Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Dac-Trung Nguyen"'
Autor:
Dac Trung Nguyen, Thi Loan Nguyen, Allison Olmsted, Thi Hong Duong, Hong Mai Hoang, Lien Huong Nguyen, Mahamoudou Ouattara, Jennifer Milucky, Fernanda C. Lessa, Thi Trang Dai Vo, Van Thanh Phan, Thi Hien Anh Nguyen, Nguyen My Nguyet Pham, Huu Khanh Truong, Thi Quynh Tram Phan, Thi Hong Hoa Bui, Van Khang Pham, Makiko Iijima, Binh Le, Lindsay Kim, Jennifer Loo Farrar
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Streptococcus pneumoniae (S. pneumoniae), Haemophilus influenzae (H. influenzae), and Neisseria meningitidis (N. meningitidis) are leading causes of childhood bacterial meningitis and preventable by vaccines. The aim of this hospi
Externí odkaz:
https://doaj.org/article/90e6c4f2c755447696c860675f309117
Akademický článek
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Publikováno v:
Journal of Biomedical Semantics, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Background The Genetic and Rare Diseases (GARD) Information Center was established by the National Institutes of Health (NIH) to provide freely accessible consumer health information on over 6500 genetic and rare diseases. As the cumulative
Externí odkaz:
https://doaj.org/article/3fabd8e51dab44b9bcfa99e39bed536a
Autor:
Pranav Shah, Vishal B. Siramshetty, Alexey V. Zakharov, Noel T. Southall, Xin Xu, Dac-Trung Nguyen
Publikováno v:
Journal of Cheminformatics, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Over the last few decades, chemists have become skilled at designing compounds that avoid cytochrome P (CYP) 450 mediated metabolism. Typical screening assays are performed in liver microsomal fractions and it is possible to overlook the con
Externí odkaz:
https://doaj.org/article/1625cd47c9774f6a95d3d18250ef445d
Autor:
Yu Lin, Saurabh Mehta, Hande Küçük-McGinty, John Paul Turner, Dusica Vidovic, Michele Forlin, Amar Koleti, Dac-Trung Nguyen, Lars Juhl Jensen, Rajarshi Guha, Stephen L. Mathias, Oleg Ursu, Vasileios Stathias, Jianbin Duan, Nooshin Nabizadeh, Caty Chung, Christopher Mader, Ubbo Visser, Jeremy J. Yang, Cristian G. Bologa, Tudor I. Oprea, Stephan C. Schürer
Publikováno v:
Journal of Biomedical Semantics, Vol 8, Iss 1, Pp 1-16 (2017)
Abstract Background One of the most successful approaches to develop new small molecule therapeutics has been to start from a validated druggable protein target. However, only a small subset of potentially druggable targets has attracted significant
Externí odkaz:
https://doaj.org/article/c7f21332499a4a20a9198a03f5457353
Publikováno v:
EUREKA: Physics and Engineering. :46-56
The design capability, strength, and structural rigidity provided by tube hydroforming (THF) are successfully used in many applications to produce high-strength parts and assemblies with improved mechanical properties, optimized service life, and wei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8549f8941daebc03d85014faa3fa7a47
https://doi.org/10.21303/2461-4262.2022.002256
https://doi.org/10.21303/2461-4262.2022.002256
Autor:
Ruili Huang, Ivan Grishagin, Yuhong Wang, Tongan Zhao, Jon Greene, John C. Obenauer, Deborah Ngan, Dac-Trung Nguyen, Rajarshi Guha, Ajit Jadhav, Noel Southall, Anton Simeonov, Christopher P. Austin
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Chemical genomics aims to comprehensively define, and ultimately predict, the effects of small molecule compounds on biological systems. Chemical activity profiling approaches must consider chemical effects on all pathways operative in mammalian cell
Externí odkaz:
https://doaj.org/article/6c89eecfdfae41d0a777dc3ead3d8736
Autor:
Keith J Kelleher, Timothy K Sheils, Stephen L Mathias, Jeremy J Yang, Vincent T Metzger, Vishal B Siramshetty, Dac-Trung Nguyen, Lars Juhl Jensen, Dušica Vidović, Stephan C Schürer, Jayme Holmes, Karlie R Sharma, Ajay Pillai, Cristian G Bologa, Jeremy S Edwards, Ewy A Mathé, Tudor I Oprea
Publikováno v:
Kelleher, K J, Sheils, T K, Mathias, S L, Yang, J J, Metzger, V T, Siramshetty, V B, Nguyen, D-T, Jensen, L J, Vidovic, D, Schurer, S C, Holmes, J, Sharma, K R, Pillai, A, Bologa, C G, Edwards, J S, Mathe, E A & Oprea, T 2023, ' Pharos 2023 : an integrated resource for the understudied human proteome ', Nucleic Acids Research, vol. 51, no. D1, gkac1033, pp. D1405-D1416 . https://doi.org/10.1093/nar/gkac1033
The Illuminating the Druggable Genome (IDG) project aims to improve our understanding of understudied proteins and our ability to study them in the context of disease biology by perturbing them with small molecules, biologics, or other therapeutic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d65450ea96a731b4d232b473fbf4326
https://curis.ku.dk/portal/da/publications/pharos-2023(f032f17b-c49b-4c10-9eb3-36e30874c00f).html
https://curis.ku.dk/portal/da/publications/pharos-2023(f032f17b-c49b-4c10-9eb3-36e30874c00f).html
Publikováno v:
Acta Metallurgica Slovaca. 27:72-76
The effect of plastic deformation upon the grain structure and mechanical properties of Al-Cu-Mg-Mn alloy tubes under upsetting was investigated. It was found that plastic deformation techniques such as cold upsetting can overcome the disadvantages o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd445e6b4161d51e505db8e010a44dff
https://doi.org/10.36547/ams.27.2.812
https://doi.org/10.36547/ams.27.2.812
Autor:
Alexey V. Zakharov, Vishal B. Siramshetty, Natalia J. Martinez, Noel Southall, Dac-Trung Nguyen, Anton Simeonov
Publikováno v:
Journal of Chemical Information and Modeling. 60:6007-6019
The rise of novel artificial intelligence (AI) methods necessitates their benchmarking against classical machine learning for a typical drug-discovery project. Inhibition of the potassium ion channel, whose alpha subunit is encoded by the human ether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2216ef035ec317257aa5dee60a588842
https://doi.org/10.1021/acs.jcim.0c00884
https://doi.org/10.1021/acs.jcim.0c00884