Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daan, Ren"'
Publikováno v:
J Am Chem Soc
Oxazinomycin is a C-nucleoside natural product with antibacterial and antitumor activities. In addition to the characteristic C-glycosidic linkage shared with other C-nucleosides, oxazinomycin also features a structurally unusual 1,3-oxazine moiety,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf9a840ce3e039561da6113196e3296
https://doi.org/10.1021/jacs.2c04080
https://doi.org/10.1021/jacs.2c04080
Publikováno v:
Natural Product Reports.
This review summarizes the chemistry of S-adenosylmethionine dependent enzymes that goes beyond methylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c3252196488084e50d26c96bd2c8479
https://doi.org/10.1039/d2np00086e
https://doi.org/10.1039/d2np00086e
Autor:
Mark W. Ruszczycky, Minje Kim, Hung-wen Liu, Yasushi Ogasawara, Shao-An Wang, Yeonjin Ko, Daan Ren
Publikováno v:
Proceedings of the National Academy of Sciences. 117:10265-10270
Coformycin and pentostatin are structurally related N-nucleoside inhibitors of adenosine deaminase characterized by an unusual 1,3-diazepine nucleobase. Herein, the cof gene cluster responsible for coformycin biosynthesis is identified. Reconstitutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b9c1d99286f6f697e621a97ac111135
https://doi.org/10.1073/pnas.2000111117
https://doi.org/10.1073/pnas.2000111117
Publikováno v:
Angewandte Chemie International Edition. 58:16512-16516
C-Nucleosides are characterized by a C-C rather than a C-N linkage between the heterocyclic base and the ribofuranose ring. While the biosynthesis of pseudouridine-C-nucleosides has been studied, less is known about the pyrazole-C-nucleosides such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8c09b52aae082dd50763246b8b8120
https://doi.org/10.1002/anie.201910356
https://doi.org/10.1002/anie.201910356
Publikováno v:
Angew Chem Int Ed Engl
Showdomycin is a C-nucleoside bearing an electrophilic maleimide base. Herein, the biosynthetic pathway of showdomycin is presented. The initial stages of the pathway involve non-ribosomal peptide synthetase (NRPS) mediated assembly of a 2-amino-1H-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f73e50923fdcf5f6cb7b5eec38a1c4d
https://pubmed.ncbi.nlm.nih.gov/34048627
https://pubmed.ncbi.nlm.nih.gov/34048627
Autor:
Daan, Ren, Mark W, Ruszczycky, Yeonjin, Ko, Shao-An, Wang, Yasushi, Ogasawara, Minje, Kim, Hung-Wen, Liu
Publikováno v:
Proc Natl Acad Sci U S A
Coformycin and pentostatin are structurally related N-nucleoside inhibitors of adenosine deaminase characterized by an unusual 1,3-diazepine nucleobase. Herein, the cof gene cluster responsible for coformycin biosynthesis is identified. Reconstitutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5eab12d4c6e4f183ac2941c369b6d125
https://pubmed.ncbi.nlm.nih.gov/32350138
https://pubmed.ncbi.nlm.nih.gov/32350138
Publikováno v:
Asian Journal of Organic Chemistry. 6:414-417
A practical and efficient method has been developed for the preparation of polysubstituted furans using a visible-light-promoted photoredox neutral approach. The one-pot fashion including radical cyclization/deprotection/aromatization reaction sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb5d78cb2a05f926ca7c9385d8b95dd
https://doi.org/10.1002/ajoc.201600489
https://doi.org/10.1002/ajoc.201600489
Publikováno v:
Asian Journal of Organic Chemistry. 3:1317-1325
A practical and environmentally friendly strategy for the preparation of fused quinoline and quinoxaline derivatives has been developed, enabled by domino radical triple bond insertions. These reactions have very high regioselectivity and can be carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::234a8300c917acb313cc1ce0023870c9
https://doi.org/10.1002/ajoc.201402222
https://doi.org/10.1002/ajoc.201402222
Publikováno v:
Chemical record (New York, N.Y.). 17(8)
Visible-light photoredox catalysis has been successfully used in the functionalization of inert C-H bonds including C(sp2 )-H bonds of arenes and C(sp3 )-H bonds of aliphatic compounds over the past decade. These transformations are typically promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e973269b710bf5aa58ec31cc646ab49
https://pubmed.ncbi.nlm.nih.gov/28074599
https://pubmed.ncbi.nlm.nih.gov/28074599
Publikováno v:
ChemInform. 47
A visible-light-promoted chloramination of olefins is reported. N-Chlorosulfonamides serve as both nitrogen and chlorine sources. These reactions provide a simple, efficient, regioselective, and atom-economical method for the preparation of vicinal h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97dd46a7999904816b72322bed17ee92
https://doi.org/10.1002/chin.201609109
https://doi.org/10.1002/chin.201609109