Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Daan J. Touw"'
Autor:
Daniël H. Swart, Martin de Haan, Jasper Stevens, Rob H. Henning, Sovan Adel, Adrianus C. van der Graaf, Nadir Ulu, Daan J. Touw, Guido Krenning
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 345-355 (2024)
Noncommunicable Chronic Diseases (NCD) are a socioeconomic burden and considered one of the major health challenges for coming decades. Mitochondrial dysfunction has been implicated mechanistically in their pathophysiology. Therefore, targeting mitoc
Externí odkaz:
https://doaj.org/article/b8f0e0d668de4738b59950a932a68715
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116865- (2024)
Externí odkaz:
https://doaj.org/article/989542cb311f4ac9aee9707a4b595a0e
Autor:
Frank Klont, Marieke A.J. Hof, Fleur B. Nijdam, Daan J. Touw, Stephan J.L. Bakker, Gérard Hopfgartner, Jos G.W. Kosterink, Eelko Hak
Publikováno v:
Pharmacological Research, Vol 204, Iss , Pp 107191- (2024)
Externí odkaz:
https://doaj.org/article/aff49a3d4b9948b58c6e094a3e7a30d0
Publikováno v:
Therapeutic Advances in Psychopharmacology, Vol 14 (2024)
This case report examines the possible correlation between the clozapine/norclozapine ratio and the occurrence of constipation and paralytic ileus. We present the case of a 42-year-old patient diagnosed with schizoaffective disorder undergoing clozap
Externí odkaz:
https://doaj.org/article/4a92e209edfb4874b00fdf23e22b04ca
Autor:
Daphne Den Besten-Bertholee, Daan J. Touw, Elvera A. Damer, Paola Mian, Peter G. J. Ter Horst
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectivesThis study aimed to investigate the plasma and breastmilk concentrations for sertraline, citalopram and paroxetine for assessment of the Milk/Plasma (M/P) ratio and Absolute Infant Dose (AID), and to determine actual infant drug exposure th
Externí odkaz:
https://doaj.org/article/726eeac36870422a8c260d0a7bb6d2e2
Autor:
Gerke Ariaans, Jiske F. Tiersma, Bernardus Evers, Albert Gerding, Stijn J.H. Waaijer, Remco A. Koster, Daan J. Touw, Barbara M. Bakker, Dirk-Jan Reijngoud, Steven de Jong, Mathilde Jalving
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116362- (2024)
Reprogrammed metabolism is a hallmark of cancer, but notoriously difficult to target due to metabolic plasticity, especially in response to single metabolic interventions. Combining mTOR inhibitor everolimus and mitochondrial complex 1 inhibitor metf
Externí odkaz:
https://doaj.org/article/82149ce319114b31b253696077747fef
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 13, p 3692 (2024)
Metformin is the most widely used drug in type 2 diabetes. Regular metformin use has been associated with changes in concentrations of amino acids. In the present study, we used valid stable-isotope labeled GC-MS methods to measure amino acids and me
Externí odkaz:
https://doaj.org/article/c1c13e4ed0934097ae77d875da18c8a6
Autor:
Lisanne E. N. Manson, Sander J. Delwig, Jos J. M. Drabbels, Daan J. Touw, Aiko P. J. De Vries, Dave L. Roelen, Henk-Jan Guchelaar
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Specific alleles in human leukocyte antigens (HLAs) are associated with an increased risk of developing drug hypersensitivity reactions induced by abacavir, allopurinol, carbamazepine, oxcarbazepine, phenytoin, lamotrigine, or flucloxac
Externí odkaz:
https://doaj.org/article/230f6020c8444837b368e8adcb58c81e
Autor:
Eerde H. Weening, Ali A. Al-Mubarak, Martin M. Dokter, Kenneth Dickstein, Chim C. Lang, Leong L. Ng, Marco Metra, Dirk J. van Veldhuisen, Daan J. Touw, Rudolf A. de Boer, Ron T. Gansevoort, Adriaan A. Voors, Stephan J. L. Bakker, Peter van der Meer, Nils Bomer
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Serum selenium levels have been associated with the incidence of heart failure (HF) and signs of the metabolic syndrome. In addition, notable differences have been reported between males and females in food intake and micronutrien
Externí odkaz:
https://doaj.org/article/0e391b3e786140c3859e2ca8f1016731
Autor:
Miranda Visser, Willemien F. J. Hof, Astrid M. Broek, Amanda van Hoek, Joyce J. de Jong, Daan J. Touw, Bart G. J. Dekkers
Publikováno v:
Toxins, Vol 16, Iss 2, p 67 (2024)
Introduction: Amanita phalloides poisoning is a serious health problem with a mortality rate of 10–40%. Poisonings are characterized by severe liver and kidney toxicity. The effect of Amanita phalloides poisonings on hematological parameters has no
Externí odkaz:
https://doaj.org/article/ff67d50e11674445adc2402708f0ee93