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of 5
pro vyhledávání: '"Daan M.F. van Aalten"'
A mouse model for functional dissection of TAB1 O-GlcNAcylation [version 2; peer review: 2 approved]
Publikováno v:
Wellcome Open Research, Vol 4 (2020)
Background: O-GlcNAcylation is a posttranslational modification associated with various physiological and pathophysiological processes including diabetes, cancer, neurodegeneration and inflammation. However, the biological mechanisms underlying the r
Externí odkaz:
https://doaj.org/article/4133d4e5ff3d4382856f94b72d96b2eb
Autor:
Kaizhou Yan, Mathew Stanley, Bartosz Kowalski, Olawale G. Raimi, Andrew T. Ferenbach, Pingzhen Wei, Wenxia Fang, Daan M.F. van Aalten
Publikováno v:
The Journal of biological chemistry. 298(6)
Aspergillus fumigatus is the causative agent of invasive aspergillosis, an infection with mortality rates of up to 50%. The glucan-rich cell wall of A. fumigatus is a protective structure that is absent from human cells and is a potential target for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4462826f06050dc8780b152d8f82999
https://pubmed.ncbi.nlm.nih.gov/35504355
https://pubmed.ncbi.nlm.nih.gov/35504355
Autor:
Michaela Fenckova, Villo Muha, Daniel Mariappa, Marica Catinozzi, Ignacy Czajewski, Laura E.R. Blok, Andrew T. Ferenbach, Erik Storkebaum, Annette Schenck, Daan M.F. van Aalten
O-GlcNAcylation is a reversible co-/post-translational modification involved in a multitude of cellular processes. The addition and removal of O-GlcNAc modification is controlled by two conserved enzymes, O-GlcNAc transferase (OGT) and O-GlcNAc hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13ae0679cec3b454ef9425b0c9506093
https://doi.org/10.1101/2022.01.10.475726
https://doi.org/10.1101/2022.01.10.475726
Publikováno v:
Biochemical Journal. 358:287-294
Phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P3] and its immediate breakdown product PtdIns(3,4)P2 function as second messengers in growth factor- and insulin-induced signalling pathways. One of the ways that these 3-phosphoinositides are k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9e033f8ff00646ec65755784cf226d0
https://doi.org/10.1042/bj3580287
https://doi.org/10.1042/bj3580287
Autor:
Milburn, Christine C., Boudeau, Jerome, Deak, Maria, Alessi, Dario R., Daan M.F. van Aalten, Dario R.
Publikováno v:
Nature Structural & Molecular Biology; Feb2004, Vol. 11 Issue 2, p193-200, 8p