Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dacai Xu"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Serpinc1 is a serine protease inhibitor in the coagulation cascade, but its role in tumor biology remains obscure. Here, we report an unexpected role of serpinc1 in suppression of hepatocellular carcinoma (HCC). In HCC patients, the mRNA and protein
Externí odkaz:
https://doaj.org/article/bbfec24f872f46b79240eb408d75fa2c
Autor:
Jinghong Chen, Xin Chen, Dacai Xu, Li Yang, Zhenjun Yang, Qianqian Yang, Ding Yan, Peiquan Zhang, Du Feng, Jinbao Liu
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Ubiquitin–proteasome system (UPS) and autophagy–lysosome pathway (ALP) are two major systems for protein quality control (PQC) in eukaryotic cells. Interconnectivity between these two pathways has been suggested, but the molecular detail of how t
Externí odkaz:
https://doaj.org/article/09e5948d1de44225972f2e4b66c21572
Autor:
Xin Chen, Qianqian Yang, Jinghong Chen, Peiquan Zhang, Qingtian Huang, Xiaolan Zhang, Li Yang, Dacai Xu, Chong Zhao, Xuejun Wang, Jinbao Liu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 2, Pp 780-797 (2018)
Background/Aims: The ubiquitin proteasome system (UPS) is responsible for the degradation of most intracellular proteins, and proteasomal deubiquitinases (DUBs) have recently been highlighted as novel anticancer targets. It is well documented that co
Externí odkaz:
https://doaj.org/article/fbb04df17ff54b529ec415672a1ba0b4
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Serpinc1 is a serine protease inhibitor in the coagulation cascade, but its role in tumor biology remains obscure. Here, we report an unexpected role of serpinc1 in suppression of hepatocellular carcinoma (HCC). In HCC patients, the mRNA and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca26802640888ea980c4c2dd29f9c4e
https://www.frontiersin.org/articles/10.3389/fonc.2021.738607/full
https://www.frontiersin.org/articles/10.3389/fonc.2021.738607/full
Autor:
Dacai Xu, Xin Chen, Peiquan Zhang, Chong Zhao, Jinbao Liu, Xuejun Wang, Li Yang, Qianqian Yang, Xiaolan Zhang, Qingtian Huang, Jinghong Chen
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 2, Pp 780-797 (2018)
Background/Aims: The ubiquitin proteasome system (UPS) is responsible for the degradation of most intracellular proteins, and proteasomal deubiquitinases (DUBs) have recently been highlighted as novel anticancer targets. It is well documented that co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416c7d93fcda788599815e564563ebd4
https://www.karger.com/Article/FullText/493041
https://www.karger.com/Article/FullText/493041
Publikováno v:
J Bone Miner Metab
INTRODUCTION: The periosteum has a bilayered structure that surrounds cortical bone. The outer layer is rich in connective tissue and fibroblasts, while the inner layer in contact with the cortical surface of the bone predominantly consists of osteob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e53c50d7928bbb9514c9f5945b9bc0a
https://pubmed.ncbi.nlm.nih.gov/32415375
https://pubmed.ncbi.nlm.nih.gov/32415375
Autor:
Jinghong Chen, Xin Chen, Dacai Xu, Li Yang, Zhenjun Yang, Qianqian Yang, Ding Yan, Peiquan Zhang, Du Feng, Jinbao Liu
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Ubiquitin–proteasome system (UPS) and autophagy–lysosome pathway (ALP) are two major systems for protein quality control (PQC) in eukaryotic cells. Interconnectivity between these two pathways has been suggested, but the molecular detail of how t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61d8f3eb02260f262b1207c4bf06831
https://pubmed.ncbi.nlm.nih.gov/32292717
https://pubmed.ncbi.nlm.nih.gov/32292717
Publikováno v:
Molecular Medicine Reports. 2015, Vol. 12 Issue 6, p7963-7970. 8p.
Publikováno v:
Molecular Medicine Reports
Hepatocellular carcinoma (HCC) is the leading cause of cancer-associated mortality worldwide; however, only limited therapeutic treatments are currently available. The present study aimed to investigate the effects of cannabinoids as novel therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4f54a6a9ae0301381ba5ec2c5cbe53
https://doi.org/10.3892/mmr.2015.4477
https://doi.org/10.3892/mmr.2015.4477
Autor:
Li Yu, Xiaoli Wang, Jinghong Chen, Yuning Liao, Jinbao Liu, Xianping Shi, Xiaoying Lan, Ningning Liu, Dacai Xu, Xiaofen Li, Mingxing Guo, Chang E. Zhang, Siyan Liao, Yuqiang Nie, Hongbiao Huang, Chong Zhao, Ping Zhou, Xuejun Wang, Haoyu Chen, Xin Chen
Publikováno v:
Cell Death & Disease
The molecular mechanism underlying bilirubin neurotoxicity remains obscure. Ubiquitin–proteasome system-mediated proteolysis is pivotal to virtually all cellular processes and cell survival. Here we report for the first time that bilirubin at a cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19df8474fa818024ac775e9060d2bffe
https://pubmed.ncbi.nlm.nih.gov/28617443
https://pubmed.ncbi.nlm.nih.gov/28617443