Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daan Peric-Hupkes"'
Autor:
Pradeep Kumar, Omid Gholamalamdari, Yang Zhang, Liguo Zhang, Anastassiia Vertii, Tom van Schaik, Daan Peric-Hupkes, Takayo Sasaki, David M. Gilbert, Bas van Steensel, Jian Ma, Paul D. Kaufman, Andrew S. Belmont
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Genome differential positioning within interphase nuclei remains poorly explored. We extended and validated Tyramide Signal Amplification (TSA)-seq to map genomic regions near nucleoli and pericentric heterochromatin in four human cell lines
Externí odkaz:
https://doaj.org/article/cfb961e8f2924eb693d3f3d3481fa6c4
Autor:
Tom van Schaik, Ning Qing Liu, Stefano G. Manzo, Daan Peric-Hupkes, Elzo de Wit, Bas van Steensel
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-26 (2022)
Abstract Background Lamina-associated domains (LADs) are large genomic regions that are positioned at the nuclear lamina. It has remained largely unclear what drives the positioning and demarcation of LADs. Because the insulator protein CTCF is enric
Externí odkaz:
https://doaj.org/article/b6ade8f819f9451eab87ce8b9171ce53
Publikováno v:
EMBO Reports, 21(11):e50636. Wiley-Blackwell
EMBO Reports
EMBO Reports
In mammalian interphase nuclei, more than one thousand large genomic regions are positioned at the nuclear lamina (NL). These lamina‐associated domains (LADs) are involved in gene regulation and may provide a backbone for the folding of interphase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a762e40e13abce67f908ae6651173332
https://doi.org/10.15252/embr.202050636
https://doi.org/10.15252/embr.202050636
Autor:
Lodewyk F. A. Wessels, Jean-Bernard Beaudry, Ludo Pagie, Bas van Steensel, Jop Kind, Manolis Kellis, Daan Peric-Hupkes, Wouter Meuleman, Marcel J. T. Reinders
Publikováno v:
Genome Research
In metazoans, the nuclear lamina is thought to play an important role in the spatial organization of interphase chromosomes, by providing anchoring sites for large genomic segments named lamina-associated domains (LADs). Some of these LADs are cell-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704d86c17d45b89c943c4cbde62c2de9
https://doi.org/10.1101/gr.141028.112
https://doi.org/10.1101/gr.141028.112
Autor:
Maarten van Lohuizen, Bas van Steensel, Lodewyk F. A. Wessels, Wouter Meuleman, Irina Solovei, Stefan Gräf, Ron M. Kerkhoven, Sophia W.M. Bruggeman, Marcel J. T. Reinders, Paul Flicek, Wim Brugman, Ludo Pagie, Daan Peric-Hupkes
Publikováno v:
Molecular cell. 38(4)
The three-dimensional organization of chromosomes within the nucleus and its dynamics during differentiation are largely unknown. To visualize this process in molecular detail, we generated high-resolution maps of genome-nuclear lamina interactions d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fef1f8b2f304d3d180bc9f4f643add
https://pubmed.ncbi.nlm.nih.gov/20569682
https://pubmed.ncbi.nlm.nih.gov/20569682