Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dabbugoddu Brahmaiah"'
Autor:
Battini Veeraiah, Kishore Ramineni, Dabbugoddu Brahmaiah, Nangunoori Sampath Kumar, Hélène Solhi, Rémy Le Guevel, Chada Raji Reddy, Frédéric Justaud, René Grée
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 2592-2598 (2024)
In this paper, we report a short and efficient synthesis of novel N-arylbenzo[h]quinazoline-2-amines. We have prepared a focused library of nineteen representative examples which have been submitted to cytotoxicity assays against a representative pan
Externí odkaz:
https://doaj.org/article/c0156c58495f466e9f62d5f36cb9d362
Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases
Autor:
Dabbugoddu Brahmaiah, Anagani Kanaka Durga Bhavani, Pasula Aparna, Nangunoori Sampath Kumar, Hélène Solhi, Rémy Le Guevel, Blandine Baratte, Thomas Robert, Sandrine Ruchaud, Stéphane Bach, Surender Singh Jadav, Chada Raji Reddy, Paul Mosset, Nicolas Gouault, Nicolas Levoin, René Grée
Publikováno v:
Molecules, Vol 27, Iss 19, p 6149 (2022)
Three series of our lead CLK1 inhibitor DB18 have been designed, synthetized and tested against CLKs and DYRK1A kinases. Their cytotoxicity was subsequently measured on seven representative cancer cell lines. Guided by docking experiments, we focused
Externí odkaz:
https://doaj.org/article/8f6310fc059c4f1d98e8bd66d3c3586f
Autor:
Dabbugoddu Brahmaiah, Anagani Kanaka Durga Bhavani, Pasula Aparna, Nangunoori Sampath Kumar, Hélène Solhi, Rémy Le Guevel, Blandine Baratte, Sandrine Ruchaud, Stéphane Bach, Paul Mosset and René Grée
Publikováno v:
ARKIVOC, Vol 2019, Iss 5, Pp 96-107 (2019)
Externí odkaz:
https://doaj.org/article/e03f44f467e145e399408472f9a11621