715fff3041a248f1a6005803efb24a
https://doi.org/10.1093/eurheartj/ehx493.p5331
https://doi.org/10.1093/eurheartj/ehx493.p5331
Publikováno v:
Journal of basic microbiology. 58(1)
CntA oxygenase is a Rieske 2S-2Fe cluster-containing protein that has been previously described as able to produce trimethylamine (TMA) from carnitine, gamma-butyrobetaine, glycine betaine, and in one case, choline. TMA found in humans is exclusively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9218d1a6561a36a2a4fee410fb74c215
https://pubmed.ncbi.nlm.nih.gov/29110324
https://pubmed.ncbi.nlm.nih.gov/29110324
Autor:
Solveiga Grinberga, Edgars Liepinsh, Helena Cirule, Dace Hartmane, Elina Makarova, Olga Zharkova-Malkova, Eduards Sevostjanovs, Maija Dambrova
Publikováno v:
Basicclinical pharmacologytoxicology. 120(5)
Meldonium (3-(2,2,2-trimethylhydrazinium)propionate) is the most potent clinically used inhibitor of organic cation transporter 2 (OCTN2). Inhibition of OCTN2 leads to a decrease in carnitine and acylcarnitine contents in tissues and energy metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a1b1f50e929c081d11f4bc3208326e
https://pubmed.ncbi.nlm.nih.gov/27983775
https://pubmed.ncbi.nlm.nih.gov/27983775
Autor:
Solveiga, Grinberga, Maija, Dambrova, Gustavs, Latkovskis, Ieva, Strele, Ilze, Konrade, Dace, Hartmane, Eduards, Sevostjanovs, Edgars, Liepinsh, Osvalds, Pugovics
Publikováno v:
Biomedical chromatography : BMC. 29(11)
An ultra-high-performance liquid chromatography-mass spectrometry (UPLC/MS/MS) method was developed and validated for the quantification of trimethylamine-N-oxide (TMAO) simultaneously with TMAO-related molecules L-carnitine and γ-butyrobetaine (GBB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a066e96a3301f1cf5efcda8ba166cd36
https://pubmed.ncbi.nlm.nih.gov/25873316
https://pubmed.ncbi.nlm.nih.gov/25873316
Autor:
Zaharenko, Linda, Kalnina, Ineta, Geldnere, Kristine, Konrade, Ilze, Grinberga, Solveiga, Židzik, Jozef, Javorský, Martin, Lejnieks, Aivars, Nikitina-Zake, Liene, Fridmanis, Davids, Peculis, Raitis, Radovica-Spalvina, Ilze, Dace Hartmane, Pugovics, Osvalds, Tkáč, Ivan, Klimčáková, Lucia, Pīrāgs, Valdis, Klovins, Janis
Publikováno v:
European Journal of Endocrinology; Dec2016, Vol. 175 Issue 6, p531-540, 10p