Zobrazeno 1 - 10
of 12
pro vyhledávání: '"DaShawn A. Hickman"'
Autor:
Anirban Sen Gupta, Stephanie Huang, Michael Sun, Norman F. Luc, DaShawn A. Hickman, Kenji Miyazawa, Yifeng Ma, Ankush Banerjee, Ujjal D. S. Sekhon, Aditya Girish
Publikováno v:
J Thromb Haemost
Background Trauma-associated hemorrhage and coagulopathy remain leading causes of mortality. Such coagulopathy often leads to a hyperfibrinolytic phenotype where hemostatic clots become unstable because of upregulated tissue plasminogen activator (tP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39da5b748386156595a17da1c558fae
https://doi.org/10.1111/jth.14552
https://doi.org/10.1111/jth.14552
Autor:
Erin B. Lavik, Jeffrey S. Ustin, Mark Holland, DaShawn A. Hickman, Rebecca Groynom, Matt Varley, Nuzhat Maisha, Andrew J. Shoffstall, Chimdiya Onwukwe, Nishant Uppal
Publikováno v:
Bioconjugate Chemistry. 29:2436-2447
Bleeding from traumatic injury is the leading cause of death for young people across the world, but interventions are lacking. While many agents have shown promise in small animal models, translating the work to large animal models has been exception
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa316a17d3d962b43b4a16727396787
https://doi.org/10.1021/acs.bioconjchem.8b00335
https://doi.org/10.1021/acs.bioconjchem.8b00335
Autor:
DaShawn A. Hickman, Norman F. Luc, Matthew D. Neal, Mitchell Dyer, Christa L. Pawlowski, Shannon Haldeman, Anirban Sen Gupta, Patricia Loughran
Publikováno v:
Journal of Trauma and Acute Care Surgery. 84:917-923
BACKGROUND: Clinical resuscitative treatment of traumatic hemorrhage involves transfusion of RBC, platelets and plasma in controlled ratios. However, use of such blood components, especially platelets, present many challenges including availability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d846af223e403e56b8e73cd1603987d6
https://doi.org/10.1097/ta.0000000000001893
https://doi.org/10.1097/ta.0000000000001893
Autor:
Clarissa Kos, Gurbani Kaur, Christa L. Pawlowski, DaShawn A. Hickman, Kavya Ravichandran, Anirban Sen Gupta, Wei Li, Michael Sun
Publikováno v:
Biomaterials. 128:94-108
Intravascular administration of plasminogen activators is a clinically important thrombolytic strategy to treat occlusive vascular conditions. A major issue with this strategy is the systemic off-target drug action, which affects hemostatic capabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b113c2b32201d07488dbcff42905a7
https://doi.org/10.1016/j.biomaterials.2017.03.012
https://doi.org/10.1016/j.biomaterials.2017.03.012
Autor:
Ann H. Kim, Aditya Girish, Andrew Shevitz, Mitchell Dyer, Norman F. Luc, DaShawn A. Hickman, Vikram S. Kashyap, Christa L. Pawlowski, Anirban Sen Gupta, Stephanie Huang, Michael Sun, Ujjal D. S. Sekhon, Edward F. Niedoba, Matthew D. Neal, Joyann Marks, Simi Ganjoo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Traumatic non-compressible hemorrhage is a leading cause of civilian and military mortality and its treatment requires massive transfusion of blood components, especially platelets. However, in austere civilian and battlefield locations, access to pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fe88cc6fd03976fac9b8d95aa5fc13
https://pubmed.ncbi.nlm.nih.gov/29449604
https://pubmed.ncbi.nlm.nih.gov/29449604
Autor:
Ahmed El-Shamy, Jonathan A. Dranoff, Yedidya Saiman, DaShawn A. Hickman, Ritu Agarwal, Meena B. Bansal, Scott L. Friedman, Michel Fausther
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G375-G382
Liver fibrosis, with subsequent development of cirrhosis and ultimately portal hypertension, results in the death of patients with end-stage liver disease if liver transplantation is not performed. Hepatic stellate cells (HSCs), central mediators of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e529c947cbc70b6b3ad7a5edd36546a
https://doi.org/10.1152/ajpgi.00185.2012
https://doi.org/10.1152/ajpgi.00185.2012
Autor:
Christa L. Pawlowski, DaShawn A. Hickman, Ujjal D. S. Sekhon, Anirban Sen Gupta, Joyann Marks
Publikováno v:
Advanced Materials. 30:1804635
Bleeding complications arising from trauma, surgery, and as congenital, disease-associated, or drug-induced blood disorders can cause significant morbidities and mortalities in civilian and military populations. Therefore, stoppage of bleeding (hemos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637d41342c0d53124f335c6672aa3f25
https://doi.org/10.1002/adma.201804635
https://doi.org/10.1002/adma.201804635
Autor:
Giulia Baldini, Nina Sheung, Neal K. Bhatia, DaShawn A. Hickman, Jonathan A. Dranoff, Susana Granell, Michel Fausther, Elise G. Lavoie
Publikováno v:
Physiological Reports
Liver myofibroblasts derived from hepatic stellate cells (HSC) are critical mediators of liver fibrosis. Release of tissue inhibitor of metalloproteinase-1 (TIMP-1) advances liver fibrosis by blocking fibrinolysis. The mechanisms responsible for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10209cba8ec1d57176571f6318a12452
https://doi.org/10.1002/phy2.125
https://doi.org/10.1002/phy2.125
Autor:
Maria A. Townes, Marina Santiago, Farrah M. Kimovec, Neely E. Williams, Jeffrey Huang, DaShawn A. Hickman, Jonathan R. Russell, Paul A. Mittermiller, David Koppstein, Daniel H. Marks, Michael Vishnevetsky, Carol A. Bascom-Slack, Lori-Ann Boulanger, Kathleen W. Dantzler, Justin Jee, Pria Anand, Amanda Sandoval, Mario Percy Núñez Vargas, Scott A. Strobel, Salvador Joel Núñez, Kaury Kucera
Publikováno v:
Applied and environmental microbiology. 77(17)
Bioremediation is an important approach to waste reduction that relies on biological processes to break down a variety of pollutants. This is made possible by the vast metabolic diversity of the microbial world. To explore this diversity for the brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9e7b11b17163cca06ac17dbcefbb9d
https://pubmed.ncbi.nlm.nih.gov/21764951
https://pubmed.ncbi.nlm.nih.gov/21764951
Publikováno v:
Gastroenterology. 140:S-981
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4567bf3268229ecf5dfb60fc46c371d3
https://doi.org/10.1016/s0016-5085(11)64067-5
https://doi.org/10.1016/s0016-5085(11)64067-5