Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Autor: Mina Ryten, Daniah Trabzuni, J. Ding, Bart Post, Albert Hofman, Jean-Charles Lambert, Olaf Riess, Michele T.M. Hu, Andrew B. Singleton, Stephen Sawcer, X. Huang, Caroline H. Williams-Gray, H. R. Zielke, C Smith, Peter Lichtner, B.P.C. van de Warrenburg, Bernard Ravina, F. Durif, Ellen Sidransky, Mike A. Nalls, Karen E. Morrison, J. R. Gibbs, Robert L. Johnson, Peter Heutink, David J. Burn, Michael Bonin, Sarah Edkins, T. Gasser, Luigi Ferrucci, H. Chau, Sampath Arepalli, Chris C. A. Spencer, Yoav Ben-Shlomo, Honglei Chen, Caroline M. Tanner, Zoltán Bochdanovits, Ruth Chia, Heiko Huber, Kari Stefansson, Dena G. Hernandez, Jean-Marc Taymans, Veerle Baekelandt, Iakov N. Rudenko, Evy Lobbestael, Huw R. Morris, A. Goate, C. Moorby, Lois E. Greene, Manu Sharma, Emma Gray, Ira Shoulson, Janet Brooks, Juan C. Troncoso, K. Shaw, Laura Civiero, Alessandra Biffi, Hans Scheffer, Matthew Moore, Alan B. Zonderman, S. Sveinbjornsdottir, Avazeh Tashakkori-Ghanbaria, Jean-Christophe Corvol, Vincent Plagnol, H. Petursson, Alice Kaganovich, M M Wickremaratchi, Nigel Williams, Thomas Foltynie, Henk W. Berendse, P. Damier, A. Strange, J. M. Cooper, Simon C. Potter, Patricia Limousin, Jiali Gao, Sophie Winder-Rhodes, M. Van Der Brug, Marie Vidailhet, Elisa Greggio, Nicholas W. Wood, Kevin Talbot, M. R. Cookson, Johanna Huttenlocher, J.J. van Hilten, Dan L. Longo, Alisdair McNeill, François Tison, K.D. van Dijk, David N. Hauser, Allissa Dillman, Suneil K. Kalia, Lorraine V. Kalia, Patrick F. Chinnery, Alexis Brice, Kelechi Ndukwe, J. F. Dartigues, M. Gardner, Mohamad Saad, Palmi V. Jonsson, Kailash P. Bhatia, Roger A. Barker, André G. Uitterlinden, Maria Martinez, R. Walker, Elisa Majounie, Fernando Rivadeneira, Joel S. Perlmutter, Panagiotis Deloukas, Bryan J. Traynor, Ese E. Mudanohwo, Grisel Lopez, UM Sheerin, Joanne D. Stockton, Thomas Illig, Andres M. Lozano, Rita Guerreiro, David T. Dexter, Andrew J. Lees, Sean Chong, Gavin Hudson, Cordelia Langford, Günther Deuschl, Ravindran Kumaran, Janice L. Holton, Tamas Revesz, B.R. Bloem, Alexandra Beilina, Clare Elizabeth Harris, Daniela Berg, Anthony H.V. Schapira, Suzanne Lesage, Sean S. O'Sullivan, Albert R. Hollenbeck, James A. Pearson, R. M. A. de Bie, Delia Lorenz, Sarah E. Hunt, Richard O'Brien, Gavin Charlesworth, Maciej B. Olszewski, Stacy Steinberg, Kathrin Brockmann, Carl E Clarke, Patrizia Rizzu, Claudia Schulte, Hreinn Stefansson, Daan C. Velseboer, Omar Gustafsson, Jonathan R. Evans, Alexandra Durr, Javier Simón-Sánchez, Pierre Pollak, H. Z. Munchen, Jose Bras, Carl Counsell, John Hardy

Publikováno v: Proceedings of the National Academy of Sciences, 111(7), 2626-2631
Proceedings of the National Academy of Sciences USA, 111, 2626-31
Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2626-2631. National Academy of Sciences
Proc. Natl. Acad. Sci. U.S.A. 111, 2626-2631 (2014)
Proceedings of the National Academy of Sciences USA, 111, 7, pp. 2626-31

Item does not contain fulltext Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD. Using protein-protein interaction arrays, we identified BCL2-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f039110c8ce3d814891d0913e28b739c
https://doi.org/10.1073/pnas.1318306111

Development and external validation of a prognostic model in newly diagnosed Parkinson disease

Autor: Bart Post, Sarah L Mason, Ben Schmand, Thomas Foltynie, Roger A. Barker, Caroline H. Williams-Gray, Daan C. Velseboer, Jonathan R. Evans, Luuk Wieske, Rob J. de Haan, Rob M.A. de Bie

Publikováno v: Neurology, 86(11), 986-993. Lippincott Williams & Wilkins
Neurology, 86, 11, pp. 986-93
Neurology, 86(11), 986-993. Lippincott Williams and Wilkins
Neurology, 86, 986-93

Item does not contain fulltext OBJECTIVE: To develop a prognostic model to predict disease outcomes in individual patients with Parkinson disease (PD) and perform an external validation study in an independent cohort. METHODS: Model development was d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b18d4be5fcd29924305b06edc8f60f
https://dare.uva.nl/personal/pure/en/publications/development-and-external-validation-of-a-prognostic-model-in-newly-diagnosed-parkinson-disease(93fa54e8-f5bc-4b95-9b92-0ca398bbc672).html

Evolution of mild cognitive impairment in Parkinson disease

Autor: Dino Muslimovic, Daan C. Velseboer, Johannes D. Speelman, R. M. A. de Bie, Ben Schmand, Mark Broeders

Publikováno v: Neurology, 81(4), 346-352. Lippincott Williams & Wilkins
Neurology, 81(4), 346-352. Lippincott Williams and Wilkins

Objective: We examined the development of Parkinson disease (PD)-mild cognitive impairment (MCI) in patients with newly diagnosed PD over 5 years using recently proposed consensus criteria,and we assessed the reliability of the criteria.Methods: Pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53bc013bda4c24a5ccd2538963de0b88
https://pubmed.ncbi.nlm.nih.gov/23794682

Genome-wide association study confirms extant PD risk loci among the Dutch

Autor: Sampath Arepalli, Zoltán Bochdanovits, Rob M.A. de Bie, Bart P.C. van de Warrenburg, Albert Hofman, Bart Post, Peter Heutink, Fernando Rivadeneira, Andrew B. Singleton, Dena G. Hernandez, Hans Scheffer, Jacobus J. van Hilten, Karin van Dijk, B.R. Bloem, Daan C. Velseboer, Henk W. Berendse, Patrizia Rizzu, André G. Uitterlinden, Javier Simón-Sánchez

Publikováno v: Simon-Sanchez, J, van Hilten, J J, van de Warrenburg, B, Post, B, Berendse, H W, Arepalli, S, Hernandez, D G, de Bie, R M A, Velseboer, D, Scheffer, H, Bloem, B, van Dijk, K D, Rivadeneira, F, Hofman, A, Uitterlinden, A G, Rizzu, P, Bochdanovits, Z, Singleton, A B & Heutink, P 2011, ' Genome-wide association study confirms extant PD risk loci among the Dutch ', European Journal of Human Genetics, vol. 19, no. 6, pp. 655-661 . https://doi.org/10.1038/ejhg.2010.254
European Journal of Human Genetics, 19, 655-61
European Journal of Human Genetics, 19(6), 655-661. Nature Publishing Group
European Journal of Human Genetics, 19(6), 655-661
European journal of human genetics, 19(6), 655-661. Nature Publishing Group
European Journal of Human Genetics, 19, 6, pp. 655-61

In view of the population-specific heterogeneity in reported genetic risk factors for Parkinson's disease (PD), we conducted a genome-wide association study (GWAS) in a large sample of PD cases and controls from the Netherlands. After quality control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31aeaba6e660fbed1a1d0b0fc4b049e2
https://research.vu.nl/en/publications/d9194a9e-7750-462b-b3a1-37034d688dab

Patient perception of deep brain stimulation hardware

Autor: P. Richard Schuurman, Daan C. Velseboer, Rob M.A. de Bie, Pepijn van den Munckhof, Maria Fiorella Contarino, Violet Laurent, Olivier van der Veer, Marije N. Scholten

Publikováno v: Movement Disorders. 28:1754-1755

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cbc713c776621ec35335cee77ab7d08
https://doi.org/10.1002/mds.25439